Allergic Skin Diseases, An Issue of Immunology and Allergy Clinics of North America
1. Auflage
Erschienen am 24. November 2016
100 Seiten
978-0-323-49661-2 (ISBN)
Beschreibung
This issue of Immunology and Allergy Clinics, guest edited by Drs. Peck Ong and Peter Schmid-Grendelmeier, is devoted to Allergic Skin Diseases. Articles in this issue include Wet-wrap Therapy in Atopic Dermatitis; Biologics in Chronic Urticaria; Clinical Measures of Chronic Urticaria; Cutaneous Manifestation of Drug Allergy; Itch in Atopic Dermatitis; Biomarkers in Atopic Dermatitis; Differential Diagnosis of Atopic Dermatitis; Differential Diagnosis of Chronic Urticaria; ACE-inhibitor-induced Angioedema; The Role of Fungi in Atopic Dermatitis; Cutaneous Manifestation of Food Allergy; Pediatric Mastocytosis; Allergic Contact Dermatitis; Hereditary Angioedema; Infectious Complications in Atopic Dermatitis; and Cutaneous Manifestations Primary Immunodeficiency/Autoimmunity.
Weitere Details
Weitere Ausgaben
Andere Ausgaben
Peck Ong | Peter Schmid-Grendelmeier
Allergic Skin Diseases, An Issue of Immunology and Allergy Clinics of North America: Volume 37-1
Buch
05/2017
Elsevier
91,35 €
Versand in 15-20 Tagen
Inhalt
- Front Cover
- Allergic Skin Diseases
- Copyright
- Contributors
- CONSULTING EDITOR
- EDITORS
- AUTHORS
- Contents
- Foreword: Allergic Skin Disease and the Practicing Allergist: Growing Unmet Need, New Science, and New Treatments
- Preface: Allergic Skin Diseases
- Atopic Dermatitis and Allergic Urticaria: Cutaneous Manifestations of Immunodeficiency
- Differential Diagnosis of Atopic Dermatitis
- Clinical Measures of Chronic Urticaria
- Current and Future Biomarkers in Atopic Dermatitis
- The Role of Fungi in Atopic Dermatitis
- Infectious Complications in Atopic Dermatitis
- Biologics in Chronic Urticaria
- Itch in Atopic Dermatitis
- Wet Wrap Therapy in Moderate to Severe Atopic Dermatitis
- Allergic Contact Dermatitis
- Mastocytosis and Anaphylaxis
- Cutaneous Manifestation of Drug Allergy and Hypersensitivity
- The Angiotensin-Converting-Enzyme-Induced Angioedema
- Differential Diagnosis of Chronic Urticaria and Angioedema Based on Molecular Biology, Pharmacology, and Proteomics
- Cutaneous Manifestation of Food Allergy
- IMMUNOLOGYAND ALLERGY CLINICS OF NORTH AMERICA
- FORTHCOMING ISSUES
- May 2017
- August 2017
- November 2017
- RECENT ISSUES
- November 2016
- August 2016
- May 2016
- Foreword: Allergic Skin Disease and the Practicing Allergist: Growing Unmet Need, New Science, and New Treatments
- Preface: Allergic Skin Diseases
- Atopic Dermatitis and Allergic Urticaria
- Key points
- INTRODUCTION
- ATOPIC DERMATITIS
- ALLERGIC URTICARIA
- ALARM SIGNS
- SPECIFIC SYNDROMIC DISEASES GIVING RISE TO ATOPIC DERMATITIS
- Omenn Syndrome
- Atypical Complete DiGeorge Syndrome
- Autosomal-Dominant Hyperimmunoglobulin E with Recurrent Infections Syndrome
- DOCK8 Deficiency
- Wiskott-Aldrich Syndrome
- PGM3 Deficiency
- Immune Dysregulation Polyendocrinopathy Enteropathy X-Linked
- Netherton and Severe Dermatitis-Multiple Allergies-Metabolic Wasting Syndrome
- SPECIFIC DISEASES GIVING RISE TO ALLERGIC URTICARIA
- Phospholipase C?2-Associated Antibody Deficiency
