Human papillomavirus (HPV) is a major cause of cervical cancer. Human Papillomavirus Infections in Dermatovenereology pulls together the diverse disciplines of clinical, molecular biological, socio epidemiological, and immunological research to bridge the gap between the clinical aspects and basic biology of HPV. This volume provides a much-needed overview of the scientific and clinical data of HPV and HPV-associated diseases, exploring opinions on current therapies and diagnostic methods. It critically reviews the most frequently used molecular biologic methods, evaluating their potential in HPV detection. Specialists in dermatology, genitourinary medicine, gynecology, urology, as well as pathologists, microbiologists, epidemiologists, and virologists will appreciate this timely examination of the ubiquitous pathogen, HPV.
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978-1-040-28216-8 (9781040282168)
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Schweitzer Klassifikation
Historical Overview: Historical Overview. Virology and Basic Biology: Molecular Biology of HPV and Mechanisms of Keratinocyte Transformation. The Nonhuman (Animal) Papillomaviruses: Host Range, Epitope Conservation, and Molecular Diversity. Classification of the Human Papillomaviruses Based on Their Molecular Evolutionary Relationship. Epidemiology and Modes of Transmission: Epidemiology and Modes of Transmission. Natural History and Association to Cancer: HPV Types in Human Disease. Warts and HPV-Related Squamous Cell Tumors of the Skin. Epidermodysplasia Verruciformis as a Model for HPV-Related Oncogenesis. Condyloma Acuminatum and Other HPV-Related Squamous Cell Tumors of the Genitoanal Area. HPV-Related Squamous Cell Tumors of the Airways and Esophagus: Epidemiology and Malignant Potential. Immunological Modulation: The Regulatory Influence of Immunological Host Responses. HPV-Related Disease in Immunosuppressed Individuals. Clinical Presentation and Evaluation: Warts and HPV-Related Squamous Cell Tumors of the Skin: Gross Morphology and Histology. Warts and HPV-Related Squamous Cell Tumors of the Genitoanal Area in Adults. Warts and HPV-Related Squamous Cell Tumors of the Genitoanal Area in Children. HPV-Related Squamous Cell Tumors of the Airways and Esophagus: Clinical Presentation. Recurrent Respiratory Papillomatosis. Cytology and Histology. Detection of Genital Human Papillomavirus Infection and Possible Clinical Implications. The Current Role of HPV Serology. Therapy: Skin Warts. Genitoanal Lesions. Prospects for Vaccination. Index.
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