1 Quality Assurance in Environmental Trace Analysis.- 1. The Quality Assurance Program.- 2. Quality Control Procedures in the Quality Assurance Program.- 3. Operation of a Quality Assurance Program.- References.- 2 Applications of HPLC to the Analysis of Polycyclic Aromatic Hydrocarbons in Environmental Samples.- 1. Introduction.- 2. Nomenclature, Structure, and Carcinogenicity.- 3. Origin and Formation in the Environment.- 4. Methods of Analysis for Polycyclic Hydrocarbons.- 5. HPLC Applications in PAH Analysis.- 6. Conclusions.- References.- 3 HPLC of Pesticide Residues in Environmental Samples.- 1. Introduction.- 2. Instrumentation and Methodology.- 3. Applications.- 4. Conclusions.- References.- 4 HPLC Determination of Surfactants and Related Compounds.- 1. Anionic Surfactants and Related Compounds.- 2. Nonionic Surfactants.- 3. Cationic and Amphoteric Surfactants and Related Compounds.- References.- 5 Trace Metal Analysis by High Performance Liquid Chromatography.- 1. Introduction.- 2. HPLC-Ultraviolet, -Visible, and/or -Fluorescence Detection of Metal Species.- 3. HPLC-Mass Spectrometric Detection of Metal Species.- 4. HPLC-Atomic Absorption Spectroscopic Detection of Metal Species.- 5. HPLC-Atomic Fluorescence Spectroscopic Detection of Metal Species.- 6. HPLC-Inductively Coupled or -Direct-Current Plasma Emission Spectroscopic Detection of Metal Species.- 7. HPLC-Electrochemical and -Conductivity Detection of Metal Species.- 8. Ion Chromatography-Conductivity Detection of Metal Species.- 9. Conclusions.- References.- 6 Anion Analysis by Ion Chromatography.- 1. Introduction.- 2. Separation Modes.- 3. Detection Modes.- 4. New Applications in Anion Ion Chromatography.- 5. Summary.- References.- 7 HPLC Sample Injection and Column Switching.- 1.HPLC Sample Injection Using Valves.- 2. HPLC Column Switching.- References.- 8 High Performance Liquid Chromatography as a Cleanup Technique.- 1. Introduction.- 2. Cleanup for Gas Chromatography (GC) with Electron Capture (EC) or Flame Detection.- 3. Cleanup for GC-Mass Spectrometry (MS).- 4. HPLC-HPLC.- 5. Cleanup for Radioimmunoassay (RIA).- 6. Radioisotope Fractionation.- 7. Summary.- References.