
The New Prescriber
Beschreibung
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Take an evidence-based approach to prescribing decisions with this comprehensive guide
Prescribing decisions are among the most important parts of clinical practice. Balancing patient needs, possible drug interactions, the probability of adverse drug reactions, and more requires an evidence-based approach rooted in pharmacological principles. The New Prescriber: An Integrated Approach to Medical and Non-medical Prescribing offers a thorough, accessible introduction to the core components of prescribing, essential for any student preparing for clinical practice. Now fully updated to reflect the latest best practices and to address questions raised by different prescribing settings, it promises to continue as the key introduction to this vital subject.
Readers of the second edition of The New Prescriber will also find:
- An introduction to the principles of pharmacodynamics and pharmacokinetics
- New sections covering topics including illegal and illicit drugs, overdose and deprescribing, and more
- A thorough glossary with key terms
The New Prescriber is ideal for all non-medical prescribing students, nursing, allied health professionals, and medical students.
Weitere Details
Weitere Ausgaben
Andere Ausgaben

Personen
Joanne Lymn is Professor of Healthcare Education at University of Nottingham, UK, and a National Teaching Fellow.
Alison Mostyn is Professor of Pharmacology Education for Health and Director of Teaching and Learning, University of Nottingham, UK.
Roger Knaggs is Professor of Pain Management at University of Nottingham, UK, and Specialist Pharmacist in Pain Management at Primary Integrated Community Services. He is also President of the British Pain Society.
Michael Randall is Professor of Pharmacology at University of Nottingham, UK, and a Fellow of the British Pharmacological Society.
Dianne Bowskill is Associate Professor of Prescribing Education and Lead for Non-medical prescribing, University of Nottingham, UK.
Inhalt
List of Contributors xxvi
Foreword xxvii
Preface xxviii
Acknowledgements xxix
Section 1 The Patient 1
Section Introduction 1
1 The Consultation 3
Frank Coffey and Dianne Bowskill
2 Accountability and Prescribing 14
Matthew Boyd, Stephanie Bridges, and Helen Boardman
3 Prescribing and the Law 23
Richard Griffith
4 The Ethics of Prescribing 36
Matthew Boyd, Stephanie Bridges, and Helen Boardman
5 Prescribing in Practice 44
Dianne Bowskill and Daniel Shipley
6 Public Health Issues 53
Michael Watson and Katharine Whittingham
Section 2 Pharmacology 63
Section Introduction 65
7 General Principles of Pharmacology 67
Joanne Lymn and Alison Mostyn
8 Pharmacokinetics 1: Absorption and Distribution 79
Joanne Lymn and Alison Mostyn
9 Pharmacokinetics 2: Metabolism and Excretion 92
Joanne Lymn and Alison Mostyn
10 Routes of Administration 106
Joanne Lymn and Roger Knaggs
11 Variations in Drug Handling 114
Michael Randall
12 Polypharmacy and Medicines Optimisation 124
Daniel Shipley
13 Adverse Drug Reactions and Interactions 134
Alison Mostyn and Daniel Shipley
14 Introduction to the Autonomic Nervous System 144
Joanne Lymn
15 Clinical Application of the Principles of the Autonomic Nervous Systems 157
Joanne Lymn
16 The Gastrointestinal System 167
Michael Randall
17 Cardiovascular Drugs and Diseases 177
Richard Roberts
18 Haemostasis and Thrombosis 196
Michael Randall
19 The Renal System 208
Michael Randall
20 The Respiratory System 221
Richard Roberts
21 Introduction to the Central Nervous System 235
Yvonne Mbaki
22 Neurodegenerative Disorders 245
David Kendall
23 Depression and Anxiety 256
Yvonne Mbaki
24 Schizophrenia 267
David Kendall
25 Epilepsy and Antiseizure Drugs 277
Michael F O'Donoghue and Christina Giavasi
26 Pain and Analgesia 293
Roger Knaggs
27 Drugs of Misuse 308
Michael Randall
28 Antibacterial Chemotherapy 315
Tim Hills
29 Antibiotic Resistance and Clostridioides Difficile 331
Tim Hills
30 Antifungal and Antiviral Drugs 342
Tim Hills
31 The Endocrine System 352
Alison Mostyn and Daniel Shipley
32 Contraception and Reproductive Health 369
Alison Mostyn and Anna Soames
33 Cancer Pharmacotherapy 381
Michael Randall
34 Musculoskeletal Disease 392
Sana Awan and David Andrew Walsh
Glossary 409
Activity Answers 417
Index 445
CHAPTER 1
The Consultation
Frank Coffey and Dianne Bowskill
LEARNING OUTCOMES
By the end of this chapter the reader should be able to:
- recognise and analyse the important elements of a consultation
- identify the components of the traditional medical history
- appreciate the diagnostic process and distinguish between the treatment of symptoms and the treatment of a disease or condition
- identify the elements of the consultation essential for safe prescribing (bottom liners)
- refine their professional assessment/consultation for the prescribing role
- have insight into the impact of technological advances on assessment, diagnosis and treatment.
As you begin your prescribing education you already have a wealth of professional experience in your own area of practice. The assessment and consultation skills learnt as part of professional registration are well practised but may need to be refined as you take on prescribing. We are not suggesting that you need to adopt a new or medical model of consultation, although this might be desirable in certain advanced practice roles. For the majority of new prescribers, the focus will be on analysing their current framework of assessment or consultation and identifying adaptations required to support prescribing decisions. In this chapter we will ask you to think about the elements of the consultation that you may need to adapt or work on. We will give practice tips and point out common errors that can affect the quality of a consultation.
