Direct Oral Anticoagulants in Clinical Practice, An Issue of Hematology/Oncology Clinics of North America
Direct Oral Anticoagulants in Clinical Practice, an Issue of Hematology/Oncology Clinics of North America
1. Auflage
Erschienen am 16. September 2016
100 Seiten
978-0-323-46315-7 (ISBN)
Beschreibung
This issue of Hematology/Oncology Clinics is devoted to New Anticoagulant and Antithrombotic Agents and will include articles such as: Development and Pharmacology; Post Orthopedic Joint Replacement Surgery VTE Prophylaxis; Use for Afib; Treatment of Acute VTE; Extended Treatment of VTW; Bleeding Risks: Use in Special Poplulations; Monitoring Anticoagulant Effect, and many more articles surrounding this important title.
Weitere Details
Weitere Ausgaben
Andere Ausgaben
Jean Marie Connors
Direct Oral Anticoagulants in Clinical Practice: An Issue of Hematology/Oncology Clinics of North America: Volume 30-5
Volume 30-5
Buch
11/2016
Elsevier
110,50 €
Versand in 15-20 Tagen
Inhalt
- Intro
- Title page
- Table of Contents
- Copyright
- Contributors
- Forthcoming Issues
- Preface
- The History of Antithrombotic Therapy: The Discovery of Heparin, the Vitamin K Antagonists, and the Utility of Aspirin
- Key points
- The discovery of heparin: who did what when?
- The discovery of the vitamin K antagonists: spoiled clover, bloody cattle, and rat genocide
- The utility of aspirin as an antithrombotic agent: a new use for an ancient drug
- Summary
- Direct Oral Anticoagulants: Monitoring Anticoagulant Effect
- Key points
- Introduction
- Diagnostic options
- Direct oral anticoagulants levels and clinical outcomes
- Limitations
- Summary
- Postorthopedic Surgery Joint Replacement Surgery Venous Thromboembolism Prophylaxis
- Key points
- Introduction
- History of factor Xa inhibitors
- Discussion
- Non-Vitamin K Antagonist Oral Anticoagulants in Atrial Fibrillation
- Key points
- Introduction
- Non-vitamin K antagonist oral anticoagulants
- Post acceptance update
- Use of the Direct Oral Anticoagulants for the Treatment of Venous Thromboembolism
- Key points
- Introduction
- Pharmacologic properties of the direct oral anticoagulants
- Treatment of acute venous thromboembolism
- Extended treatment of venous thromboembolism
- Treatment of special populations
- Use of the direct oral anticoagulants in routine clinical practice
- Summary of evidence
- Use of Direct Oral Anticoagulants in Special Populations
- Key points
- Introduction
- Patients at extremes of body weight
- Elderly patients over 75 years of age
- Patients with moderate or severe renal impairment
- Patients with cancer
- Patients known to have thrombophilia other than cancer
- Summary
- Perioperative Management of the Direct Oral Anticoagulants: A Case-Based Review
- Key points
- Introduction
- Case 1: minimal-bleed-risk procedure
- Case 2: high thrombotic risk
- Case 3: low-bleed-risk procedure
- Case 4: urgent surgery
- Summary
- Reversal Agents for the Direct Oral Anticoagulants
- Key points
- Introduction
- When will reversal agents be needed?
- Attributes of a useful reversal agent
- Do the vitamin K antagonists have a reversal agent?
- Current state of reversal of direct oral anticoagulants before the advent of specific agents
- Specific reversal agents for the direct oral anticoagulants
- The future of direct oral anticoagulants reversal agents
- The Intrinsic Pathway of Coagulation as a Target for Antithrombotic Therapy
- Key points
- Introduction
- The intrinsic pathway in models of blood coagulation
- The intrinsic pathway and thrombosis
- Trials of agents targeting components of the intrinsic pathway
- Summary
- Regulatory Impact on Thrombosis Treatment, Prevention, and Anticoagulant Use
- Key points
- Introduction
- Overview of organization interactions and performance measures
- Targeted performance standards
- Surgical care improvement projects
- Point scoring systems
- Electronic health record meaningful use
- The National Action Plan for Adverse Drug Event Prevention
- Postmarketing surveillance
- Product contamination and pharmaceutical supply chain
- Litigation
- Summary
- Index
