
Neuroanatomy and Neuroscience at a Glance
Beschreibung
Neuroanatomy and Neuroscience at a Glance is a highly illustrated, quick reference guide to the anatomy, biochemistry, physiology and pharmacology of the human nervous system. Each chapter features a summary of the anatomical structure and function of a specific component of the central nervous system, a section on applied neurobiology outlining how to approach a patient with neurological or psychiatric problems aligned to the chapter topic, standard diagnostic procedures for most common scenarios, as well as an overview of treatment and management options.
This fully updated and expanded new edition includes:
* Dozens of full-page, colour illustrations and neurological scans
* Expanded coverage of techniques to study the nervous system
* More practical information on the neurological exam
* New content on neuropharmacology and drug therapies
* Bullet points and bold terms throughout assist with revision and review of the topic
Neuroanatomy and Neuroscience at a Glance is the ideal companion for students embarking on a neuroanatomy or neuroscience course, and is an excellent reference tool for those in clinical training.
An updated companion website with new clinical cases, multiple choice self-assessment questions, revision slides, and downloadable illustrations and flashcards is available at www.ataglanceseries.com/neuroscience
Weitere Details
Weitere Ausgaben
Personen
Roger A. Barker BA, MBBS, MRCP, PhD, FMedSci, John van Geest Centre for Brain Repair and Department of Neurology, Department of Clinical Neuroscience, University of Cambridge, Cambridge, UK.
Francesca Cicchetti PhD, Centre de Recherche du CHU de Québec (CHUQ), Université Laval, Québec, Canada.
Emma S.J. Robinson PhD, FBPhS, School of Physiology, Pharmacology & Neuroscience, University of Bristol, Bristol, UK.
Inhalt
Acknowledgements
List of abbreviations
Companion website
Anatomical and functional organization
1 Development of the nervous system
2 Organization of the nervous system
3 Autonomic nervous system
4 Enteric nervous system
5 Meninges and cerebrospinal fluid
6 Blood supply to the central nervous system
7 Cranial nerves
8 Anatomy of the brainstem
9 Organization of the spinal cord
10 Organization of the cerebral cortex and thalamus
11 Hypothalamus
Cells and neurophysiology
12 Cells of the nervous system I: neurones
13 Cells of the nervous system II: neuroglial cells
14 Ion channels
15 Resting membrane and action potential
16 Neuromuscular junction and synapses
17 Nerve conduction and synaptic integration
18 Neurotransmitters, receptors and their pathways
19 Main CNS neurotransmitters and their function
20 Skeletal muscle structure
21 Skeletal muscle contraction
Sensory systems
22 Sensory systems: an overview
23 Sensory transduction
24 Visual system I: the eye and retina
25 Visual system II: the visual pathways and subcortical visual areas
26 Visual system III: visual cortical areas
27 Auditory system I: the ear and cochlea
28 Auditory system II: auditory pathways and language
29 Vestibular system
30 Olfaction and taste
31 Somatosensory system
32 Pain systems I: nociceptors and nociceptive pathways
33 Pain systems II: pharmacology and management
34 Association cortices: the posterior parietal and prefrontal cortex
Motor systems
35 Organization of the motor system
36 Muscle spindle and lower motor neurone
37 Spinal cord motor organization and locomotion
38 Cortical motor areas
39 Primary motor cortex
40 Basal ganglia: anatomy and physiology
41 Basal ganglia: diseases and their treatments
42 Cerebellum
Cognition and neural plasticity
43 Reticular formation and sleep
44 Limbic system and long-term potentiation
45 Memory
46 Emotion, motivation and drug addiction
47 Neural plasticity and neurotrophic factors I: the peripheral nervous system
48 Neural plasticity and neurotrophic factors II: the central nervous system
49 Techniques for studying the nervous system