- Vibratory Urticaria due to ADGRE2 Mutations
- Autoinflammatory Syndromes
- SUMMARY
- REFERENCES
- Differential Diagnosis of Atopic Dermatitis
- Key points
- INTRODUCTION
- SEBORRHEIC DERMATITIS
- PSORIASIS
- ALLERGIC CONTACT DERMATITIS
- SCABIES
- MOLLUSCUM DERMATITIS
- TINEA CORPORIS AND TINEA CAPITIS
- MYCOSIS FUNGOIDES
- DERMATOMYOSITIS
- PITYRIASIS LICHENOIDES CHRONICA
- LANGERHANS CELL HISTIOCYTOSIS
- POLYMORPHOUS LIGHT ERUPTION
- ACTINIC PRURIGO
- NUTRITIONAL DEFICIENCY
- SUMMARY
- REFERENCES
- Clinical Measures of Chronic Urticaria
- Key points
- INTRODUCTION
- CLINICAL MEASURES OF CHRONIC SPONTANEOUS URTICARIA AND CHRONIC INDUCIBLE URTICARIAS
- CLINICAL MEASURES OF DISEASE ACTIVITY IN CHRONIC SPONTANEOUS URTICARIA
- Urticaria Activity Score
- Angioedema Activity Score
- CLINICAL MEASURES OF DISEASE ACTIVITY IN CHRONIC INDUCIBLE URTICARIAS
- Cholinergic Urticaria Activity Score
- Critical Trigger Threshold Assessment
- CLINICAL MEASURES OF DISEASE CONTROL
- Urticaria Control Test
- CLINICAL MEASURES OF HEALTH-RELATED QUALITY-OF-LIFE IMPAIRMENT
- Chronic Urticaria Quality of Life Questionnaire
- Angioedema Quality of Life Questionnaire
- SUMMARY
- ACKNOWLEDGMENTS
- REFERENCES
- Current and Future Biomarkers in Atopic Dermatitis
- Key points
- INTRODUCTION
- WHAT ARE BIOMARKERS?
- BIOMARKER TYPES AND THEIR CLINICAL APPLICATION
- WHY ARE BIOMARKERS NEEDED FOR ATOPIC DERMATITIS?
- Biomarkers for Stratification of Patients to Unravel Disease Heterogeneity
- Predicting Treatment Response
- Biomarkers as Objective Measures for Disease Severity
- CURRENT BIOMARKERS IN ATOPIC DERMATITIS
- Diagnostic Biomarkers
- Screening and Prognostic Biomarkers
- Predictive Biomarkers
- Pharmacodynamic Biomarkers
- Monitoring Biomarkers
- FUTURE PERSPECTIVES
- REFERENCES
- The Role of Fungi in Atopic Dermatitis
- Key points
- INTRODUCTION
- EPIDEMIOLOGY
- RISK FACTORS FOR SENSITIZATION TO MALASSEZIA SPP
- Sensitization to Malassezia spp May Correlate with the Severity of Atopic Dermatitis
- Pathophysiology
- Malassezia spp Interacts with the Skin Immune System
- Management and Therapeutic Approaches with Antifungals in Atopic Dermatitis
- REFERENCES
- Infectious Complications in Atopic Dermatitis
- Key points
- INTRODUCTION
- PATHOPHYSIOLOGY OF INFECTIOUS COMPLICATIONS
- Skin Barrier Defects
- Immune Dysregulation
- Skin Microbiome
- BACTERIAL INFECTION
- Staphylococcus aureus
- The Role of Fungi in Atopic Dermatitis
- VIRAL INFECTION
- Eczema Herpeticum
- Eczema Coxsackium
- Eczema Vaccinatum
- Eczema Molluscatum
- MANAGEMENT
- FUTURE CONSIDERATIONS
- REFERENCES
- Biologics in Chronic Urticaria
- Key points
- ANTI-IMMUNOGLOBULIN E MONOCLONAL ANTIBODIES
- Overview and Mechanism of Action of Omalizumab
- Omalizumab Proof-of-Concept and Phase 2 Studies
- Omalizumab Phase 3 Trials
- Omalizumab and Urticaria Guidelines
- Effectiveness of Omalizumab in Other Forms of Urticaria
- Omalizumab in Pregnancy
- Advances in Anti-immunoglobulin E Monoclonal Antibodies
- ANTI-CD20 MONOCLONAL ANTIBODY
- INTRAVENOUS IMMUNOGLOBULIN
- TUMOR NECROSIS FACTOR-a ANTAGONISTS
- INTERLEUKIN-1 ANTAGONISTS
- SUMMARY
- REFERENCES
- Itch in Atopic Dermatitis
- Key points
