Stem Cell Engineering
Principles and Practices
1. Auflage
Erschienen am 20. November 2012
230 Seiten
978-1-4398-7418-9 (ISBN)
Beschreibung
While the potential of stem cells is recognized, their proliferation and differentiation must be more precisely controlled to maximize the production of therapeutically relevant cells and for cell replacement therapies to minimize contamination with residual cells that can give rise to side effects. With contributions from pioneers and experts, this book provides a broad overview of the challenges of stem cell engineering. It discusses advances made during the last decade that have led to increasingly defined culture systems for growing human ES cells, starting from co-culture with feeder cells in the presence of serum to growth on synthetic substrates in defined medium. The book highlights recent advances in the understanding of the cellular and molecular composition of the hematopoietic stem cell niche, as well as approaches to build upon this basic information to direct stem cell differentiation into blood cell lineages.
Weitere Details
Auflage
1. Auflage
Sprache
Englisch
Verlagsort
Baton Rouge
USA
Verlagsgruppe
Taylor & Francis Inc
Zielgruppe
Für Beruf und Forschung
Illustrationen
10 s/w Tabellen, 26 s/w Abbildungen
26 b/w images, 10 tables and SEE
Dateigröße
12,40 MB
ISBN-13
978-1-4398-7418-9 (9781439874189)
Copyright in bibliographic data and cover images is held by Nielsen Book Services Limited or by the publishers or by their respective licensors: all rights reserved.
Schweitzer Klassifikation
Weitere Ausgaben
Personen
David Schaffer, Joseph D. Bronzino, Donald R. Peterson
Inhalt
Engineering the Pluripotent Stem Cell Niche for Directed Mesoderm Differentiation. Cell Mechanobiology in Regenerative Medicine: Lessons from Cancer. Systems-Engineering Principles in Signal Transduction and Cell-Fate Choice. Biomaterial Scaffolds for Human Embryonic Stem Cell Culture and Differentiation. Stem Cells and Regenerative Medicine in the Nervous System. Stem Cells and Regenerative Medicine for Treating Damaged Myocardium. Stem Cells and Hematopoiesis. Synthetic Biomaterials and Stem Cells for Connective Tissue Engineering. Derivation and Expansion of Human Pluripotent Stem Cells. Bioreactores for Stem Cell Explansion and Differentiation.
