Evolving Therapies in Esophageal Carcinoma, An Issue of Thoracic Surgery Clinics

Name: Evolving Therapies in Esophageal Carcinoma, An Issue of Thoracic Surgery Clinics
Brand: Elsevier
Price: 62.99 EUR
Availability: OnlineOnly

Wayne Hofstetter(Autor*in)

Elsevier (Verlag)

Erschienen am 14. November 2013

213 Seiten

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978-0-323-24238-7 (ISBN)

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Inhalt

Cover image
Title page
Table of Contents
Contributors
Consulting Editor
Editor
Authors
Forthcoming Issues
Forthcoming Issues
Recent Issues
Preface: Evolving Therapies in Esophageal Carcinoma
Radiographic and Endosonographic Staging in Esophageal Cancer
Key points
Introduction
Role of staging
Radiographic diagnosis and staging
Restaging with PET
Endoscopic ultrasound
EUS/FNA
Endoscopic mucosal resection
Thoracoscopy and laparoscopy
Other radiographic tests
Summary
Esophageal Cancer Staging
Key points
The past: TNM
The present: 7th edition
Beyond anatomic staging
Summary
Personalizing Therapy for Esophageal Cancer Patients
Key points
Introduction
Patient selection and clinical staging
HGD and T1a esophageal cancer
T1b esophageal cancer
Locally advanced esophageal cancer
Unresectable esophageal cancer
Summary
Endoscopic Management of Barrett's Esophagus with High-Grade Dysplasia and Early-Stage Esophageal Adenocarcinoma
Key points
Introduction
Endoscopic surveillance of BE
Diagnosis and staging
Endoscopic treatment
Radiofrequency ablation
Cryotherapy
Endoscopic resection
Multimodality therapy: combining endoscopic resection with mucosal ablation
Summary
Surgery for Esophageal Cancer
Key points
Extent of lymphadenectomy
Resection margin
Induction Therapy for Esophageal Cancer
Key points
Introduction
Rationale for induction therapy
Preoperative radiotherapy followed by surgery
Induction chemotherapy followed by surgery
Induction chemoradiation followed by surgery
Induction chemotherapy followed by surgery versus induction chemoradiation followed by surgery
Future directions: incorporating targeted therapies
Summary
Neoadjuvant Chemotherapy or Chemoradiotherapy for Locally Advanced Esophageal Cancer
Key points
Overview
Issues to be considered
Specific issues
Locoregional control
Future RCTs
Summary
Adjuvant (Postoperative) Therapy for Esophageal Cancer
Key points
Introduction
Adjuvant chemoradiation
Adjuvant chemotherapy
Perioperative chemotherapy
Preoperative chemoradiation
Preoperative versus definitive chemoradiation for SCC
Targeted therapies
Summary
Update on Clinical Impact, Documentation, and Management of Complications Associated with Esophagectomy
Key points
Effect of complications on outcomes of esophageal resection for cancer
Current systems for documenting morbidity associated with esophagectomy
New systems for stratifying severity and resource utilization of complications
Influence of operative technique on complications
Major complications associated with esophageal resection
Anastomotic and conduit complications
Other complications associated with esophageal resection
Methods of affecting the incidence of complications associated with esophagectomy
Complications associated with esophagectomy in elderly patients
Chemoradiation for Esophageal Cancer
Key points
Introduction
Summary
Salvage Esophagectomy in the Management of Recurrent or Persistent Esophageal Carcinoma
Key points
Introduction
Relevant anatomy
Clinical presentation
Diagnosis and clinical restaging
Patient selection
Clinical outcomes
Summary
Supplementary data
Quality of Life in Patients with Esophageal Cancer
Key points
Introduction
HRQOL instruments
HRQOL after curative-intent treatment for esophageal cancer
Summary
Index

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