Prescribing inherently brings with it a greater requirement to make a diagnosis. This responsibility may be new and quite daunting. Prescribers need to understand the diagnostic process. In most circumstances, the key factor for accurate diagnosis is eliciting a good history. For this reason, we will look in detail at the elements of a history. Examination and investigations are directed by and supplement the history. The depth and focus of the history and examination will vary depending on the setting and your role. Wherever you work, however, it is essential to be thorough and systematic, and above all to know the bounds of your competence. History taking, examination and clinical decision making are skills that need to be continuously practiced under expert supervision.
Ideally your prescribing will be effective, but above all it should be safe. The primary dictum of all healthcare practice is 'primum non nocere' (above all do no harm). We will outline the elements of the consultation that are essential for safe prescribing, the 'bottom liners' of a prescribing consultation.
In the final part of the chapter, we will explore the potential impact of technological and scientific advances on assessment and clinical decision making and outline the increasing emphasis on health improvement and prevention in consultations.
THE CONSULTATION
The consultation is a two-way interaction between a healthcare practitioner and a patient. Your role will influence the types of patients you treat, the environment in which you see them and your approach to the consultation. As a non-medical prescriber your focus is on diagnosis. Assessment for diagnosis in a typical consultation comprises the history, examination and investigations. Factors to consider include the urgency and seriousness of the presentation, time constraints and the personalities, culture, language and medical knowledge of both the patient and the clinician. Previous contact with the patient, autonomy, and confidence are further influences on the consultation. Communication and consultation skills are inextricably interlinked. There are many excellent textbooks available for prescribers who wish to enhance their communication skills (Brown et al. 2016; Silverman et al. 1998; Berry 2004).
ELEMENTS OF A CONSULTATION
Although consultations differ in specifics, there are common elements and generic skills that are applicable in varying degrees to any given situation. Numerous consultation models have been developed over the years, for example Neighbour (2005), Pendleton et al. (2003) and Calgary Cambridge in Silverman et al. (1998). Rather than dwelling on the theory underpinning consultations, we will describe a practical framework for the consultation (see Box 1.1). This includes an assessment component (see I to (j) in Box 1.1) and other elements which can be applied in varying degrees to all consultations.
It is important for consultations to have a degree of structure. The skill in consulting is to maintain a structure and system that includes all the vital elements and yet does not feel like a straitjacket for the patient or clinician. In the following section we will analyse the different elements of the consultation in more detail and highlight those that are likely to change or need more emphasis for you as you take on prescribing.
BOX 1.1 ELEMENTS OF A CONSULTATION
- Preparing for the consultation and setting goals for it.
- Establishing an initial rapport with the patient.
- Identifying the reason(s) for the consultation.
- Exploring the patient's problem(s) and ascertaining their ideas, concerns and expectations about it.
- Focusing questions to obtain essential information.
- Gathering sufficient information relating to the patient's social and psychological circumstances to ascertain their impact.
- Coming up with a diagnosis or a number of differential diagnoses in order of likelihood.
- Performing a focused physical examination and near-patient tests to support or refute the differential diagnoses.
- Reaching a shared understanding of the problem with the patient.
- Interpreting the information gathered and re-evaluating the problem.
- Considering further investigations if necessary.
- Deciding what treatment options, pharmacological and non-pharmacological, are available.
- Advising the patient about actions needed to tackle the problem.
- Explaining these actions and the time of follow-up if required.
- Inviting and answering any questions.
- Summarising for the patient and terminating the consultation.
- Making a written record of the consultation.
- Presenting your findings to another health professional.
STOP AND THINK
Using Box 1.1 as a framework, reflect on your current consultations and identify elements you are less confident with. Make a note of these to inform learning and development needs.
(A) PREPARING FOR THE CONSULTATION AND SETTING GOALS
Take time to study all the information available to you about the patient prior to the consultation. Study referral letters and available medical records for vital information, including the patient's past history, medications and allergies. Set goals for the consultation and ensure that the environment is set up appropriately with adequate lighting and privacy.
(B) ESTABLISHING THE INITIAL RAPPORT
First impressions are especially important and will influence your subsequent relationship with the patient. If you have not encountered the patient before, introduce yourself by name and explain your role. Check the patient's details (name, date of birth, address). Observe the patient's demeanour and physical appearance. The patient will invariably be feeling nervous. Put them at ease by projecting confidence and warmth, and they are more likely to open up to you during the consultation.
(C) TO (G) HISTORY TAKING/DIAGNOSIS HYPOTHESIS
Elements (c) to (g) in Box 1.1 are primarily concerned with the taking of a history and the consideration of differential diagnoses. The importance of the history cannot be overstated. In the vast majority of cases (>70%) the history will provide an accurate diagnosis or differential diagnosis even before the examination and investigations are performed. A good history will therefore facilitate effective prescribing. Certain minimum information must be elicited to ensure safe prescribing,
The history is a two-way process. In reality, we do not 'take' a history. Rather, we 'make' a history with the patient. The result is influenced by both the practitioner's and the patient's prior knowledge, experiences and understanding of language. Where understanding of language is a barrier, clinical risk is significantly increased and an interpreter should be considered. There are psychodynamic processes at play during any consultation which the practitioner needs to be aware of. These are explored in detail in other publications (Berry 2004).
The scope and depth of the history will depend on the role of the practitioner and the circumstances surrounding the consultation. Whatever the nature of the history, it is essential to be systematic and as far as possible follow the same sequence of questioning each time. In this way vital information will not be overlooked. This becomes particularly important when the patient has multiple symptoms and/or a complicated medical history.
Most patient histories will contain some or all the elements of a traditional medical history. This structure has limitations and has been criticised for being practitioner...
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