This handbook comprises the recent non-classical synthetic methods for the separation of racemic mixtures in one handy volume, allowing an easy comparison of the different strategies described in the literature. It offers a thorough introduction to the field plus a long-needed up-to-date overview of chemical, biological and physical methods and their applications. Newcomers to the field, students as well as experienced synthetic chemists will benefit from the highly didactic presentation: every method is presented in detail, from relatively simple separation problems to advanced complex resolution methods.
Sprache
Verlagsort
Zielgruppe
Für höhere Schule und Studium
Für Beruf und Forschung
Maße
Höhe: 240 mm
Breite: 170 mm
ISBN-13
978-3-527-30502-5 (9783527305025)
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Schweitzer Klassifikation
Dr. Jason Eames received his Ph.D. in 1996 at Pembroke College, Cambridge. After working at Zeneca, Macclesfield, and as a postdoctoral research fellow at the Universitiy of Oxford he started lectureship at St. Hilda-s College, Oxford University in 1997 and is now lecturer in organic chemistry at Queen Mary and Westfield College, University of London. Matthew Todd is lecturer in organic chemistry at the Queen Mary University of London where he focuses his research on stereoselective synthesis of peptidomimetics, catalysis and combinatorial chemistry.
INTRODUCTION: CONCEPTS PART I: NEW SYNTHETIC METHODS Kinetic Resolutions Catalytic Kinetic Resolutions Sequential and Tandem Kinetic Resolutions Dynamic Kinetic Resolutions Parallel Kinetic Resolutions Mutual Kinetic Resolutions Indirect Resolution Methods PART II: NEW BIOLOGICAL AND PHYSICAL METHODS Kinetic Resolutions using Enzymes Biological Mimics New Physical Methods PART III: APPLICATIONS AND CONCLUSION Application of New Resolution Methods Conclusion
