Preface to Addiction Review iv
George R. Uhl
Evaluation of reward from pain relief 1
Edita Navratilova, Jennifer Yanhua Xie, Tamara King and Frank Porreca
Associative learning mechanisms underpinning the transition from recreational drug use to addiction 12
Lee Hogarth, Bernard W. Balleine, Laura H. Corbit and Simon Killcross
Lipids and addiction: how sex steroids, prostaglandins, and cannabinoids interact with drugs of abuse 25
Emma Leishman, Kevin J. Kokesh and Heather B. Bradshaw
The genetics of alcohol dependence 39
Marcella Rietschel and Jens Treutlein
Substance use disorders: a theory-driven approach to the integration of genetics and neuroimaging 71
Hollis C. Karoly, Nicole Harlaar and Kent E. Hutchinson
Analytical strategies for large imaging genetic datasets: experiences from the IMAGEN study 92
Charlotte Nymberg, Tianye Jia, Barbara Ruggeri and Gunter Schumann
Addiction and corticotropin-releasing hormone type 1 receptor antagonist medications 107
Carlo Contoreggi, Mary R. Lee and George Chrousos
Deep brain stimulation of the nucleus accumbens for the treatment of addiction 119
Ulf J. Mueller, Juergen Voges, Johann Steiner, Imke Galazky, Hans-Jochen Heinze, Michaela Moeller, Jared Pisapia, Casey Halpern, Arthur Caplan, Bernhard Bogerts and Jens Kuhn
