Countercurrent Chromatography

Name: Countercurrent Chromatography
Brand: Elsevier
Price: 265.0 EUR
Availability: OnlineOnly

A. Berthod(Autor*in)

Elsevier (Verlag)

Erschienen am 10. Oktober 2002

422 Seiten

E-Book

ePUB mit Wasserzeichen-DRM

Systemvoraussetzungen

978-0-08-092966-8 (ISBN)

265,00 €inkl. 7% MwSt.

Systemvoraussetzungen

für ePUB mit Wasserzeichen-DRM

E-Book Einzellizenz

Als Download verfügbar

Beschreibung

Weitere Details

Weitere Ausgaben

Inhalt

Cover image
Title page
Table of Contents
Comprehensive Analytical Chemistry Advisory Board
Wilson & Wilson's Comprehensive Analytical Chemistry
Copyright page
Contributors to Volume XXXVIII
Wilson and Wilson's Comprehensive Analytical Chemistry
Foreword
Series Editor's Preface
Preface
Chapter 1: Fundamentals of countercurrent chromatography
1.1 Introduction
1.2 A Liquid Stationary Phase
1.3 Chromatographic Theory
1.4 CCC and HPLC
1.5 Hydrodynamic and Hydrostatic CCC Columns
1.6 Conclusion
Chapter 2: Operating a countercurrent chromatography machine
2.1 Introduction
2.2 Liquid System Preparation
2.3 Apparatus Preparation
2.4 Effect of Machine Specifications on Separations
2.5 Working With a Wide Polarity Range
2.6 Two Practical Examples
2.7 Conclusion
Chapter 3: Solvent systems
3.1 Introduction
3.2 Generalities on Biphasic Solvent Systems
3.3 Strategies for Solvent-System Selection
3.4 From an Empty Box to a Fit Column
3.5 Conclusion
Chapter 4: Centrifugal partition chromatography: the story of a company
4.1 Introduction
4.2 The Story of CPC
4.3 Newcomers and New Approaches
4.4 Future Trends
Chapter 5: Centrifugal partition chromatography: an engineering approach
5.1 Introduction
5.2 Assumptions and First Visualizations
5.3 Chromatography Curves Model
5.4 Flow Patterns, Residence Time Distribution and Mass Transfer
5.5 Conclusion
Chapter 6: Liquid stationary phase retention and resolution in hydrodynamic CCC
6.1 Introduction
6.2 Head/Tail Rule
6.3 Measuring Dead Volume (Vd) and Retention of the Stationary Phase (Sf) in the Coil Planet Centrifuge
6.4 Predicting Peak Elution
6.5 Modelling CCC Using an Eluting CCD Model
6.6 Practical Application of the Model
6.7 Conclusions
Chapter 7: Special uses of a support-free liquid stationary phase
7.1 Introduction
7.2 Displacement Chromatography
7.3 pH-Zone Refining
7.4 Liquid-Liquid Partition Coefficient Determination
7.5 Other Uses of the Liquid Nature of the Stationary Phase
7.6 Conclusion
Chapter 8: Separation and purification of natural products (medicinal herbs) by high speed countercurrent chromatography
8.1 Introduction
8.2 Apparatus for High-Speed CCC
8.3 Applications of Semi-Preparative HSCCC
8.4 Applications of Analytical HSCCC
8.5 Application of Two-Dimensional HSCCC Systems
8.6 Applications of the Ph-Zone-Refining CCC System
8.7 Applications for a Cross-Axis CCC Machine [17-20]
8.8 Conclusion
Chapter 9: Separation of inorganic compounds: theory, methodology and applications
9.1 Introduction
9.2 Theory
9.3 Methodology
9.4 Applications
9.5 Summary
Chapter 10: The use of CCC in the pharmaceutical industry
10.1 Introduction
10.2 The Use of CCC for Natural Product Crude Extract Fractionation
10.3 The Use of CCC for Bioassay-Guided Isolation of Natural Products
10.4 Industrial Scaleup of CCC
10.5 Future Directions
Acknowledgements
Chapter 11: Enantioseparations in countercurrent chromatography and centrifugal partition chromatography
11.1 Introduction
11.2 Chiral Separations
11.3 Chiral CCC: The Pioneers
11.4 N-Dodecanoyl-L-Proline-3,5-Dimethylanilide
11.5 Sulfated ß-Cyclodextrin
11.6 Bovine Serum Albumin (BSA)
11.7 Vancomycin
11.8 Cinchona Alkaloid Derivatives
11.9 Chiral CCC Reactor
11.10 Conclusion
Chapter 12: Supercritical fluids as mobile phases in CCC
12.1 Introduction
12.2 Experimental Apparatus and Procedures
12.3 Separation of Some Small Organic Compounds
12.4 Separation of Steroids
12.5 Supercritical Fluid Extraction Using a CCC Apparatus
12.6 Conclusions and Perspectives
Appendix: Commercially available countercurrent chromatographs
A.1 Twentieth Century CCC Technology
A.2 Twenty-First Century CCC Machines
Glossary
Symbols Used
Abbreviations
Index

Systemvoraussetzungen

Als PDF speichern Als Link merken