Introduction: cost analysis on the medical prescription of narcotics; definition of the problem - general situation, scientific program, objectives; methods -scope of the study, procedure, types of costs, validation of the results; results, including project comparisons -introduction, total costs, direct costs, labour costs, other operating costs (material costs), revenues, conclusions; recommendations; appendix; socio-economic evaluation of the trials for the medical prescription of opiates; overview; introduction - the PROVE trials, scientific program, socioeconomic evaluation, present state of research; rationale/hypotheses - housing, work, legal behaviour; methodology - theoretical concept, practical implementation, data sources, cohorts studied; housing - data sources, resource use, valuation, calculation of benefits, results, discussion; work - data resources, working time, valuation, results, discussion; legal behaviour - data sources, effects, valuations, results, discussion; health - data resources, number of diagnoses, comparison method, assessment of costs per diagnosis, results, discussion; general outlook -introduction, cost of the PROVE trials, overall benefit per participant and day, comparison of costs and benefits; literature. Subject index.
