This text uses a more brief and qualitative approach to present biochemistry with chemical rigor, focusing on the structures of biomolecules, chemical mechanisms, and evolutionary relationships. It is written to impart a sense of intellectual history of biochemistry, an understanding of the tools and approaches used to solve biochemical puzzles, and a hint of the excitement that accompanies new discoveries. This edition has been thoroughly updated to reflect the most recent advances in biochemistry, particularly in the areas of genomics and structural biology. A new chapter focuses on cytoskeletal and motor proteins, currently one of the most active areas of research in biochemistry.
Rezensionen / Stimmen
"...contains a wealth of high-class pedagogical features...the authors write well and do a fine job in conveying to students the most exciting advances in modern biochemistry." (Times Higher Education Supplement, 24th Feb 2006)
Auflage
Sprache
Verlagsort
Verlagsgruppe
Zielgruppe
Editions-Typ
Illustrationen
Illustrations (some col.)
Maße
Höhe: 28.2 cm
Breite: 22.2 cm
Gewicht
ISBN-13
978-0-471-21495-3 (9780471214953)
Schweitzer Klassifikation
PART I: INTRODUCTION.
Chapter 1. Introduction to the Chemistry of Life.
Chapter 2. Water.
PART II: BIOMOLECULES.
Chapter 3. Nucleotides, Nucleic Acids, and Genetic Information.
Chapter 4. Amino Acids.
Chapter 5. Proteins: Primary Structure.
Chapter 6. Proteins: Three-Dimensional Structure.
Chapter 7. Protein Function Part I: Myoglobin and Hemoglobin.
Chapter 8. Carbohydrates.
Chapter 9. Lipids and Biological Membranes.
Chapter 10. Membrane Transport.
PART III: ENZYMES.
Chapter 11. Enzymatic Catalysis.
Chapter 12. Enzyme Kinetics, Inhibition, and Regulation.
PART IV: METABOLISM.
Chapter 13. Introduction to Metabolism.
Chapter 14. Glucose Catabolism.
Chapter 15. Glycogen Metabolism and Gluconeogenesis.
Chapter 16. Citric Acid Cycle.
Chapter 17. Electron Transport and Oxidative Phosphorylation.
Chapter 18. Photosynthesis.
Chapter 19. Lipid Metabolism.
Chapter 20. Amino Acid Metabolism.
Chapter 21. Mammalian Fuel Metabolism: Integration and Regulation.
Chapter 22. Nucleotide Metabolism.
PART V: GENE EXPRESSION AND REPLICATION.
Chapter 23. Nucleic Acid Structure.
Chapter 24. DNA Replication, Repair, and Recombination.
Chapter 25. Transcription and RNA Processing.
Chapter 26. Translation.
Chapter 27. Regulation of Gene Expression.
Chapter 28. Protein Function Part II: Cytoskeletal and Motor Proteins and Antibodies.
Appendix.
Bioinformatics Exercises.
Answers to Bioinformatics Exercises.
Solutions to Problems.
Glossary.
Guide to Media Resources.
Index.
