
Rheumatic Diseases in Older Adults, An Issue of Clinics in Geriatric Medicine
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Inhalt
- Front Cover
- Rheumatic Diseasesin Older Adults
- Copyright
- Contributors
- EDITORS
- AUTHORS
- Contents
- Preface: Rheumatic Diseases in Older Adults
- Pharmacotherapy Pearls for the Geriatrician: Focus on Oral Disease-Modifying Antirheumatic Drugs Including Newer Agents
- Pathogenesis and Management of Sarcopenia
- A Review of Osteoporosis in the Older Adult
- Nonsurgical Management of Osteoarthritis Knee Pain in the Older Adult
- Regional Rheumatic Disorders and Rehabilitation in Older Adults
- Rheumatologic Manifestations of Malignancy
- Sjögren Syndrome and Other Causes of Sicca in Older Adults
- Cardiovascular Disease Risk in Patients with Rheumatic Diseases
- Gaps in Aging Research as it Applies to Rheumatologic Clinical Care
- Update on Crystal-Induced Arthritides
- CLINICS IN GERIATRIC MEDICINE
- FORTHCOMING ISSUES
- May 2017
- August 2017
- November 2017
- RECENT ISSUES
- November 2016
- August 2016
- May 2016
- Preface: Rheumatic Diseases in Older Adults
- REFERENCES
- Pharmacotherapy Pearls for the Geriatrician
- Key points
- INTRODUCTION
- AGE-RELATED CHANGES IN DRUG METABOLISM
- POLYPHARMACY
- HEALTH LITERACY
- AGE BIAS
- METHOTREXATE
- HYDROXYCHLOROQUINE
- SULFASALAZINE
- LEFLUNOMIDE
- TOFACITINIB
- SPECIAL CONSIDERATIONS
- SUMMARY
- ACKNOWLEDGMENTS
- REFERENCES
- Pathogenesis and Management of Sarcopenia
- Key points
- INTRODUCTION
- EPIDEMIOLOGY
- RISK FACTORS
- Lifestyle Lacking Exercise
- Hormone and Cytokine Imbalance
- Protein Synthesis and Regeneration
- Motor Unit Remodelling
- Evolutionary Basis
- Early Developmental Influences
- DIAGNOSING SARCOPENIA
- SARCOPENIA HISTOPATHOLOGY
- MANAGEMENT
- Nonpharmacologic Treatment
- Pharmacological Therapies
- Herbal Supplements and Nutrition
- SECONDARY SARCOPENIA
- Cachexia
- Frailty
- Sarcopenic Obesity
- SUMMARY AND FUTURE DIRECTION
- REFERENCES
- A Review of Osteoporosis in the Older Adult
- Key points
- INTRODUCTION
- SUMMARY
- REFERENCES
- Nonsurgical Management of Osteoarthritis Knee Pain in the Older Adult
- Key points
- INTRODUCTION
- NONPHARMACOLOGIC TREATMENT OPTIONS
- WEIGHT LOSS
- EXERCISE
- Pharmacologic Intervention: Key Points
- TOPICAL THERAPIES
- Topical Nonsteroidal Anti-inflammatory Agents
- Capsaicin
- Intra-articular Corticosteroid Injections
- Intra-articular Hyaluronic Acid Injections
- ORAL THERAPIES
- Nonsteroidal Anti-inflammatory Drugs
- Acetaminophen
- Glucosamine and Chondroitin
- Tramadol and Other Opioids
- SUMMARY
- REFERENCES
- Regional Rheumatic Disorders and Rehabilitation in Older Adults
- Key points
- INTRODUCTION
- WHAT IS A REGIONAL RHEUMATIC DISORDER?
