Published four times a year, the "British Medical Bulletin" provides up-to-date reviews on areas of current development and research. This volume focuses on spongiform encephalopathy, and should interest neurologists, psychiatrists, pathologists and researchers in veterinary medicine and biology.
Reihe
Sprache
Verlagsort
Verlagsgruppe
Zielgruppe
Für höhere Schule und Studium
Für Beruf und Forschung
Illustrationen
line drawings, half-tones, index
Maße
Höhe: 216 mm
Breite: 140 mm
Gewicht
ISBN-13
978-0-443-04928-6 (9780443049286)
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Schweitzer Klassifikation
Overview of the transmissible spongiform encephalopathies - prion protein disorders; neuropathology of spongiform encephalopathies in humans; scrapie pathogenesis; the diversity in the neuropathology of scrapie-like diseases in animals; inactivation of spongiform encephalopathy agents; scrapie strain variation and mutation; the PrP gene and its association with spongiform encephalopathies; scrapie associated PrP accumulation and its prevention - insights from cell culture; transgenics and cell biology of prion diseases - investigations of PrPSc synthesis and diversity; genetic control of nucleation and polymerization of host precursors to infectious amyloids in the transmissible amyloids of brain; molecular genetics of Gerstmann-Straussler-Scheinker syndrome; BSE epidemiology and control; epidemiology of Creutzfeldt-Jakob disease; developments in diagnosis; fatal familial insomnia and the widening spectrum of prion diseases; replication models (mice) and the future.
