
Biomarkers in Cancer Screening and Early Detection
Sudhir Srivastava(Herausgeber*in)
Wiley-Blackwell (Verlag)
Erschienen am 7. Juni 2017
320 Seiten
978-1-118-46882-1 (ISBN)
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Beschreibung
Prepared by world leaders on this topic, Biomarkers in Cancer Screening and Early Detection offers a comprehensive, state-of-the-art perspective on the various research and clinical aspects of cancer biomarkers, from their discovery and development to their validation, clinical utility, and use in developing personalized cancer treatment.
* Offers a comprehensive, state-of-the-art perspective on the various research and clinical aspects of cancer biomarkers
* Provides immediately actionable information and hopefully also inspiration to move discovery and clinical application forward
* Offers vital knowledge to help develop personalized cancer treatment for individual patients with specific cancers
Weitere Details
Reihe
Auflage
1. Auflage
Sprache
Englisch
Verlagsgruppe
John Wiley & Sons
Dateigröße
2,59 MB
ISBN-13
978-1-118-46882-1 (9781118468821)
Schweitzer Klassifikation
Weitere Ausgaben
Person
Edited by
Sudhir Srivastava, Ph.D., MPH Senior Scientific Officer, Chief, Cancer Biomarkers Research Group, Divisionof Cancer Prevention, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
Translational Oncology Series
Series Editors
ROBERT C. BAST, MD, Vice President for Translational Research, The University of Texas MD Anderson CancerCenter, Houston, TX, USA
MAURIE MARKMAN, MD, Senior Vice President for Clinical Affairs, Cancer Treatment Centers of America,Clinical Professor of Medicine, Drexel University College of Medicine, Philadelphia, PA, USA
ERNEST HAWK, MD, MPH, Vice President, Division of OVP, Cancer Prevention and Population Sciences,The University of Texas MD Anderson Cancer Center, Houston, TX, USA
Herausgeber*in
Division of Cancer Prevention, National Cancer Institute, Bethesda, MD, USA
Inhalt
List of Contributors, ix
Preface, xiii
Part I Foundations of Biomarker Research
1 Nuts and Bolts of Biomarker Research, 3
Sharmistha Ghosh and Sudhir Srivastava
2 Cancer Genome Methylation: Biology, Biomarker and Therapeutic Opportunities, 16
Shashwat Sharad, Taduru Sreenath, Shiv Srivastava, and Albert Dobi
3 MicroRNA Biomarkers for Early Detection of Cancer, 27
WendyWang, Matthew R Young, and Sudhir Srivastava
4 Inflammation and Cancer, 37
Pamela L Beatty, Sandra Cascio, and Olivera J Finn
5 Exosomes: A Valuable Biomedical Tool in Biomarker Discovery and Development, 50
Jocelyn Lee, Sharmistha Ghosh, and Sudhir Srivastava
6 Epithelial-to-Mesenchymal Transition (EMT): Clinical Implications, 64
Elisa CWoodhouse and Suresh Mohla
Part II State-of-the-Science in Organ-Specific Biomarker Research
7 Breast Cancer, 77
Benjamin A Katchman, Christos Patriotis, and Karen S Anderson
8 Ovarian Cancer, 93
Christos Patriotis, Archana Simmons, Karen H Lu, Robert C Bast, Jr, and Steven J Skates
9 Esophageal Cancer Biomarkers, 104
Yanxin Luo, Kishore Guda, SanfordD Markowitz, Amitabh Chak, Andrew M Kaz, andWilliam M Grady
10 Predictive Biomarkers for Therapy in Adenocarcinoma of the Upper Digestive Tract, 118
Heath D Skinner, Qiongrong Chen, Elena Elimova, RoopmaWadhwa, Shumei Song, and Jaffer A Ajani
11 Pancreatic Cancer, 130
Sam CWang and Peter J Allen
12 Colon Cancer, 141
Paul DWagner
13 Prognostic and Predictive Biomarkers for Colorectal Cancer, 151
Upender Manne, Balananda-Dhurjati Kumar Putcha, Temesgen Samuel, and Sudhir Srivastava
14 Early Detection of Lung Cancer, 163
Mohamed Hassanein, Melinda C Aldrich, Stephen A Deppen, Karl E Krueger, Eric L Grogan, and Pierre P Massion
15 Commonalities in Lung Cancer and COPD, 185
MalgorzataWojtowicz and Eva Szabo
16 Prostate Cancer, 197
Jacob Kagan, Ian M Thompson, and DanielWChan
Part III Biomarkers, Screening and Precision Health: Implications for Public Health
17 Improving the Clinical Validity of Biomarker Research in Cancer Detection, 209
David F Ransohoff
18 Cancer Overdiagnosis, Ramifications and Research Strategies, 220
Barbara K Dunn and Barnett S Kramer
19 Predictive Markers and Driver Genes From Treatment Trials: Potential Utility For Early Diagnosis, 231
Brian S Sorg, Sarfraz Memon, Kelly Y Kim, Aniruddha Ganguly, Tracy Lively, James Tricoli, Magdalena Thurin, Lokesh Agrawal, Tawnya C McKee, Barbara A Conley, and J Milburn Jessup
