Refractory Chronic Rhinosinusitis, An Issue of Otolaryngologic Clinics of North America
1. Auflage
Erschienen am 29. November 2016
100 Seiten
978-0-323-49670-4 (ISBN)
Beschreibung
This issue of Otolaryngologic Clinics, guest edited by Drs. Abtin Tabaee and Edward D. McCoul, is devoted to Refractory Chronic Rhinosinusitis. Articles in this issue include: Classification of Chronic Rhinosinusitis: Working Towards Personalized Diagnosis; Bacterial Pathogens and the Microbiome; Biofilm and Osteitis; Refractory Chronic Sinusitis with Polyposis; Aspirin-Exacerbated Respiratory Disease; Systemic and Odontogenic Etiologies in Chronic Rhinosinusitis; Genetic and Immune Dysregulation in Chronic Rhinosinusitis; Office Procedures in Refractory Chronic Rhinosinusitis; Topical Therapies and Stents; Revision Functional Endoscopic Sinus Surgery; Extended Endoscopic and Open Sinus Surgery for Refractory Chronic Rhinosinusitis; and An Algorithm for Comprehensive Evaluation and Management of Refractory Chronic Rhinosinusitis.
Weitere Details
Weitere Ausgaben
Andere Ausgaben
Abtin Tabaee | Edward D. McCoul
Refractory Chronic Rhinosinusitis, An Issue of Otolaryngologic Clinics of North America: Volume 50-1
Buch
04/2017
Elsevier
101,22 €
Versand in 15-20 Tagen
Inhalt
- Front Cover
- Refractory Chronic Rhinosinusitis
- Copyright
- CME Accreditation Page
- PROGRAM OBJECTIVE
- LEARNING OBJECTIVES
- ACCREDITATION
- DISCLOSURE OF CONFLICTS OF INTEREST
- UNAPPROVED/OFF-LABEL USE DISCLOSURE
- TO ENROLL
- METHOD OF PARTICIPATION
- CME INQUIRIES/SPECIAL NEEDS
- Contributors
- CONSULTING EDITOR
- EDITORS
- AUTHORS
- Contents
- Foreword: Chronic Rhinosinusitis: A "Simple" Complex Condition
- Preface: Refractory Chronic Rhinosinusitis
- Classification of Chronic Rhinosinusitis-Working Toward Personalized Diagnosis
- Genetic and Immune Dysregulation in Chronic Rhinosinusitis
- Bacterial Pathogens and the Microbiome
- Biofilm and Osteitis in Refractory Chronic Rhinosinusitis
- Refractory Chronic Rhinosinusitis with Nasal Polyposis
- Aspirin-Exacerbated Respiratory Disease
- Systemic and Odontogenic Etiologies in Chronic Rhinosinusitis
- Office Procedures in Refractory Chronic Rhinosinusitis
- Topical Therapies for Refractory Chronic Rhinosinusitis
- Revision Functional Endoscopic Sinus Surgery
- Extended Endoscopic and Open Sinus Surgery for Refractory Chronic Rhinosinusitis
- A Practical Approach to Refractory Chronic Rhinosinusitis
- OTOLARYNGOLOGIC CLINICS OF NORTH AMERICA
- FORTHCOMING ISSUES
- April 2017
- June 2017
- August 2017
- RECENT ISSUES
- December 2016
- October 2016
- August 2016
- Foreword: Chronic Rhinosinusitis: A "Simple" Complex Condition
- Preface: Refractory Chronic Rhinosinusitis
- Classification of Chronic Rhinosinusitis-Working Toward Personalized Diagnosis
- Key points
- INTRODUCTION
- Epidemiology
- Questionnaire-Based Evaluations
- Clinical Evaluations
- SOCIETAL BURDEN OF CHRONIC RHINOSINUSITIS
- Burden to the Individual
- Burden to Society
- PRECISION MEDICINE
- CLASSIFICATION OF CHRONIC RHINOSINUSITIS
- Phenotypic Classification of chronic rhinosinusitis
- Endotyping chronic rhinosinusitis
- Microbiomic classification of chronic rhinosinusitis
- Genomic classification of chronic rhinosinusitis
- SUMMARY
- REFERENCES
- Genetic and Immune Dysregulation in Chronic Rhinosinusitis
- Key points
- INTRODUCTION
- Innate Immunity and Epithelial Barrier Dysfunction in Chronic Rhinosinusitis
- Genetics of Innate Immunity in Chronic Rhinosinusitis
- Acyloxyacyl hydroxylase
- Bitter taste receptors
- Cystic Fibrosis Transmembrane Regulator Locus
- Adaptive Immunity in Chronic Rhinosinusitis
- Genetics of Adaptive Immune Dysfunction in Chronic Rhinosinusitis
- IL1A
- Tumor necrosis factor-a
- Immunodeficiency in Chronic Rhinosinusitis
- SUMMARY
- REFERENCES
- Bacterial Pathogens and the Microbiome
- Key points
- INTRODUCTION
- Chronic Rhinosinusitis Pathophysiology and Immune Homeostasis
- Innate versus adaptive immunity
- Surface mucosal niche
- Role of Bacteria in Initiation and Sustenance of Inflammation
- THE PARANASAL SINUS BIOME IN HEALTH AND DISEASE
- The Microbiome
- Bacteria in Health
- Microbiome Changes in Disease
- Are Microbiome Alterations a Cause or By-product of Disease?