- PATIENT EVALUATION CONSIDERATIONS
- REHABILITATION MEDICINE HISTORY
- PHYSICAL EXAMINATION
- SUPPLEMENTARY WORK-UP
- COMMON REGIONAL RHEUMATIC PAIN SYNDROMES
- Bursae Disorders
- Ligamentous injuries
- Muscle or tendon injuries
- SPECIFIC TESTS
- OUTCOME MEASURES
- ADDRESSING AND DOCUMENTING THE NEED FOR PHYSICAL REHABILITATION
- THE PHILOSOPHY OF PHYSICAL REHABILITATION
- GENERAL CONSIDERATIONS IN GERIATRIC REHABILITATION
- Aging is a heterogeneous process
- Older Adults Commonly Have Multiple Chronic Conditions
- Older Adults Have Unique Psychosocial Needs
- Physical Rehabilitation Efforts Should Focus On Function
- THE PLAN OF CARE
- Goal Setting
- NONINVASIVE PROCEDURAL INTERVENTIONS
- PATIENT EDUCATION
- Joint Protection
- Energy Conservation
- Environmental Adaptations
- INVASIVE PHYSIATRIC INTERVENTIONS
- Acupuncture/Dry Needling
- Intra-articular Injections
- Viscohyaluronic Acid
- Regenerative Injections
- Prolotherapy
- Platelet-rich Plasma
- Soft Tissue Injections
- Ultrasonography-guided Needle Fenestration/Tenotomy
- FUTURE RESEARCH CONSIDERATIONS
- REFERENCES
- Rheumatologic Manifestations of Malignancy
- Key points
- INTRODUCTION
- CLINICAL CLUES FOR PRESENCE OF AN OCCULT MALIGNANCY
- SPECTRUM OF RHEUMATOLOGIC MANIFESTATIONS OF MALIGNANCIES
- Primary or Metastatic Tumors Involving the Bone, Joint, Muscles, or Associated Structures
- Increased Risk of Malignancies in Certain Autoimmune Rheumatologic Conditions
- Rheumatoid arthritis
- Systemic lupus erythematosus
- Systemic sclerosis and myositis
- Inflammatory myopathies
- Vasculitides
- Paraneoplastic Musculoskeletal Syndromes
- Hypertrophic osteoarthropathy
- Paraneoplastic polyarthritis
- Palmar fasciitis and polyarthritis syndrome
- Remitting seronegative symmetric synovitis with pitting edema (RS3PE)
- Multicentric reticulohistiocytosis (MRH)
- Erythromelalgia
- Sweet syndrome (acute febrile neutrophilic dermatosis)
- Canale-Smith stiff-person or stiff-man syndrome
- Tumor-induced osteomalacia or oncogenic osteomalacia
- Polyneuropathy, organomegaly, endocrinopathy, monoclonal protein, skin changes (POEMS) syndrome
- Eosinophilic fasciitis
- Lupus-like syndromes
- Polymyalgia rheumatica-like syndrome
- Pyogenic arthritis
- SUMMARY
- REFERENCES
- Sjögren Syndrome and Other Causes of Sicca in Older Adults
- Key points
- INTRODUCTION
- DRY EYE
- XEROSTOMIA AND SALIVARY HYPOFUNCTION
- VAGINAL DRYNESS
- SJÖGREN SYNDROME
- DIAGNOSIS OF SJÖGREN SYNDROME
- MANAGEMENT OF SJÖGREN SYNDROME
- SUMMARY
- REFERENCES
- Cardiovascular Disease Risk in Patients with Rheumatic Diseases
- Key points
- INTRODUCTION
- WHAT EXPLAINS THE EXCESS CARDIOVASCULAR DISEASE RISK IN RHEUMATOID ARTHRITIS?
- ROLE OF DYSLIPIDEMIA IN CARDIOVASCULAR DISEASE RISK IN RHEUMATOID ARTHRITIS
- Can Lipoprotein Particle Concentrations Explain the Lipid Paradox in Rheumatoid Arthritis?
- Current Risk Factors in Rheumatoid Arthritis Patients Underestimate Prior Exposures and Burden of Atherosclerosis
- Substantially Increased Burden of Atherosclerosis at Diagnosis of Rheumatoid Arthritis?
- Inflammation May Cause Myocardial Disease Directly, Leading to Heart Failure
- Emergence of Rheumatoid Arthritis Disease Activity as Key Predictor and Target for Prevention of Cardiovascular Disease Risk
- SUMMARY
- REFERENCES
- Gaps in Aging Research as it Applies to Rheumatologic Clinical Care
- Key points
- GAPS/CHALLENGES IN CURRENT GERIATRIC RHEUMATOLOGY CLINICAL CARE
- Gaps in Understanding of the Biology of Aging
- Adaptation to stress
- Epigenetics
- Inflammation or inflammaging
- Macromolecular damage/oxidative stress injury
- Metabolic pathways
- Proteostasis
- Stem cell regeneration
- Gaps in Assessment and Outcome Measurement
- Prognostication, goal setting, and time horizons in older adults
- Patient-reported outcomes in older adults
- Gaps in Managing/Treating Older Adults with Rheumatologic Conditions
- Multimorbidity and polypharmacy
- Individualized interdisciplinary management
- Immunizations
- BRIDGING THE GAP: A CALL TO ACTION
- REFERENCES
- Update on Crystal-Induced Arthritides
- Key points
- INTRODUCTION
- GOUT PRESENTATION IN THE GERIATRIC POPULATION CAN DIFFER FROM CLASSIC GOUT SEEN IN MIDDLE-AGED MEN
- TREATMENT OF GOUT
- MANAGEMENT OF ACUTE GOUT ATTACKS
- PROPHYLACTIC ANTIINFLAMMATORY THERAPY FOR PATIENTS WITH GOUT
- URATE-LOWERING THERAPY
- SUMMARY
- REFERENCES
- Index
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