Volume 1; 1. Introduction and Overview; Kenneth J. Sher, Alvaro A. Verges; Part One: Defining and Characterizing the Nature and Extent of Substance Use Disorders; 2. Historical and Cultural Perspectives on Substance Use and Substance Use Disorders; Christopher S. Martin, Tammy A. Chung, James W. Langenbucher; 3. Illicit Drugs: Patterns of Use, Dependence, and Contribution to Disease Burden in Developed Countries; Louisa Degenhardt, Wayne Hall, Chiara Bucello; 4. The Natural Course of Substance Use and Dependence; Kristina M. Jackson, Carolyn E. Sartor; Part Two: The Neurobiology and Genetics of Substance Use and Dependence ; 5. Mechanisms of Action of Different Drugs of Abuse; Lindsay M. McCracken, Mandy L. McCracken, R. Adron Harris; 6. The Neurobiology of Reward and Stress and Its Relevance for Understanding Drug Seeking and Dependence Symptomatology; George F. Koob; 7. Genetic Epidemiology and Molecular Genetics; Michael C. Stallings, Ian R. Gizer, Kelly C. Young-Wolff; 8. Genetic Animal Models; John C. Crabbe, Tamara J. Phillips; Part Three: Psychological Factors and Substance Involvement; 9. Passion's Slave?: Conscious and Unconscious Cognitive Processes in Alcohol and Drug Abuse; Reinout W. Wiers, Matt Field, Alan W. Stacy; 10. Personality and Substance Use Disorders; Andrew K. Littlefield, Kenneth J. Sher; 11. Motivational Models of Substance Use: A Review of Theory and Research on Motives for Using Alcohol, Marijuana, and Tobacco; M. Lynne Cooper, Emmanuel Kuntsche, Ash Levitt, Lindsay L. Barber, Scott Wolf; 12. Behavioral-Economic and Neuroeconomic Perspectives on Addiction; Warren Bickel, E. Terry Mueller, James MacKillop, Richard Yi; Part Four: Social Factors and Substance Involvement; 13. Familial Factors Influencing Offspring Substance Use and Dependence; Laurie Chassin, Moira Haller, Matthew Lee, Elizabeth Handley, Kaitlin Bountress, Iris Beltran; 14. Substance Use and Race and Ethnicity; Christy McKinney, Raul Caetano; 15. Substance Use and Peers During Adolescence and the Transition to Adulthood; Megan E. Patrick, John E. Schulenberg, Jennifer Maggs, Julie Maslowsky; 16. Substance Use in Committed Relationships; Jaye L. Derrick, Kenneth E. Leonard; 17. Substance Use in Specific Settings; Genevieve Ames, Roland S. Moore; 18. Community-Based Approaches to the Prevention of Substance Use-Related Problems; Paul J. Gruenewald, Andrew J. Treno, Harold D. Holder, Elizabeth A. LaScala; 19. Substance Use and the Media; Cristel Antonia Russell, Dale W. Russell, and Joel Grube; Part Five: Concluding Commentary; 20. Anticipating the Future of Research on Substance Use and Substance Use Disorders; Kenneth J. Sher, Alvaro A. Verges; Index; Volume 2; 1. Introduction and Overview; Kenneth J. Sher, Alvaro A. Verges; Part One: Psychiatric Comorbidity; 2. Polydrug Use: Research Topics and Issues; James Anthony, David A. Barondess, Mirjana Radovanovic, Catalina Lopez-Quintero; 3. ADHD and Substance Use; Karen J. Derefinko, William E. Pelham Jr.; 4. Serious Mental Illness; Kim T. Mueser, Douglas L. Noordsy, Robert E. Drake; 5. Substance Use Disorders and Personality Disorders; Timothy J. Trull, Marika B. Solhan, Whitney C. Brown, Rachel L. Tomko, Lauren Schaefer, Kristin D. McLaughlin, Seungmin Jahng; 6. Comorbidity of Anxiety and Depression with Substance Use Disorders; Sherry Stewart, Valerie V. Grant, Clare J. Mackie, Patricia J. Conrod; 7. An Integrative Common Liabilities Model for the Comorbidity of Substance Use Disorders with Externalizing and Internalizing Disorders; Erin C. Tully, William Iacono; Part Two: Effects of Substance Use on Health and Societal Problems across the Life Span ; 8. Effects of Drug Exposure on Development; Alissa D. Bazinet, Lindsay Squeglia, Edward Riley, Susan F. Tapert; 9. Effects of Alcoholism on Neurological Function and Disease in Adulthood; Marlene Oscar-Berman, Trinity A. Urban, Avram J. Holmes; 10. Substance Involvement and Physical Health; Svetlana Popova, Jurgen Rehm; 11. Substance Use Disorders and Intentional Injury; S. Janet Kuramoto, Holly C. Wilcox; 12. Substance Use and Crime; Helene Raskin White; 13. Substance Use and School and Occupational Performance; Ioana Popovici, Michael T. French; Part Three: Assessing Substance Use and Dependence ; 14. Biological Markers of Substance Use: Focus on the Objective Assessment of Alcohol Exposure; Lawrence D. Snell, Sanjiv V. Bhave, Laszlo Takacs, Boris Tabakoff; 15. Self-report Assessments of Psychoactive Substance Use and Dependence; Frances K. Del Boca, Jack Darkes, Bonnie McRee; 16. Ecocological Momentary Assessment; Saul Shiffman; Part Four: Substance Use Treatment ; 17. Brief Interventions and Motivational Interviewing; Jennifer Hettema, Christopher C. Wagner, Karen S. Ingersoll, Jennifer M. Russo; 18. Cognitive-Behavioral Approaches; Damaris J. Rohsenow, Megan M. Pinkston-Camp; 19. Marital and Family Approaches; Keith Klostermann; 20. Self-Help Organizations for Substance Use Disorders; Anna Lembke, Keith Humphreys; 21. Pharmacotherapy of Substance Use, Craving, and Acute Abstinence Syndromes; Robert M. Swift; Part Five: Prevention and Policy ; 22. Programs and Policies Designed to Reduce Impaired Driving; Robert Voas, James C. Fell; 23. Prevention and Intervention in the School Setting; Elizabeth J. D'Amico, Karen Chan Osilla, Stefanie A. Stern; Part Six: Concluding Commentary; 24. Anticipating the Future of Research on Substance Use and Substance Use Disorders; Kenneth J. Sher, Alvaro A. Verges; Index