- CLINICAL IMPLICATIONS AND TREATMENT CONSIDERATIONS OF BACTERIAL PATHOGENS
- Pathogens Often Implicated in Chronic Rhinosinusitis
- Traditional culture-based study versus molecular techniques
- Staphylococcus aureus and Superantigens
- Pseudomonas aeruginosa
- Anaerobes
- Antibiotic Resistance Associated with Pathogens in Chronic Rhinosinusitis Study
- EMERGING RESEARCH CONCEPTS IN THE MICROBIOME
- Role in Mucosal Immune Function
- Dysbiosis and Community Dynamics
- Determinants of the Human Microbiome
- Restoring a Healthy Microbiome: Prebiotics and Probiotics
- A GENERAL APPROACH TO ANTIBIOTIC THERAPY FOR REFRACTORY CHRONIC RHINOSINUSITIS
- Current Guidelines for Antibiotics in Chronic Rhinosinusitis
- Bacteria: Good, Bad, or Just There?
- REFERENCES
- Biofilm and Osteitis in Refractory Chronic Rhinosinusitis
- Key points
- BIOFILM IN REFRACTORY CHRONIC RHINOSINUSITIS
- Definition of Biofilm
- Detection of Biofilm
- Characterization of biofilm
- Limitation of current techniques
- Pathophysiology of Biofilm and Its Role in Refractory Chronic Rhinosinusitis
- Does biofilm equal disease?
- How does biofilm contribute to refractory chronic rhinosinusitis?
- Treatment of Biofilm
- Surgery
- Topical steroids
- Topical antibiotics
- Surfactants
- Other experimental treatments
- OSTEITIS IN REFRACTORY CHRONIC RHINOSINUSITIS
- Definitions of Osteitis
- Prevalence of Osteitis
- Pathophysiology of Osteitis
- Biofilm association
- Disease Severity and Osteitis
- Diagnosis of Osteitis
- Computed tomography scan
- Scoring system
- Single-photon emission computed tomography
- Histology
- Implication for Treatment of Osteitis
- Surgery
- Antibiotics
- SUMMARY
- REFERENCES
- Refractory Chronic Rhinosinusitis with Nasal Polyposis
- Key points
- CHRONIC RHINOSINUSITIS WITH NASAL POLYPOSIS
- ASTHMA, ALLERGY, AND EOSINOPHILIA
- ALLERGIC FUNGAL SINUSITIS
- CYSTIC FIBROSIS
- INNATE IMMUNITY AND CYTOKINES
- STAPHYLOCOCCAL SUPERANTIGENS
- TREATMENT
- SUMMARY
- REFERENCES
- Aspirin-Exacerbated Respiratory Disease
- Key points
- INTRODUCTION
- CLINICAL PRESENTATION
- PATHOPHYSIOLOGY
- ASTHMA IN ASPIRIN-EXACERBATED RESPIRATORY DISEASE
- CHRONIC RHINOSINUSITIS IN ASPIRIN-EXACERBATED RESPIRATORY DISEASE
- TREATMENT OPTIONS FOR ASPIRIN-EXACERBATED RESPIRATORY DISEASE-RELATED CHRONIC RHINOSINUSITIS
- Antileukotriene Therapy
- Antibiotic Therapy
- Omalizumab
- Oral Corticosteroids
- Surgical Management
- ASPIRIN CHALLENGE AND DESENSITIZATION
- OUTCOMES OF ASPIRIN DESENSITIZATION
- SUMMARY
- REFERENCES
- Systemic and Odontogenic Etiologies in Chronic Rhinosinusitis
- Key points
- INTRODUCTION
- SYSTEMIC ETIOLOGIES OF CHRONIC RHINOSINUSITIS
- Cystic Fibrosis
- Sarcoidosis
- Eosinophilic Granulomatosis with Polyangiitis (Churg-Strauss Syndrome)
- Granulomatosis with Polyangiitis (Wegener's Granulomatosis)
- Primary Ciliary Dyskinesia
- ODONTOGENIC SINUSITIS
- SUMMARY
- REFERENCES
- Office Procedures in Refractory Chronic Rhinosinusitis
- Key points
- INTRODUCTION
- PROCEDURE ROOM SETUP
- PATIENT SELECTION
- INTRANASAL PREPARATION
- OFFICE-BASED POLYPECTOMY
- Indication
- Patient Selection
- Procedure
- Possible Complications
- Postprocedure Considerations
- IN-OFFICE TREATMENT OF MUCOCELES
- Indication
- Procedure
- Possible Complications
- IN-OFFICE SEPTOPLASTY
- Indication
- Procedure
- Possible Complications
- IN-OFFICE MANAGEMENT OF STENOSIS AND SYNECHIAE
- Indication
- Procedures
- Possible Complications
- BALLOON DILATION
- Indications
- Procedure
- Possible Complications
- Postprocedure Considerations
- STEROID-ELUTING STENTS
- Patient Selection
- Procedure
