This special issue of Acta Haematologica contains selected papers presented at the 11th International Symposium on Molecular Biology of Hematopoiesis, held in Bormio, Italy in June 1998. The following topics are considered: - the use of BMT for organ transplantation and autoimmune disease - new methods for stable gene transfer with increased transduction rate into pluripotent human stem cells - the state of the art in retrovirus gene transfer - the use of adenoviral- and retroviral-mediated interferon gene transfer for a possible treatment of patients with chronic myelogenous leukemia and colon cancer Bringing together the experience of leading specialists, this publication will be appreciated by hematologists, oncologists, and scientists working on gene therapy.
Sprache
Verlagsort
Zielgruppe
Illustrationen
Maße
Gewicht
ISBN-13
978-3-8055-6823-4 (9783805568234)
Schweitzer Klassifikation
New strategies for allogeneic bone marrow transplantation and organ allografts; mixed allogeneic chimerism to induce tolerance to solid organ and cellular grafts; synergetic effects of retrovirus IFN-a gene transfer and 5-FU on apoptosis of colon cancer cells; gene therapy for severe combined immunodeficiency caused by adenosine deaminase deficiency - improved retroviral vectors for clinical trials; adenovirus p53 purging for human breast cancer stem cell products; retroviral-mediated transfer and expression of the common gamma chain into human haematopoietic progenitors.
