Drug Discovery and Development E-Book
Beschreibung
With unprecedented interest in the power that the modern therapeutic armamentarium has to combat disease, the new edition of Drug Discovery and Development is an essential resource for anyone interested in understanding how drugs and other therapeutic interventions are discovered and developed, through to clinical research, registration, and market access.
The text has been thoroughly updated, with new information on biopharmaceuticals and vaccines as well as clinical development and target identification. Drug discovery and development continues to evolve rapidly and this new edition reflects important changes in the landscape.
Edited by industry experts Raymond Hill and Duncan Richards, this market-leading text is suitable for undergraduates and graduates undertaking degrees in pharmacy, pharmacology, toxicology, and clinical development through to those embarking on a career in the pharmaceutical industry.
- Key stages of drug discovery and development
- Chapters outline the contribution of individual disciplines to the overall process
- Supplemented by specific chapters on different modalities
- Includes coverage of Oligonucleotide therapies; cell and gene therapy
- Now comes with online access on StudentConsult
Weitere Details
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Andere Ausgaben
Inhalt
Section 1 Introduction and Background
1. Development of the pharmaceutical industry
2. Nature of disease and purpose of therapy
3. Therapeutic modalities
Section 2 Drug Discovery
4. Drug target identification
5. Selecting the modality and planning the project
6. High throughput screening
7. Medicinal Chemistry
8. Biopharmaceuticals and related molecules
9. Emerging modalities: nucleotide based therapy, cell based therapy, gene therapy / Novel and Advanced Process
10. Metabolism and Pharmacokinetical strategies.
11. Role of pharmacology to include pharmacology of newer modalities
12. In vitro in vivo translation
13. Vaccines
Section 3 Drug Development
14. Drug development introduction
15. Drug safety
16. Pharmaceutical development
17. Clinical development
18. Clinical imaging
19. Intellectual property
20. Regulatory affairs
21. Marketing and Patient access to medicines
Section 4 Facts and Figures
22. Facts and Figures; and the Future
