Fungal immunology, an expanding field of research, studies the interaction between fungi and the immune system. Modulated immunity as well as evasive mechanisms played by fungi all contribute to the chronicity and reoccurrence of fungal infections. Hypersensitivity to various fungal elements plays a major role in the pathogenesis of many diseases.
This book will serve as a comprehensive review of all known immune mechanisms for common medically important fungal pathogens. Its novelty lies in the organization: Rather than chapters devoted to specific fungi, chapters are organized by organ system. All other texts in the field, which are now quite old, are arranged according to specific fungi. Organization by body system rather than fungi is important because one particular fungus can have a different effect on defense mechanisms in different parts of the body.
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ISBN-13
978-0-387-25445-6 (9780387254456)
DOI
Schweitzer Klassifikation
Nasal Cavity.- Fungal Sinusitis.- Oral Cavity.- Innate Defense Mechanisms in Oral Candidiasis.- Humoral Factors in the Protection of the Oral Cavity against Candidiasis.- Oral Candidiasis: Clinical Manifestations and Cellular Adaptive Host Responses.- Lungs.- The Innate and Adaptive Immune Response to Pulmonary Histoplasma capsulatum Infection.- Lung Immunity to Blastomyces dermatitidis Infection.- Innate Immunity in the Lungs to Cryptococcal Infection.- Pulmonary Cell-Mediated Immunity (CMI) to Cryptococcus neoformans.- Antibody-Mediated Immunity to Fungi in the Lungs.- Pulmonary Paracoccidioidomycosis.- The Innate and Acquired Pulmonary Immune Response to Aspergillus fumigatus.- Fungal Hypersensitivity in the Lungs.- Immunology of Pulmonary Pneumocystis Infection: Cell-Mediated Immunity.- Antibody-Mediated Immunity to Pneumocystis in the Lungs.- Gastrointestinal Tract.- Innate and Adaptive Immunity against Candida spp. Infections in the Gastrointestinal Tract.- Vaginal Tract.- Innate and Adaptive Cell-Mediated Immunity against Vaginal Candidiasis.- The Role of Humoral Immunity against Vaginal Candida Infection.- Blood.- Role of Complement in Fungal Infections.- Innate and Adaptive Immunity to Systemic Candida albicans Infection.- Interactions of Fungi with Endothelial Cells.- Skin.- Immunology of Cutaneous Candidiasis.- Immune Surveillance against Dermatophyte Infection.- Immune Surveillance against Sporothrix schenckii Infection.- Central Nervous System.- Innate and Acquired Immunity in Cryptococcus neoformans Infections of the Central Nervous System.
