The term "natural products" spans an extremely large and diverse range of chemical compounds derived and isolated from biological sources. Our interest in natural products can be traced back thousands of years for their usefulness to humankind, and this continues to the present day. Compounds and extracts derived from the biosphere have found uses in medicine, agriculture, cosmetics, and food in ancient and modern societies around the world. Therefore, the ability to access natural products, understand their usefulness, and derive applications has been a major driving force in the field of natural product research. The first edition of Natural Products Isolation provided readers for the first time with some practical guidance in the process of extraction and isolation of natural products and was the result of Richard Cannell's unique vision and tireless efforts. Unfortunately, Richard Cannell died in 1999 soon after completing the first edition. We are indebted to him and hope this new edition pays adequate tribute to his excellent work. The first edition laid down the "ground rules" and established the techniques available at the time. Since its publication in 1998, there have been significant developments in some areas in natural product isolation. To capture these developments, publication of a second edition is long overdue, and we believe it brings the work up to date while still covering many basic techniques known to save time and effort, and capable of results equivalent to those from more recent and expensive techniques.
Rezensionen / Stimmen
"... offers extensive help in the selection of a suitable methodology...an excellent aid...closes a painfully evident gap in the selection of monographs on natural products chemistry...warmly recommended to anyone interested in the isolation of natural products."-Angewandte Chemie "...a very good general reference that concentrates a considerable amount of useful practical information...well worth considering as a reference for graduate students or other researchers who might need to familiarize themselves with the intricacies of the subject."-Journal of Natural Products "...contains a wealth of practical information, hints, and useful points...an asset in any laboratory where natural products isolation is performed." -Journal of Medicinal Chemistry "...a very good general reference that concentrates a considerable amount of useful practical information." -Pathology "...excellent and comprehensive...wholeheartedly recommend[ed]...as a comprehensive handbook for solving problems in daily research." -Drug Discovery Today
Reihe
Auflage
Sprache
Verlagsort
Zielgruppe
Für Beruf und Forschung
Research
Editions-Typ
Produkt-Hinweis
Illustrationen
133
133 s/w Abbildungen
1, black & white illustrations
Maße
Höhe: 23.5 cm
Breite: 15.5 cm
Dicke: 28 mm
Gewicht
ISBN-13
978-1-58829-447-0 (9781588294470)
DOI
Schweitzer Klassifikation
Natural Product Isolation: An Overview
Satyajit D. Sarker, Zahid Latif, and Alexander I. Gray
Initial and Bulk Extraction
Véronique Seidel
Supercritical Fluid Extraction
Lutfun Nahar and Satyajit D. Sarker
An Introduction to Planar Chromatography
Simon Gibbons
Isolation of Natural Products by Low-Pressure Column Chromatography
Raymond G. Reid and Satyajit D. Sarker
Isolation by Ion-Exchange Methods
David G. Durham
Separation by High-Speed Countercurrent Chromatography
James B. McAlpine and Patrick Morris
Isolation by Preparative High-Performance Liquid Chromatography
Zahid Latif
Hyphenated Techniques
Satyajit D. Sarker and Lutfun Nahar
Purification by Solvent Extraction Using Partition Coefficient
Hideaki Otsuka
Crystallization in Final Stages of Purification
Alastair J. Florence, Norman Shankland, and Andrea Johnston
Dereplication and Partial Identification of Compounds
Laurence Dinan
Extraction of Plant Secondary Metabolites
William P. Jones and A. Douglas Kinghorn
Isolation of Marine Natural Products
Wael E. Houssen and Marcel Jaspars
Isolation of Microbial Natural Products
Russell A. Barrow
Purification of Water-Soluble Natural Products
Yuzuru Shimizu and Bo Li
Scale-Up of Natural Product Isolation
Steven M. Martin, David A. Kau, and Stephen K. Wrigley
Follow-Up of Natural Product Isolation
Richard J. P. Cannell
Index