Chromatographic Methods and Research

Name: Chromatographic Methods and Research
Brand: Nova Science Publishers Inc
Price: 241.99 EUR
Availability: OnlineOnly

W. Obrien Raven(Herausgeber*in)

Nova Science Publishers Inc

Erschienen am 18. Oktober 2023

195 Seiten

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979-8-89113-203-0 (ISBN)

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Inhalt

Intro
Contents
Preface
Chapter 1
Beta-Lactam Agents Serum Measurements by Liquid Chromatography to Evaluate Meropenem and Piperacillin Effectiveness in Septic Burn Adults with a Pharmacokinetic-Pharmacodynamic Approach
Abstract
Abbreviations
Introduction
Rational of Study
Bioanalytical Method for Beta-Lactam Serum Levels
Meropenem
Piperacillin
Clinical Trial: Patient Eligibility, Beta-Lactams Therapy, Blood Sampling, Pharmacokinetics, PK/PD Approach
Analytical Procedures for Drug Serum Measurements
Clinical Studies
Clinical Meropenem Study
Clinical Piperacillin Study
Conclusion
Disclaimer
References
Biographical Sketches
Chapter 2
Preconcentration Strategies Coupled with Chromatographic Methods for the Determination of Organic Compounds
Abstract
Introduction
Liquid-Liquid Extraction (LLE)
Solid-Phase Extraction (SPE)
Applications
Conclusion
References
Chapter 3
Bioanalytical Methods Based on Liquid Chromatography for the Therapeutic Drug Monitoring of Combined Therapies of Antibiotics in Pediatric Septic Major Burns
Abstract
Introduction
Rational of Study
Bioanalytical Method
Clinical Trial: Study Design and Patient Eligibility, Combined Therapy, Blood Sampling, PK/PD Approach
Analytical Procedures for Drug Serum Measurements
Clinical Study
Vancomycin Effectiveness Based on Serum Monitoring
Meropenem Effectiveness Based on Serum Monitoring
Conclusion
Disclaimer
References
Biographical Sketch
Chapter 4
Liquid Chromatography-Tandem Mass Spectrometry for Simultaneous Piperacillin-Meropenem Serum Measurements in Septic Burns for Effectiveness
Abstract
Abbreviations
Introduction
Rational of Study
Bioanalytical Method
Clinical Trial Study: Study Design, Patient Eligibility, Meropenem and Piperacillin Therapy
Analytical Procedures
Clinical Study Meropenem and Piperacillin
Conclusion
Disclaimer
References
Chapter 5
A Brief Review of Chromatographic Methods for the Quantification of Favipiravir
Abstract
Introduction
The Basic Principles of Chromatography Separation
Favipiravir
Mode of Action
Physiological Properties and Stability of FVPR
Pharmacology, Pharmacokinetics and Pharmacodynamics of FVPR
Analysis of FVPR by Various Chromatographic Techniques
Sample Treatment
Standard Stock Solution
Sample Solution- Pharmaceutical Formulation
Sample Solution-Blood Sample
High Performance Liquid Chromatography (HPLC)
High-Performance Liquid Chromatography and Tandem Mass Spectrometry (HPLC-MS/MS)
Gas Chromatography (GC)
High Performance Thin Layer Chromatography (HPTLC)
Conclusion
Disclaimer
References
Biographical Sketch
Chapter 6
Advances in Quantitative Liquid Chromatography-Mass Spectroscopy for Central Nervous System Melanocortin Hormone Quantification
Abstract
Introduction
Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS) Method to Measure a-MSH and Its Analogous Compounds in the Brain
Standard Internal (IS)
Sample Preparation
Sample Collection
Extraction Procedures
Mass Spectrum Ion Detection
Discussion
Conclusion
Disclaimer
References
Index
Blank Page

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