Pediatric Inflammatory Bowel Disease
Beschreibung
Pediatric Inflammatory Bowel Disease, Second Edition provides an essential reference with an emphasis on the unique pediatric issues of IBD. Chapters focus on complications of IBD specific to children and adolescents. Treatment recommendations are based on the latest clinical research available. The textbook also presents sections dedicated to the aspects of participation in clinical research unique to children and adolescents and the complicated yet vital process of successfully transitioning a patient from a pediatric to adult specialist. Controversies in pediatric IBD care such as the off-label use of medications are also covered. The format incorporates multiple tables, graphs, and figures to improve readability and make for an efficient reference for clinicians to use.
Thoroughly revised and updated from the first edition, the volumes includes new therapies that are currently being used or tested for treatment of IBD, important areas regarding incidence and prevalence, immunization and response to vaccine administration as well as advancements in our understanding of growth and development with particular to the use of growth hormone therapy. Other new areas covered include important topics of complementary and alternative medicine use in IBD, immunization, and liver disease in IBD. Pediatric Inflammatory Bowel Disease, Second Edition is a valuable resource for pediatric gastroenterologists as well as adult gastroenterologists.
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Petar Mamula, MD
Division of GI, Hepatology and Nutrition, The Children's Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA
Jonathan E. Markowitz, MD, MSCE
Greenville Children's Hospital, Pediatric Gastroenterology and Nutrition, University of South Carolina School of Medicine--Greenville, Greenville, SC, USA
Robert N. Baldassano, MD
Division of GI, Hepatology and Nutrition, The Children's Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA
Inhalt
Section 1: Etiology and Pathogenesis
1. Genetics of Inflammatory Bowel Disease
Zhi Wei, Steven Baldassano and Hakon Hakonarson
2. Gut Immunity and Inflammatory Bowel Disease
William A. Faubion
3. Cytokines and Inflammatory Bowel Disease
Edwin F. de Zoeten and Ivan J Fuss
4. The Gut Microbiota and IBD
Judith Kelsen and Gary D. Wu
Section 2: Epidemiology and Clinical Features
5. Epidemiology of Pediatric Inflammatory Bowel Disease
Shehzad Saeed and Subra Kugathasan
6. Early Onset Inflammatory Bowel Disease
Melvin B. Heyman and Neera Gupta
7. The Natural History of Crohn Disease in Children
James F. Markowitz
8. Natural History of Ulcerative Colitis in Children
Jeffrey S. Hyams
9. Natural History of Indeterminate Colitis
Mary K. Rogers Boruta, Richard J. Grand and Michael D. Kappelman
10: Extraintestinal Manifestations of Pediatric Inflammatory Bowel Disease
Shervin Rabizadeh and Maria Oliva-Hemker
11. Liver Disease in Pediatric Inflammatory Bowel Disease
Pamela L. Valentino and Binita M. Kamath, MBBChir
12. Growth Impairment in Pediatric Inflammatory Bowel Disease
Thomas D Walters and Anne Griffiths
13. Inflammatory Bowel Diseases and Skeletal Health
Francisco A. Sylvester
14. Puberty and Pediatric-Onset Inflammatory Bowel Disease
Dianne Deplewski and Barbara S. Kirschner
15. Classification of Inflammatory Bowel Disease in Children
Athos Bousvaros
Section 3: Diagnosis
16. The History and Physical Exam
Alka Goyal and David J. Keljo
17. Differential Diagnosis of Inflammatory Bowel Disease
Thierry Lamireau
18. Laboratory Evaluation of Inflammatory Bowel Disease
Jennifer Strople and Benjamin D. Gold
19. Radiologic Evaluation of Pediatric Inflammatory Bowel Disease
Stephen M. Druhan and Benedict C. Nwomeh
20. Endoscopic Modalities in Pediatric Inflammatory Bowel Disease
K Venkatesh and Mike Thomson
21. The Pathology of Chronic Inflammatory Bowel Disease
Pierre Russo
22. Videocapsule Endoscopy in Inflammatory Bowel Disease
Ernest G. Seidman
23. Bone Health in Pediatric Inflammatory Bowel Disease
Meena Thayu and Edisio Semeao
24. Assessment of Growth and Nutritional Status in Children with Inflammatory Bowel Disease
Babette Zemel
Section 4: Medical Therapy
25. Pharmacogenetics in IBD
Marla C. Dubinsky
26. 5-Aminosalicylate Therapy
Michael Stephens and Alisha M. Mavis
27. Antibiotic Therapy
Howard Kader, Douglas Jacobstein and Adam Paul
28. Nutritional Management of Inflammatory Bowel Disease
Anthony Otley, Andrew S Day and Mary Zachos
29. Probiotic Therapy
David R. Mack
30. Corticosteroids
Johanna C. Escher
31. 6-Mercaptopurine Therapy
Carmen Cuffari
32. Methotrexate
Joel R. Rosh
33. Infliximab Therapy for Pediatric Crohn Disease and Ulcerative Colitis
Ilse Hoffman, Tania Claeys, Severine Vermeire, Gert Van Assche, Peter Witters and Paul Rutgeerts
34. Biologic Therapies
Wojciech Blonski, Faten Aberra and Gary R. Lichtenstein
35. Medical Treatment of Perianal Crohn Disease Fistulae
Mark T. Osterman and Gary R. Lichtenstein
36. Management of Fulminant Colitis
Harland Winter
Section 5: Surgical Therapy
37. Surgical Management of Crohn Disease in Children
David von Allmen
38. Surgical Treatment of Ulcerative Colitis
Peter Mattei
39. Pouchitis After Ileal Pouch-Anal Anastomosis
Victor Uko and Robert Wyllie
40. Enteral Feeding Devices and Ostomies
Susan N. Peck
Section 6: Research
41. Clinical Indices for Pediatric Inflammatory Bowel Disease Research
Angela Noble and Dan Turner
42. Clinical Trials (Clinician Perspective)
Salvatore Cucchiara, Giovanni DiNardo and Marina Aloi
43. Clinical Trials (Industry Perspective)
Allan Olson
Section 7: Special Considerations
44. Psychological Aspects of IBD in Children and Adolescents
Laura M. Mackner and Wallace V. Crandall
45. Measurement of Quality of Life in Pediatric Inflammatory Bowel Disease
Anthony Otley
46. Irritable Bowel Syndrome and Functional Gastrointestinal Disorders in Pediatric Inflammatory Bowel Disease
Khalil El-Chammas and Manu R. Sood
47. Inflammatory Bowel Disease in Pregnancy
Sunanda Kane
48. Immunizations in the Child with Inflammatory Bowel Disease
Athos Bousvaros and Ying Lu
49. Malignant Tumors Arising in Inflammatory Bowel Disease
Thomas A. Ullman
50. Quality Improvement in Inflammatory Bowel Disease
Richard Colletti, Michael D. Kappelman, Wallace V. Crandall and Peter A. Margolis
51. Advocacy for Pediatric Patients with IBD
Janis Arnold, Athos Bousvaros and Jennifer C. Jaff
52. Legislative Advocacy
Crohn's & Colitis Foundation of America
53. Transition from Pediatric to Adult Care
Bincy P. Abraham and George D. Ferry