Applied neurobiology: the principles of neurology and psychiatry
50 Approach to the patient with neurological problems
51 Examination of the nervous system
52 Investigation of the nervous system
53 Imaging of the central nervous system
54 Clinical disorders of the sensory systems
55 Clinical disorders of the motor systems
56 Eye movements
57 Neurochemical disorders I: affective disorders
58 Neurochemical disorders II: schizophrenia
59 Neurochemical disorders III: anxiety
60 Neurodegenerative disorders
61 Neurophysiological disorders: epilepsy
62 Neuroimmunological disorders
63 Neurogenetic disorders
64 Cerebrovascular disease
65 Neuroradiological anatomy
History of neuroscientific discoveries
66 Historical neuroscience discoveries
Self-assessment case studies
Case studies and questions
Answers
Index
List of abbreviations
- ACA
- anterior cerebral artery
- ACE-r
- Addenbrooke's Cognitive Examination, revized
- ACh
- acetylcholine
- AChE
- acetylcholinesterase
- AChR
- acetylcholine receptor
- ACTH
- adenocorticotrophic hormone
- ADH
- antidiuretic hormone (vasopressin)
- ADHD
- attention deficit hyperactivity disorder
- ALS
- amyotrophic lateral sclerosis
- ANS
- autonomic nervous system
- APP
- amyloid precursor protein
- ATP
- adenosine triphosphate
- AVM
- arteriovenous malformation
- BBB
- blood-brain barrier
- BDNF
- brain derived neurotrophic factor
- BM
- basilar membrane
- BMP
- bone morphogenic protein
- BPPV
- benign paroxysmal positional vertigo
- BSAEP
- brainstem auditory-evoked potential
- CAA
- cerebral amyloid angiopathy
- CADASIL
- cerebral autosomal-dominant arteriopathy with subcortical infarcts and leucoencephalopathy
- cAMP
- cyclic adenosine monophosphate
- CBM
- cerebellum
- CCK
- cholecystokinin
- cf
- climbing fibre
- cGMP
- cyclic guanosine monophosphate
- CMCT
- central motor conduction time
- CMUA
- continuous motor unit activity
- CNF
- cuneiform nucleus
- CNS
- central nervous system
- CNTF
- ciliary neurotrophic factor
- COMT
- catecholamine-O-methyltransferase
- CoST
- corticospinal tract
- COX
- cyclo-oxygenase
- CPAP
- continuous positive airway pressure
- CPG
- central pattern generator
- CPK
- creatine phosphokinase
- CRH
- corticotrophin-releasing hormone
- CRPS
- complex regional pain syndrome
- CSF
- cerebrospinal fluid
- CT
- computed tomography
- CVA
- cerebrovascular accident
- DA
- dopamine
- DAG
- diacylglycerol
- DAT
- dementia of the Alzheimer type
- DAT
- dopamine transporter (scan)
- dB
- decibel
- DC
- dorsal column
- DCN
- dorsal cochlear nucleus
- DoCN
- dorsal column nuclei
- DCNN
- deep cerebellar nuclei neurone
- DMD
- Duchenne's muscular dystrophy
- DNA
- deoxyribonucleic acid
- DREADD
- Designer Receptors Exclusively Activated by Designer Drugs
- DRG
- dorsal root ganglion
- DSCT
- dorsal spinocerebellar tract
- DSIP
- delta sleep-inducing peptide
- DSM-V
- Diagnostic and Statistical Manual of Mental Disorders, 5th edition
- ECG
- electrocardiography/electrocardiogram
- ECT
- electroconvulsive therapy
- EEG
- electroencephalography/electroencephalogram
- EMG
- electromyography/electromyogram
- ENS
- enteric nervous system
- EP
- evoked potential
- epp
- end-plate potential
- EPSP
- excitatory postsynaptic potential
- FDG
- [18F]2-fluoro-2-deoxy-D-glucose
- FEF
- frontal eye field(s)
- fMRI
- functional magnetic resonance imaging
- FTD
- fronto-temporal dementia
- GABA
- ?-aminobutyric acid
- GAD
- glutamic acid decarboxylase
- GDNF
- glial cell line derived neurotrophic factor
- GoC
- Golgi cell
- GPe
- globus pallidus, external segment
- GPi
- globus pallidus, internal segment
- G-protein
- guanosine triphosphate-binding protein
- GrC
- granule cell
- GTO
- Golgi tendon organ
- GWAS
- genome-wide association study
- HIV
- human immunodeficiency virus
- HLA
- histocompatibility locus antigen
- HMM
- heavy meromyosin
- HMSN
- hereditary motor sensory neuropathy
- HPA
- hypothalamic-pituitary-adrenal
- HPLC
