Rheumatic Diseases in Older Adults, An Issue of Clinics in Geriatric Medicine

Name: Rheumatic Diseases in Older Adults, An Issue of Clinics in Geriatric Medicine
Brand: Elsevier
Price: 66.99 EUR
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James D. Katz Brian Walitt(Autor*in)

Elsevier (Verlag)

1. Auflage

Erschienen am 24. November 2016

100 Seiten

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Front Cover
Rheumatic Diseasesin Older Adults
Copyright
Contributors
EDITORS
AUTHORS
Contents
Preface: Rheumatic Diseases in Older Adults
Pharmacotherapy Pearls for the Geriatrician: Focus on Oral Disease-Modifying Antirheumatic Drugs Including Newer Agents
Pathogenesis and Management of Sarcopenia
A Review of Osteoporosis in the Older Adult
Nonsurgical Management of Osteoarthritis Knee Pain in the Older Adult
Regional Rheumatic Disorders and Rehabilitation in Older Adults
Rheumatologic Manifestations of Malignancy
Sjögren Syndrome and Other Causes of Sicca in Older Adults
Cardiovascular Disease Risk in Patients with Rheumatic Diseases
Gaps in Aging Research as it Applies to Rheumatologic Clinical Care
Update on Crystal-Induced Arthritides
CLINICS IN GERIATRIC MEDICINE
FORTHCOMING ISSUES
May 2017
August 2017
November 2017
RECENT ISSUES
November 2016
August 2016
May 2016
Preface: Rheumatic Diseases in Older Adults
REFERENCES
Pharmacotherapy Pearls for the Geriatrician
Key points
INTRODUCTION
AGE-RELATED CHANGES IN DRUG METABOLISM
POLYPHARMACY
HEALTH LITERACY
AGE BIAS
METHOTREXATE
HYDROXYCHLOROQUINE
SULFASALAZINE
LEFLUNOMIDE
TOFACITINIB
SPECIAL CONSIDERATIONS
SUMMARY
ACKNOWLEDGMENTS
REFERENCES
Pathogenesis and Management of Sarcopenia
Key points
INTRODUCTION
EPIDEMIOLOGY
RISK FACTORS
Lifestyle Lacking Exercise
Hormone and Cytokine Imbalance
Protein Synthesis and Regeneration
Motor Unit Remodelling
Evolutionary Basis
Early Developmental Influences
DIAGNOSING SARCOPENIA
SARCOPENIA HISTOPATHOLOGY
MANAGEMENT
Nonpharmacologic Treatment
Pharmacological Therapies
Herbal Supplements and Nutrition
SECONDARY SARCOPENIA
Cachexia
Frailty
Sarcopenic Obesity
SUMMARY AND FUTURE DIRECTION
REFERENCES
A Review of Osteoporosis in the Older Adult
Key points
INTRODUCTION
SUMMARY
REFERENCES
Nonsurgical Management of Osteoarthritis Knee Pain in the Older Adult
Key points
INTRODUCTION
NONPHARMACOLOGIC TREATMENT OPTIONS
WEIGHT LOSS
EXERCISE
Pharmacologic Intervention: Key Points
TOPICAL THERAPIES
Topical Nonsteroidal Anti-inflammatory Agents
Capsaicin
Intra-articular Corticosteroid Injections
Intra-articular Hyaluronic Acid Injections
ORAL THERAPIES
Nonsteroidal Anti-inflammatory Drugs
Acetaminophen
Glucosamine and Chondroitin
Tramadol and Other Opioids
SUMMARY
REFERENCES
Regional Rheumatic Disorders and Rehabilitation in Older Adults
Key points
INTRODUCTION
WHAT IS A REGIONAL RHEUMATIC DISORDER?
PATIENT EVALUATION CONSIDERATIONS
REHABILITATION MEDICINE HISTORY
PHYSICAL EXAMINATION
SUPPLEMENTARY WORK-UP
COMMON REGIONAL RHEUMATIC PAIN SYNDROMES
Bursae Disorders
Ligamentous injuries
Muscle or tendon injuries
SPECIFIC TESTS
OUTCOME MEASURES
ADDRESSING AND DOCUMENTING THE NEED FOR PHYSICAL REHABILITATION
THE PHILOSOPHY OF PHYSICAL REHABILITATION
GENERAL CONSIDERATIONS IN GERIATRIC REHABILITATION
Aging is a heterogeneous process
Older Adults Commonly Have Multiple Chronic Conditions
Older Adults Have Unique Psychosocial Needs
Physical Rehabilitation Efforts Should Focus On Function
THE PLAN OF CARE
Goal Setting
NONINVASIVE PROCEDURAL INTERVENTIONS
PATIENT EDUCATION
Joint Protection
