Calcium and Phosphate Transport Across Biomembranes is a collection of papers presented at the 1981 Calcium and Phosphate Transport Across Biomembranes international workshop held in Vienna, Austria. Contributors from a wide range of disciplines explore the intracellular role of calcium and phosphate and their transport into and out of the body through the intestine and the kidney. In particular, they describe calcium movement in the cell and across the plasma membrane, along with phosphate transport into the cell, particularly, at the brush border. Organized into 10 sections encompassing 53 chapters, this collection begins with an overview of the mechanisms underlying the net movements of calcium in the cell and plasma membrane. The discussion then shifts to the crystal structure of calmodulin, the phosphate transport in the mitochondria, the mechanisms for calcium extrusion, the calcium uptake by brush border membranes, and the possible role of the mitochondria in intracellular calcium regulation. The book also introduces the discussion on mitochondrial calcium transport protein, polypeptide and amine hormone regulation of calcium fluxes, mechanism of secretion by cultured pituitary cells, and regulation of the tubular transport of phosphate. A chapter that assesses the effects of vitamin D and insulin on phosphate transport in the differentiating chick small intestine concludes the book. This collection of papers will be of interest to scientists, neurochemists, physiologists, pharmacologists, biochemists, gastroenterologists, nutritionists, and pathophysiologists.
Sprache
Verlagsort
Verlagsgruppe
Elsevier Science & Techn.
ISBN-13
978-0-323-15591-5 (9780323155915)
Schweitzer Klassifikation
ContributorsPrefaceAcknowledgmentsI. Calcium Transport-Generalized Cell and Plasma Membrane Mechanisms Underlying the Net Movements of Calcium in Nerve Ca2+ Pumping Systems in the Plasma Membrane Calcium Transport Mechanisms in Cardiac Sarcolemmal Vesicles The Ca2+ -ATPase of Heart Sarcolemma: Purification and Control MechanismsII. Calmodulin S-100: A Calcium-Trigger Protein Toward a Determination of the Crystal Structure of Calmodulin Two Distinct Calmodulins Characterized in Eggs of Arbacia punctulata Azido- 125I-Calmodulin, a Photoaffinity Probe for the Study of Calmodulin as a Regulator of Plasma Membrane Ca2+ TransportIII. Calcium Transport-Endoplasmic and Sarcoplasmic Reticulum The Control of Cytoplasmic Free Calcium in Presynaptic Nerve Terminals Calcium Transport across the Sarcoplasmic Reticulum Phosphorylation of Sarcoplasmic Reticulum ATPase of Skeletal Muscle from OrthophosphateIV. Mitochondrial Calcium and Phosphate Transport Ca2+ Transport by Mitochondria: A Survey Regulation of Free Ca2+ by Cardiac Mitochondria and Skinned Myocytes Calcium Transport across the Plasma Membrane and Inner Mitochondrial Membrane in Synaptosomes Mitochondria Do Not Accumulate Significant Ca Concentrations in Normal Cells Calciphorin: A Mitochondrial Calcium Ionophore Inorganic Phosphate Transport across the Inner Mitochondrial Membrane Toward an Analysis of the Catalytic Mechanism with the Purified Transport ProteinV. Calcium and Phosphate Transport -Epithelial Cell Membranes Calcium and Phosphate Transport across Renal Plasma Membranes: Concepts, Problems, and Future Developments Calcium and Inorganic Phosphate Fluxes across Membranes Isolated from Proximal Tubular and Small Intestinal Epithelium The Effect of pH on the Transport of Phosphate by Renal Brush Border Membrane Vesicles Identification of a Phosphate-Binding Proteolipid in Kidney Brush BorderVI. Intestinal Calcium Transport Introduction: Calcium and Phosphate Transport by the Intestinal Cell Intestinal Calcium Absorption Regulation of Diurnal Periodicity of Active Calcium Transport in Rat Small Intestine Calcium Absorption in Suckling and Postweaning Rats Small Intestinal Site, Calcium Transport Kinetics, and Calcium Homeostasis in the Hamster Imcal: Vitamin D-Dependent Membrane Component of the Intestinal Calcium Transport Mechanism High Affinity Ca-ATPase in Basolateral Plasma Membranes of Rat Duodenum and Kidney Cortex Calmodulin-Sensitive, ATP-Dependent Calcium Transport by Plasma Membrane of Small Intestinal Epithelium Ileal Calcium and Phosphate Absorption in Chronic Renal FailureVII. Intestinal Phosphate Transport Phosphate Transport in the Intestine: Cellular Pathways and Hormonal Regulation Intestinal Phosphate Transport and Alkaline Phosphatase Effect of E H D P Treatment on the Na-Dependent Phosphate Influx in Rabbit Small Intestine and NerveVIII. Renal Calcium Transport Calcium Transport by Kidney Cells Calcium Transport across the Cortical Thick Ascending Limb of Henle's Loop Sodium-Calcium Interaction in Renal Tubular Epithelium Hyperglycemic CalciuriaIX. Renal Phosphate Transport Regulation of the Tubular Transport of Phosphate: Relationship between the Whole Kidney, the Proximal Tubule, and Brush Border Membrane Vesicles Effect of 1,25(OH)2D3 on Renal and Intestinal Transport of Phosphate Anion in Hyp Mouse Effects of Disturbances of Potassium Balance on Renal Handling of Titratable Acid and Phosphate in the Rat: A Micropuncture Study Maleate Tubular Dysfunction: Effects of Acetoacetate and 1,25(OH)2D3X.