- INTRODUCTION
- PERIPHERAL ITCH
- Transmission of Peripheral Itch
- Hyperinnervation in Epidermis
- Thermal Hyperalgesia by Artemin
- PRURITOGENS
- Histamine
- Protease and Protease-Activated Receptors and Their Agonists
- Interleukin-31
- Thymic Stromal Lymphopoietin
- Endothelin-1
- CENTRAL ITCH
- Transmission of Itch from the Spinal Cord to the Brain
- Inhibitory Nerve for Itch
- Involvement of Astrocytes in Atopic Itch
- Itch and the Brain
- ASSESSMENT OF CHRONIC ITCH
- ANTIPRURITIC EFFECTS OF CONVENTIONAL TREATMENTS
- RECENT REPORTS ON NEW ANTIPRURITIC DRUGS
- Dupilumab
- Histamine H4 Receptor Antagonist
- Phosphodiesterase 4 Inhibitors
- Anti-Interleukin-31 Receptor Antibody
- The Kappa-Opioid Agonist Nalfurafine
- Topical Tropomyosin Receptor Kinase A Inhibitor
- SUMMARY
- REFERENCES
- Wet Wrap Therapy in Moderate to Severe Atopic Dermatitis
- Key points
- INTRODUCTION
- ROLE OF MULTIDISCIPLINARY CARE
- STEPWISE MANAGEMENT OF ATOPIC DERMATITIS
- ROLE OF WET WRAP THERAPY IN ATOPIC DERMATITIS
- Overview of Wet Wrap Treatment
- Definition of Wet Wrap Therapy
- Mechanism of Wet Wrap Therapy
- Methodology of Wet Wrap Therapy
- Evaluating Studies Using Wet Wrap Therapy
- SUMMARY
- ACKNOWLEDGMENTS
- REFERENCES
- Allergic Contact Dermatitis
- Key points
- INTRODUCTION
- EPIDEMIOLOGY
- PATHOMECHANISM
- CLINICAL FEATURES
- DIFFERENTIAL DIAGNOSES
- DIAGNOSIS
- PATCH TEST
- LIMITATIONS OF PATCH TESTING
- SURVEY OF PATCH TEST REACTIONS VIA DIGITAL IMAGING
- MODIFICATIONS OF PATCH TESTING
- IN VITRO TESTS
- TREATMENT
- CURRENT CONTROVERSIES
- REFERENCES
- Mastocytosis and Anaphylaxis
- Key points
- INTRODUCTION
- EPIDEMIOLOGY
- Prevalence of Mastocytosis
- Prevalence of Atopy and Allergy in Mastocytosis
- Prevalence of Anaphylaxis in General Population
- Prevalence of Anaphylaxis in Patients with Mastocytosis
- RISK FACTORS FOR ANAPHYLAXIS IN PATIENTS WITH MASTOCYTOSIS
- PATHOPHYSIOLOGY
- CLINICAL FEATURES
- TRIGGERS OF ANAPHYLAXIS IN MASTOCYTOSIS
- Hymenoptera Venom Anaphylaxis in Mastocytosis
- Idiopathic Anaphylaxis in Mastocytosis
- Food Anaphylaxis in Mastocytosis
- Anaphylaxis Caused by Drugs
- Anaphylaxis in the Context of Mast Cell Activation Syndrome
- ACUTE MANAGEMENT
- CHRONIC MANAGEMENT
- Emergency Preparedness
- Venom Immunotherapy in Mastocytosis
- Anesthesia in Patients with Mastocytosis
- Further Treatment Options for Severe Cases of Recurrent Anaphylaxis
- REFERENCES
- Cutaneous Manifestation of Drug Allergy and Hypersensitivity
- Key points
- INTRODUCTION
- Allergic and Nonallergic Drug Hypersensitivity
- Urticaria, Angioedema, and Anaphylaxis
- Skin eruption
- Cutaneous histopathology
- Underlying mechanisms
- Erythematous Eruptions
- Skin eruptions
- Cutaneous histopathology
- Underlying mechanisms
- Pustular Eruptions
- Skin eruptions
- Cutaneous histopathology
- Underlying mechanisms
- Acute Generalized Exanthematous Pustulosis
- Skin eruptions
- Cutaneous histopathology
- Underlying mechanisms
- Bullous Eruptions
- Pseudoporphyria
- Skin eruption
- Cutaneous histopathology
- Underlying Mechanisms
- Drug-Induced Linear Immunoglobulin A Bullous Diseases
- Skin eruptions
- Cutaneous histopathology
- Underlying mechanisms
