Updated and revised, this best-selling title provides a current overview from an analytical chemist's point of view. The authors are experienced analytical chemists themselves and thus know exactly how to explain the complex statistics. They are also able to discuss the practicalities and provide many helpful practical hints, making this book unique compared to other works in the field. Following an introductory chapter, the book devotes one section each to the four phases of quality assurance: establishing the quality characteristics of a new method, making the process operational, use of the process through routine analysis, and external QA through interlaboratory comparisons and audits. A final chapter provides the necessary definitions. This new to edition reflects the latest developments, including several changes and updates due to the recent changes in standardization, as well as around 15% completely new content. The accompanying CD contains interactive examples as Excel spreadsheets for learning by doing. These allow readers to gain en even better understanding of the statistical procedures by incorporating their own data.
Auflage
Sprache
Verlagsort
Zielgruppe
Editions-Typ
Maße
Höhe: 240 mm
Breite: 170 mm
ISBN-13
978-3-527-33481-0 (9783527334810)
Copyright in bibliographic data is held by Nielsen Book Services Limited or its licensors: all rights reserved.
Schweitzer Klassifikation
The late Werner Funk was professor at the University of Applied Sciences in Giessen-Friedberg (Germany). Vera Dammann is a senior scientist at the University of Applied Sciences in Giessen-Friedberg (Germany) since 1978. She has been working in areas such as computing, electrical engineering, electrical and biophysical measurement technology and clinical engineering. She is project manager for the international course 'Clinical Engineering' and a member of the board of the German Association for Biomedical Instrumentation. Gerhild Donnevert is laboratory engineer in the laboratory for analytical chemistry at the University of Applied Sciences in Giessen-Friedberg (Germany). She is an active member of the German standardization committees for the examination of water, wastewater and sludge as well as of the Technical Committee 147 'Water Quality' of the International Standards Organization ISO.
INTRODUCTION General differentiation of analytical processes Quality of analytical processes and results The system of analytical quality assurcane The 4-phase model of analytical quality assurance PHASE I: ESTABLISHING A NEW ANALYTICAL PROCESS Calibration of the fundamental analytical procedure Analyses at very low concentrations Validation of individual process steps and examination of matrix influences Advanced statistical methods Use of internal standards Preparing for routine analysis PHASE II: PREPARATIVE QUALITY ASSURANCE Selection of the analytical process Establishment of quality objectives to be adhered to in routine usage The control chart system Types of control charts and their applications PHASE III: ROUTINE QUALITY ASSURANCE Fundamental measured of internal quality assurance Measurement uncertainty Routine quality control Special quality problems in routine analysis Corrective measures Documentation and archiving PHASE IV: EXTERNAL ANALYTICAL QUALITY ASSURANCE Review, Audit Interlaboratory tests Effects of internal quality assurance on the results of interlaboratory tests