Energy Conservation
Environmental Adaptations
INVASIVE PHYSIATRIC INTERVENTIONS
Acupuncture/Dry Needling
Intra-articular Injections
Viscohyaluronic Acid
Regenerative Injections
Prolotherapy
Platelet-rich Plasma
Soft Tissue Injections
Ultrasonography-guided Needle Fenestration/Tenotomy
FUTURE RESEARCH CONSIDERATIONS
REFERENCES
Rheumatologic Manifestations of Malignancy
Key points
INTRODUCTION
CLINICAL CLUES FOR PRESENCE OF AN OCCULT MALIGNANCY
SPECTRUM OF RHEUMATOLOGIC MANIFESTATIONS OF MALIGNANCIES
Primary or Metastatic Tumors Involving the Bone, Joint, Muscles, or Associated Structures
Increased Risk of Malignancies in Certain Autoimmune Rheumatologic Conditions
Rheumatoid arthritis
Systemic lupus erythematosus
Systemic sclerosis and myositis
Inflammatory myopathies
Vasculitides
Paraneoplastic Musculoskeletal Syndromes
Hypertrophic osteoarthropathy
Paraneoplastic polyarthritis
Palmar fasciitis and polyarthritis syndrome
Remitting seronegative symmetric synovitis with pitting edema (RS3PE)
Multicentric reticulohistiocytosis (MRH)
Erythromelalgia
Sweet syndrome (acute febrile neutrophilic dermatosis)
Canale-Smith stiff-person or stiff-man syndrome
Tumor-induced osteomalacia or oncogenic osteomalacia
Polyneuropathy, organomegaly, endocrinopathy, monoclonal protein, skin changes (POEMS) syndrome
Eosinophilic fasciitis
Lupus-like syndromes
Polymyalgia rheumatica-like syndrome
Pyogenic arthritis
SUMMARY
REFERENCES
Sjögren Syndrome and Other Causes of Sicca in Older Adults
Key points
INTRODUCTION
DRY EYE
XEROSTOMIA AND SALIVARY HYPOFUNCTION
VAGINAL DRYNESS
SJÖGREN SYNDROME
DIAGNOSIS OF SJÖGREN SYNDROME
MANAGEMENT OF SJÖGREN SYNDROME
SUMMARY
REFERENCES
Cardiovascular Disease Risk in Patients with Rheumatic Diseases
Key points
INTRODUCTION
WHAT EXPLAINS THE EXCESS CARDIOVASCULAR DISEASE RISK IN RHEUMATOID ARTHRITIS?
ROLE OF DYSLIPIDEMIA IN CARDIOVASCULAR DISEASE RISK IN RHEUMATOID ARTHRITIS
Can Lipoprotein Particle Concentrations Explain the Lipid Paradox in Rheumatoid Arthritis?
Current Risk Factors in Rheumatoid Arthritis Patients Underestimate Prior Exposures and Burden of Atherosclerosis
Substantially Increased Burden of Atherosclerosis at Diagnosis of Rheumatoid Arthritis?
Inflammation May Cause Myocardial Disease Directly, Leading to Heart Failure
Emergence of Rheumatoid Arthritis Disease Activity as Key Predictor and Target for Prevention of Cardiovascular Disease Risk
SUMMARY
REFERENCES
Gaps in Aging Research as it Applies to Rheumatologic Clinical Care
Key points
GAPS/CHALLENGES IN CURRENT GERIATRIC RHEUMATOLOGY CLINICAL CARE
Gaps in Understanding of the Biology of Aging
Adaptation to stress
Epigenetics
Inflammation or inflammaging
Macromolecular damage/oxidative stress injury
Metabolic pathways
Proteostasis
Stem cell regeneration
Gaps in Assessment and Outcome Measurement
Prognostication, goal setting, and time horizons in older adults
Patient-reported outcomes in older adults
Gaps in Managing/Treating Older Adults with Rheumatologic Conditions
Multimorbidity and polypharmacy
Individualized interdisciplinary management
Immunizations
BRIDGING THE GAP: A CALL TO ACTION
REFERENCES
Update on Crystal-Induced Arthritides
Key points
INTRODUCTION
GOUT PRESENTATION IN THE GERIATRIC POPULATION CAN DIFFER FROM CLASSIC GOUT SEEN IN MIDDLE-AGED MEN
TREATMENT OF GOUT
MANAGEMENT OF ACUTE GOUT ATTACKS
PROPHYLACTIC ANTIINFLAMMATORY THERAPY FOR PATIENTS WITH GOUT
URATE-LOWERING THERAPY
SUMMARY
REFERENCES
Index

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