- high-performance liquid chromatography
- 5-HT
- 5-hydroxytryptamine (serotonin)
- HTM
- high-threshold mechanoreceptor
- Hz
- hertz
- IC
- inferior colliculus
- ICA
- internal carotid artery
- IHC
- inner hair cell
- ILN
- intralaminar nuclei (of the thalamus)
- IN
- interneurone
- IP3
- inositol triphosphate
- IPAN
- intrinsic primary afferent neurones
- iPS
- induced pluripotent stem cell
- IPSP
- inhibitory postsynaptic potential
- JPS
- joint position sense
- LC
- locus coeruleus
- LEMS
- Lambert-Eaton myasthenic syndrome
- LGMD
- limb girdle muscular dystrophy
- LGN
- lateral geniculate nucleus of the thalamus
- LMM
- light meromyosin
- LMN
- lower motor neurone
- LTD
- long-term depression
- LTP
- long-term potentiation
- MAO
- monoamine oxidase
- MAOA
- monoamine oxidase type A
- MAOB
- monoamine oxidase type B
- MAOI
- monoamine oxidase inhibitor
- MCA
- middle cerebral artery
- mepp
- miniature end-plate potential
- MGN
- medial geniculate nucleus of the thalamus
- MHC
- major histocompatibility complex
- MLF
- medial longitudinal fasciculus
- MMSE
- Mini Mental State Examination
- MN
- motor neurone
- MND
- motor neurone disease
- MRA
- magnetic resonance angiography
- MRC
- Medical Research Council
- MRI
- magnetic resonance imaging
- MRV
- magnetic resonance venography
- MsI
- primary motor cortex
- MUSK
- muscle-specific kinase
- NA
- noradrenaline (norepinephrine)
- nAChR
- nicotinic acetylcholine receptor
- NCS
- nerve conduction studies
- NFT
- neurofibrillary tangle
- NGF
- nerve growth factor
- NMDA
- N-methyl-D-aspartate
- NMDA-R
- N-methyl-D-aspartate glutamate receptor
- NMJ
- neuromuscular junction
- NO
- nitric oxide
- NS
- neostriatum
- NSAID
- non-steroidal anti-inflammatory drug
- NSF
- N-ethylmaleimide sensitive fusion protein
- OB
- olfactory bulb
- OCD
- obsessive compulsive disorder
- OD
- ocular dominance
- OHC
- outer hair cell
- OSA
- obstructive sleep apnoea
- PCA
- posterior cerebral artery
- PCR
- polymerase chain reaction
- PET
- positron emission tomography
- pf
- parallel fibre
- PG
- prostaglandin
- PICA
- posterior inferior cerebellar artery
- PMC
- premotor cortex
- PMN
- polymodal nociceptors
- PMP
- peripheral myelin protein
- PNS
- peripheral nervous system
- PPC
- posterior parietal cortex
- PPN
- pedunculopontine nucleus
- PPRF
- paramedian pontine reticular
formation - PuC
- Purkinje cell
- RA
- rapidly adapting receptor
- REM
- rapid eye movement
- ReST
- reticulospinal tract
- riMLF
- rostral interstitial nucleus of the medial longitudinal fasciculus
- RMS
- rostral migratory stream
- RuST
- rubrospinal tract
- SA
- slowly adapting receptor
- SCA
- spinocerebellar ataxia
- SCT
- spinocerebellar tract
- SHH
- sonic hedgehog
- SLE
- systemic lupus erythematosus
- SMA
- supplementary motor area
- SmI
- primary somatosensory cortex
- SmII
- second somatosensory area
- SNAP
- soluble NSF attachment protein
- SNARE
- SNAP receptor
- SNc
- substantia nigra pars compacta
- SNP
- senile neuritic plaque
- SNr
- substantia nigra pars reticulata
- SNS
- sympathetic nervous system
- SOC
- superior olivary complex
- SP
- substance P
- SPECT
- single photon emission computed tomography
- SR
- sarcoplasmic reticulum
- SSRI
- selective serotonin re-uptake inhibitor
- STN
- subthalamic nucleus
- STT
- spinothalamic tract
- SUDEP
- sudden unexpected death
- SVZ
- subventricular zone
- SWS
- slow-wave sleep
- T
- Tesla
- tDCS
- transcranial direct-current stimulation
- TENS
- transcutaneous nerve stimulation
- TIA
- transient ischaemic attack
- TM
- tectorial membrane
- TMS
- transcranial magnetic stimulation
- TNF
- tumour necrosis factor
- TRH
- thyrotrophin-releasing hormone
- T-tubule
- transverse tubule
- UMN
- upper motor neurone
- UPR
- unfolded protein response
- UPS
- ubiquitin-proteosome system
- V1
- primary visual cortex (Brodmann's area 17)
- VA-VL
- ventroanterior-ventrolateral nuclei of the...
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