20 Statistical Consideration in Predictive and Prognostic Markers, 245
Fei Ye and Yu Shyr
21 Clinical Validation of Molecular Biomarkers in Translational Medicine, 256
Harry B Burke and William E Grizzle
22 Cancer Biomarker Assays: Performance Standards, 267
Anna K Fuzery and Daniel W Chan
23 Bioethics and Cancer Biomarker Research, 277
Nathan Nobis, William Grizzle, and Stephen Sodeke
24 Colon Cancer Screening, 283
Molly Perencevich, Jennifer Inra, and Sapna Syngal
List of Contributors
- Lokesh Agrawal
- Cancer Diagnosis Program, Division of Cancer Treatment and Diagnosis, Bethesda, MD, USA
- Jaffer A Ajani
- Professor, Department of GI Medical Oncology, The University of Texas MD Anderson Cancer Centre, Houston, TX, USA
- Melinda C Aldrich
- Department of Thoracic Surgery and Division of Epidemiology, Vanderbilt University Medical Centre, Nashville, TN, USA
- Peter J Allen
- Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, NY, USA
- Karen S Anderson
- Center for Personalized Diagnostics, Biodesign Institute, Arizona State University, Tempe, AZ, USA
- Robert C Bast, Jr.
- Department of Experimental Therapeutics, University of Texas MD Anderson Cancer Center, Houston, TX, USA
- Pamela L Beatty
- Department of Immunology, University of Pittsburgh School of Medicine, PA, USA
- Harry B Burke
- Biomedical Informatics and Medicine Departments, F. Edward Herbert School of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD, USA
- Sandra Cascio
- Department of Immunology, University of Pittsburgh School of Medicine, PA, USA
- Fondazione RiMED, Palermo, Italy
- Amitabh Chak
- Gastroenterology Division, Case Western Reserve University, University Hospitals of Cleveland, Cleveland, OH, USA
- Daniel W Chan
- Department of Pathology, John Hopkins University School of Medicine, Baltimore, MD, USA
- Center for Biomarker Discovery and Translation, John Hopkins Medical Institutions, Baltimore, MD, USA
- Qiongrong Chen
- Postdoctoral fellow, Department of GI Medical Oncology, The University of Texas MD Anderson Cancer Centre, Houston, TX, USA
- Barbara A Conley
- Cancer Diagnosis Program, Division of Cancer Treatment and Diagnosis, Bethesda, MD, USA
- Stephen A Deppen
- Department of Thoracic Surgery, Vanderbilt University Medical Centre, Nashville, TN, USA
- Albert Dobi
- Center for Prostate Disease Research, Department of Surgery, Uniformed Services University of the Health Sciences, Rockville, MD, USA
- Barbara K Dunn
- National Cancer Institute, Division of Cancer Prevention, Chemoprevention Agent Development Research Group, Bethesda, MD, USA
- Elena Elimova
- Postdoctoral fellow, Department of GI Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
- Olivera J Finn
- Department of Immunology, University of Pittsburgh School of Medicine, PA, USA
- Anna K Füzéry
- Department of Laboratory Medicine and Pathology, University of Albert, Edmonton, AB, Canada
- Alberta Health Services, Edmonton, AB, Canada
- Aniruddha Ganguly
- Cancer Diagnosis Program, Division of Cancer Treatment and Diagnosis, Bethesda, MD, USA
- Sharmistha Ghosh
- Cancer Biomarkers Research Group, Division of Cancer Prevention, National Cancer Institute, Rockville, MD, USA
- William M Grady
- Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA
- Department of Medicine, University of Washington School of Medicine, Seattle, WA, USA
- William E Grizzle
- Department of Pathology, University of Alabama at Birmingham, Birmingham, AL, USA
- Eric L Grogan
- Veterans Affairs, Tennessee Valley Healthcare System, Nashville Campus, Department of Thoracic Surgery Medical Centre, Nashville, TN, USA
- Kishore Guda
- General Medical Sciences-Oncology, Case Western Reserve University, University Hospitals of Cleveland, Cleveland, OH, USA
- Mohamed Hassanein
- Division of Allergy, Pulmonary and Critical Care Medicine, Vanderbilt-Ingram Cancer Centre, TN, USA
- Jennifer Inra
- Division of Population Sciences, Dana-Farber Cancer Institute, Boston, MA, USA
- Division of Gastroenterology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA
- J Milburn Jessup
- Cancer Diagnosis Program, Division of Cancer Treatment and Diagnosis, Bethesda, MD, USA
- Jacob Kagan
- Division of Cancer Prevention, National Cancer Institute, Bethesda, MD, USA
- Benjamin A Katchman
