Immunointervention in Autoimmunity by Th1/Th2 Regulation

Growing evidence indicates that T helper 1 (Th1) cells are involved in the pathogenesis of at least some autoimmune diseases whereas Th2 may act as regulatory cells to inhibit them. This book outlines therapeutic approaches based on the regulation of the Th1/Th2 cell balance. Basic clinical aspects of this attractive mode of immunointervention are reviewed by leading experts. The book focuses on immunointervention by Th1/Th2 regulation in autoimmunity, but similar approaches are applicable to immunointervention in infectious diseases, allergy, transplantation and cancer.