Organic chemistry is one of the most rapidly growing sciences. There is a wide variety of applications of organic compounds, for instance, pharmaceutically active substances, agrochemicals, optoelectronics, etc. Within this group there are hundereds and thousands of new compounds synthesized or isolated from natural sources. Such important organic chemistry developments are accompanied by the profound break-through of new reactions, increasingly efficient methodologies, reagents and catalysts. The chemistry of biaryls is one of the most interesting fields in organic chemistry, this book looks at these reactions both new and old. Synthesis of Biaryls presents the description of a given method for the synthesis of biaryls: short introduction, reaction mechanism, application, representative synthetic procedures, conclusion and literature references. This book will be of interest to organic chemists in industry and academia.
Rezensionen / Stimmen
"The writing and preparation of this book has clearly been a labor of love for Dr. Cepanec. He has provided exhaustive coverage of the old and the new, critically analyzed and compared the methods, provided data on best conditions for first attempts, given mechanistic insight as it relates to synthetic optimization, and listed selected synthetic procedures, some from direct experience, for use in the lab. The text is clear, the equations are instructive, with more than the normal details of conditions, and the index is substantial and carefully constructed. The field of aryl-aryl coupling is omnipresent in chemical synthesis and is therefore required knowledge for the modern practicing chemist. This volume not only provides that knowledge and examples of its applications, it also fosters an appreciation of biaryl synthesis." --Victor Snieckus, Queen's University
Sprache
Verlagsort
Verlagsgruppe
Elsevier Science & Technology
Zielgruppe
Für Beruf und Forschung
All research chemists, undergraduate, postgraduate and practitioners in the field of organic chemistry
Maße
Höhe: 240 mm
Breite: 165 mm
Gewicht
ISBN-13
978-0-08-044412-3 (9780080444123)
Copyright in bibliographic data and cover images is held by Nielsen Book Services Limited or by the publishers or by their respective licensors: all rights reserved.
Schweitzer Klassifikation
Autor*in
Director of Research & Development Department
BELUPO Pharmaceuticals Inc., Zagreb, CROATIA
1. Introduction.
2. Classical Methods For Synthesis Of Biaryls.
3. Coupling Reactions Of Aryl Halides And Sulfonates With Metal Complexes And Active Metals.
4. Cross-Coupling Reactions Of Arylmetallic
Reagents With Aryl Halides And Aryl Sulfonates.
5. The Suzuki-Miyaura Reaction.
6. Synthesis Of Biaryls And Polyaryls.
by Oxidative Couplings Of Arenes.
7. Miscellaneous Methods For Synthesis Of Biaryls.
8. Synthesis Of Axially Chiral Biaryls.