- Center for Personalized Diagnostics, Biodesign Institute, Arizona State University, Tempe, AZ, USA
- Andrew M Kaz
- Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA
- Research and Development Service, VA Puget Sound Health Care System, Seattle, WA, USA
- Department of Medicine, University of Washington School of Medicine, Seattle, WA, USA
- Kelly Y Kim
- Cancer Diagnosis Program, Division of Cancer Treatment and Diagnosis, Bethesda, MD, USA
- Barnett S Kramer
- National Cancer Institute, Division of Cancer Prevention, Bethesda, MD, USA
- Karl E Krueger
- Division of Cancer Prevention, National Cancer Institute, National Institutes of Health, Rockville, MD, USA
- Jocelyn Lee
- Cancer Biomarkers Research Group, Division of Cancer Prevention, National Cancer Institute, Rockville, MD, USA
- Tracy Lively
- Cancer Diagnosis Program, Division of Cancer Treatment and Diagnosis, Bethesda, MD, USA
- Karen H Lu
- Department of Gynecologic Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA
- Yanxin Luo
- Department of Colorectal Surgery, The Sixth Affiliated Hospital, Sun Yat-Sen University, Guangzhou, P.R. China
- Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA
- Upender Manne
- Department of Pathology and Comprehensive Cancer Center, University of Alabama Birmingham, AL, USA
- Sanford D Markowitz
- Oncology Division, Case Western Reserve University, University Hospitals of Cleveland, Cleveland, OH, USA
- Pierre P Massion
- Division of Allergy, Pulmonary and Critical Care Medicine, Vanderbilt-Ingram Cancer Centre, Veterans Affairs, Tennessee Valley Healthcare System, Nashville Campus, TN, USA
- Tawnya C McKee
- Cancer Diagnosis Program, Division of Cancer Treatment and Diagnosis, Bethesda, MD, USA
- Sarfraz Memon
- Cancer Diagnosis Program, Division of Cancer Treatment and Diagnosis, Bethesda, MD, USA
- Suresh Mohla
- Tumour Biology and Metastasis Branch, Division of Cancer Biology, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
- Nathan Nobis
- Morehouse School of Medicine and Morehouse College, Atlanta, GA, USA
- Christos Patriotis
- Cancer Biomarkers Research Group, Division of Cancer Prevention, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
- Molly Perencevich
- Division of Population Sciences, Dana-Farber Cancer Institute, Boston, MA, USA
- Division of Gastroenterology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA
- Balananda-Dhurjati Kumar Putcha
- Department of Pathology, University of Alabama, Birmingham, AL, USA
- David F Ransohoff
- Department of Medicine, Lineberger Comprehensive Cancer Centre, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA
- Temesgen Samuel
- Centre for Cancer Research and Department of Pathobiology, Tuskegee University, Tuskegee, AL, USA
- Shashwat Sharad
- Center for Prostate Disease Research, Department of Surgery, Uniformed Services University of the Health Sciences, Rockville, MD, USA
- Yu Shyr
- Professor, Department of Biostatistics, Vanderbilt University School of Medicine, Nashville, TN, USA
- Archana Simmons
- Department of Experimental Therapeutics, University of Texas MD Anderson Cancer Center, Houston, TX, USA
- Steven J Skates
- Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA
- Heath D Skinner
- Assistant Professor, Department of Radiation Oncology, The University of Texas MD Anderson Cancer Centre, Houston, TX, USA
- Stephen Sodeke
- Tuskegee University National Centre for Bioethics in Research and Health Care, Tuskegee, AL, USA
- Shumei Song
- Assistant Professor, Department of GI Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
- Brian S Sorg
- Cancer Diagnosis Program, Division of Cancer Treatment and Diagnosis, Bethesda, MD, USA
- Taduru Sreenath
- Centre for Prostate Disease Research, Department of Surgery, Uniformed Services University of the Health Sciences, Rockville, MD, USA
- Sudhir Srivastava
- Cancer Biomarkers Research Group, Division of Cancer Prevention, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
- Shiv Srivastava
- Centre for Prostate Disease Research, Department of Surgery, Uniformed Services University of the Health Sciences, Rockville, MD, USA
- Sapna Syngal
- Division of Population Sciences, Dana-Farber Cancer Institute, Boston, MA, USA
- Division of Gastroenterology, Brigham and...
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