
Oxford Handbook of Epidemiology for Clinicians
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Inhalt
- Cover
- Contents
- Symbols and abbreviations
- Glossary of terms
- A
- B
- C
- D
- E
- F
- H
- I
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- V
- Statistical formulae
- Section 1 Epidemiology in the clinic
- Introduction
- 1 The diagnostic process
- Introduction: epidemiology in the clinic
- Measures of disease frequency
- Distribution of disease
- Is there anything wrong?
- Risk factors
- Identifying risk factors
- Validity of diagnostic tests
- Clinical uses of predictive value
- Pre-test probability
- Likelihood ratios and post-test probabilities
- So what has my patient got? The Bayesian clinician
- 2 Management decisions
- Decisions, decisions . . . the principles of clinical management
- What is prognosis? Looking into the crystal ball
- Prognosis: mortality
- Prognosis: morbidity
- Evidence-based management
- Clinical guidelines
- How effective is the treatment?
- Interpreting reports of clinical trials
- How appropriate is the treatment?
- Patient-centred decision-making
- 3 Risk communication and promoting health
- Health promotion in clinical practice
- Could it have been prevented?
- Communicating risk
- Health promotion in the clinic
- Smoking and alcohol advice
- Exercise, weight, and dietary advice
- Sexual health
- Outbreak investigation
- Breaking the chain of infection
- Section 2 Evidence-based practice
- Introduction
- 4 Finding and summarizing evidence
- Finding and evaluating existing evidence
- Electronic resources
- Critical appraisal
- Appraisal checklists
- CONSORT statement
- Systematic review
- Meta-analysis
- Analysis and interpretation of a meta-analysis
- 5 Preventive medicine and screening
- Prevention strategies
- Levels of prevention
- Preventing communicable disease
- Preventing non-communicable disease: example of cardiovascular disease
- Basic infectious disease epidemiology
- Vaccination
- Screening overview
- Screening programmes
- Evaluating screening programmes
- Major UK screening programmes
- 6 Evaluating clinical practice
- Introduction
- Clinical governance and ethics
- Carrying out an audit: getting started
- Choosing the standards
- Writing your protocol
- Choosing the sample
- Data collection
- Data collection: examples
- Analysing data
- Interpreting findings
- Changing practice
- Completing the process
- Section 3 Epidemiological methods
- Introduction
- 7 Types of study
- Types of evidence and study designs
- Basic concepts in epidemiological research
- Interpreting associations
- Confounding
- Association or causation?
- The nature of causality
- Time trend and geographical (ecological) studies
- Ecological studies: examples
- Surveys and cross-sectional studies
- Cross-sectional studies: examples
- Case-control studies
- Case-control studies: examples
- Cohort studies
- Cohort studies: examples
- Intervention studies and clinical trials
- Clinical trials: examples
- Clinical trial phases
- Choosing the right type of study
- 8 Sources of data
- Introduction: good quality data
- Routine data
- Clinical uses of routine data
- Death certification
- Referral to the coroner
- Infectious disease notification
- Cancer registration
- 9 Statistical concepts
- Introduction
- Data and variables
- Summarizing sample data
- Measures of central location
- Measures of dispersion
- Sampling variability
- Probability distributions
- Confidence intervals
- Hypothesis tests
- Statistical or clinical significance
- Sample size and power calculations
- When to consult a statistician
- 10 Statistical techniques in clinical medicine
- Independent t-test
- Paired t-tests
- Confidence intervals for a proportion
- Normal test for difference in proportions
- Chi-squared test for association
- Parametric and non-parametric tests
- Mann-Whitney U test
- Wilcoxon's signed-rank test
- Linear regression
- Correlation coefficients
- T-tests for regression coefficients
- Multiple regression
- Analysis of variance
- Logistic regression
- Measuring survival
- Kaplan-Meier product limit estimator
- Log-rank test
- Cox proportional hazards model
- Receiver operating characteristic curves
- Section 4 Epidemiology of common diseases
- Introduction
- 11 Global burden of disease
- Terminology
- Global burden of non-communicable disease
- Burden of non-communicable disease in the UK
- Global burden of communicable disease
- Burden of communicable disease in the UK
- 12 Epidemiology of diseases
- Arthritis
- Asthma
- Bladder cancer
- Brain and CNS cancer
- Breast cancer
- Cardiovascular disease
- Cerebrovascular disease
- Cervix cancer
- Chronic obstructive pulmonary disease
- Cirrhosis of the liver
- Colorectal cancer
- Coronary heart disease
- Dementia
- Depression
- Diabetes
- Emerging infectious disease
- Gastroenteritis
- Healthcare associated infections
- High blood pressure and hypertension
- HIV/AIDS
- Influenza
- Kidney cancer
- Leukaemia
- Liver cancer
- Lung cancer
- Malaria
- Malignant melanoma
- Measles
- Meningococcal disease
- Neglected tropical diseases
- Non-Hodgkin lymphoma
- Oesophageal cancer
- Pancreatic cancer
- Peptic ulcer disease
- Prostate cancer
- Road traffic accidents
- Self-inflicted injuries
- Sexually transmitted infections
- Stomach cancer
- Tuberculosis
- Viral hepatitis
- Index
- A
- B
- C
- D
- E
- F
- H
- H
- I
- J
- K
- L
- M
- N
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- P
- Q
- R
- S
- T
- U
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- W
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