Part I: Introduction, Evaluation, Treatment.- Health Services for Addiction Treatment and Levels of Care.- Laboratory Testing for Substance Use Disorders.- Epidemiology, genetics, and neurobiology of substance use and disorders.- Screening, Evaluation and Diagnosis of Substance Use Disorder.- Psychosocial Treatment of Substance Use Disorders.- Recovery from Addiction: Maintenance and Preventing Relapse.- Part II: Addictions and their Treatments.- Nicotine.- Alcohol.- Benzodiazepines and other Sedatives, Hypnotics, and Anxiolytics.- Cannabinoids.- OPIOIDS.- Stimulants: Caffeine, Cocaine, Amphetamine and Other Stimulants.- Steroids, Dissociatives, Club Drugs, Inhalants, and Hallucinogens.- Behavioral Addiction.- Part III: Populations.- Adolescents and Students.- Women and Pregnancy.- Lesbian, Gay, Bisexual, Transgender, Queer or Questioning, Intersex, Asexual or Allied.- Underserved Populations.- Older Adults.- Professionals.- Part IV: Other Topics.- Co-occurring Medical Disorders.- Co-occurring Psychiatric Disorders.- Prevention, Public Health, and Public Policy.- Ethical and Legal Considerations.