- Possible Complications
- Postprocedure Considerations
- TOPICAL THERAPY APPLIED IN OFFICE
- Topical Antibiotic Irrigation
- Topical Chemical Surfactant
- Impregnated Topical Gel Therapy
- Photodynamic Therapy
- SUMMARY
- REFERENCES
- Topical Therapies for Refractory Chronic Rhinosinusitis
- Key points
- OVERVIEW
- METHODS OF DELIVERY
- TOPICAL SINONASAL SALINE
- TOPICAL SINONASAL STEROIDS
- TOPICAL SINONASAL ANTIBIOTICS
- TOPICAL SINONASAL ANTIFUNGALS
- TOPICAL SINONASAL STENTS
- OTHER TOPICAL SINONASAL THERAPIES
- SUMMARY
- REFERENCES
- Revision Functional Endoscopic Sinus Surgery
- Key points
- INTRODUCTION
- REASONS FOR FAILURE OF PRIMARY FUNCTIONAL ENDOSCOPIC SINUS SURGERY
- Anatomic, Mucosal, and Bony Factors
- Incomplete surgery
- Ostium stenosis, scaring, and synechiae
- Recirculation
- Neo-osteogenesis
- Recurrent mucosal disease
- Patient Disease
- Allergic fungal sinusitis
- Impaired secretion clearance
- Biofilms
- Immune deficiencies
- Aspirin-exacerbated respiratory disease
- Postoperative Care
- Medical treatment
- Endoscopic debridements
- Allergy assessment and treatment
- TREATMENT OF RECALCITRANT SINUSITIS
- Maximize Medical and Nonsurgical Treatments
- Principles of Revision Surgery
- Landmarks and Surgical Approach
- Nasal landmarks
- Maxillary antrostomy
- Ethmoidectomy
- Sphenoidotomy
- Frontal sinusotomy
- Advanced Procedures to Address Specific Issues in Severe Recurrent Disease
- Maxillary disease inaccessible with a wide middle meatal antrostomy
- Insufficient frontal sinus opening achieved by Draf I frontal sinusotomy
- Neo-osteogenesis of the frontal prevents location of the infundibulum
- REVISION SINUS SURGERY OUTCOMES
- REFERENCES
- Extended Endoscopic and Open Sinus Surgery for Refractory Chronic Rhinosinusitis
- Key points
- INTRODUCTION
- EXTENDED MAXILLARY SINUS PROCEDURES
- Endoscopic Maxillary Mega-Antrostomy
- Endoscopic Modified Medial Maxillectomy
- Endoscopic-Assisted Sublabial Anterior Maxillotomy
- Inferior Meatal Antrostomy
- EXTENDED ETHMOID SINUS PROCEDURES
- Complete Total Ethmoidectomy with Mucosal Stripping
- External Frontoethmoidectomy
- EXTENDED SPHENOID SINUS PROCEDURES
- EXTENDED FRONTAL SINUS PROCEDURES
- EXTENDED ENDOSCOPIC FRONTAL SINUS APPROACHES
- Draf IIB
- Modified Lothrop Procedure
- Modified Lothrop Procedure Modifications
- Modified hemi-Lothrop procedure
- Modified mini-Lothrop procedure
- Modified subtotal-Lothrop procedure
- Modified central-Lothrop procedure
- EXTERNAL FRONTAL SINUS APPROACHES
- Frontal Sinus Trephine
- External Frontoethmoidectomy
- Frontal Sinus Osteoplastic Flap with or Without Obliteration
- Frontal Sinus Cranialization
- SUMMARY
- SUPPLEMENTARY DATA
- REFERENCES
- A Practical Approach to Refractory Chronic Rhinosinusitis
- Key points
- INTRODUCTION
- DIAGNOSTIC EVALUATION OF REFRACTORY CHRONIC RHINOSINUSITIS
- General Principles
- Patient History
- Clinical Examination
- Imaging
- Microbiology
- Pathology
- Host, Environmental, and Disease Cofactors
- Chronic Rhinosinusitis Phenotypes
- Future Considerations in Diagnosis
- PRINCIPLES OF TREATMENT OF REFRACTORY CHRONIC RHINOSINUSITIS
- Assumptions of Treatment
- Treatment of Chronic Rhinosinusitis with Polyposis
- Nonsurgical treatment
- Surgical treatment
- Treatment of Nonpolypoid Chronic Rhinosinusitis
- Nonsurgical treatment
- Surgical treatment
- Treatment of Chronic Rhinosinusitis in Cystic Fibrosis
- Nonsurgical treatment
- Surgical treatment
- Treatment of Aspirin-Exacerbated Respiratory Disease
- Nonsurgical treatment
- Surgical treatment
- Treatment of Other Special Cases
- SUMMARY
- REFERENCES
- Index