- Drug-Induced Pemphigus
- Skin eruption
- Cutaneous histopathology
- Underlying mechanisms
- Drug-Induced Bullous Pemphigoid
- Skin eruptions
- Cutaneous histopathology
- Underlying mechanisms
- Lichenoid Eruptions
- Skin eruption
- Cutaneous histopathology
- Underlying mechanisms
- Cutaneous Pseudolymphoma Reaction
- Skin eruptions
- Cutaneous histopathology
- Underlying mechanisms
- Drug-Induced Vasculitis
- Skin eruption
- Cutaneous histopathology
- Underlying Mechanisms
- Drug-Induced Lupus
- Skin eruption
- Cutaneous histopathology
- Underlying mechanisms
- Allergic Contact Dermatitis to Drugs
- Skin eruptions
- Cutaneous histopathology
- Underlying mechanisms
- Photoallergic Dermatitis to Drugs
- Skin eruptions
- Underlying Mechanism
- Phototoxic Reactions
- Skin eruption
- Cutaneous histopathology
- Underlying mechanisms
- Fixed Drug Eruption
- Skin eruptions
- Cutaneous histopathology
- Underlying mechanisms
- Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis
- Skin eruption and organ involvement
- Cutaneous histopathology
- Underlying mechanisms
- Drug Reaction with Eosinophilia and Systemic Symptoms
- Skin eruption and organ involvement
- Cutaneous histopathology
- Underlying mechanisms
- SUMMARY
- REFERENCES
- The Angiotensin-Converting-Enzyme-Induced Angioedema
- Key points
- ETIOLOGY AND PATHOPHYSIOLOGY OF ANGIOEDEMA
- BRADYKININ RECEPTORS
- BRADYKININ EFFECTS
- BRADYKININ-INDUCED ANGIOEDEMA
- Hereditary Angioedema
- Trigger Factors
- IATROGENIC INDUCED BRADYKININ ANGIOEDEMA
- ANGIOTENSIN-CONVERTING ENZYME INHIBITOR-INDUCED ANGIOEDEMA
- ANGIOTENSIN-1 BLOCKER-INDUCED ANGIOEDEMA
- RENIN INHIBITOR-INDUCED ANGIOEDEMA
- ACQUIRED ANGIOEDEMA
- THERAPY OF THE ACUTE ANGIOTENSIN-CONVERTING ENZYME INHIBITOR-INDUCED ANGIOEDEMA
- Mechanical Protection of the Airways
- Forms of Mechanical Safeguarding
- Supportive Procedures in the Therapy
- Symptomatic Pharmacotherapy
- Nonspecific Pharmacotherapy
- Corticosteroids
- SPECIFIC PHARMACOTHERAPY
- Icatibant
- C1 INHIBITOR
- SUMMARY
- REFERENCES
- Differential Diagnosis of Chronic Urticaria and Angioedema Based on Molecular Biology, Pharmacology, and Proteomics
- Key points
- INTRODUCTION
- TRADITIONAL SCHEMES OF CLASSIFICATION OF CHRONIC URTICARIA BASED ON DISEASE PHENOTYPE AND THEIR LIMITATIONS IN DIFFERENTIAL ...
- DIFFERENTIAL DIAGNOSIS OF CHRONIC URTICARIA AND ANGIOEDEMA SHOULD INCORPORATE TERMS DERIVED FROM ADVANCES IN MOLECULAR BIOL ...
- DIFFERENTIAL DIAGNOSIS OF URTICARIA AND ANGIOEDEMA SHOULD INCLUDE PHARMACOLOGIC INFORMATION INDICATING RESPONSE TO THERAPY
- DIFFERENTIAL DIAGNOSIS OF URTICARIA AND ANGIOEDEMA SHOULD INCLUDE INFORMATION FROM NOVEL PROTEOMIC TECHNOLOGY
- DIFFERENTIAL DIAGNOSIS OF CHRONIC URTICARIA AND ANGIOEDEMA SHOULD INCLUDE MECHANISMS IDENTIFIED IN OTHER SYSTEMIC AUTOIMMUN ...
- SUMMARY
- ACKNOWLEDGMENTS
- REFERENCES
- Cutaneous Manifestation of Food Allergy
- Key points
- URTICARIA
- CONTACT URTICARIA
- CONTACT DERMATITIS
- ATOPIC DERMATITIS
- Food-specific IgE in Atopic Dermatitis
- Evaluations of Food Exacerbating Atopic Dermatitis
- Immunopathology of Food and Atopic Dermatitis
- Elimination Diets in Atopic Dermatitis
- SUMMARY
- REFERENCES
