Histamine Receptors
Preclinical and Clinical Aspects
Erschienen am 27. Juni 2018
Buch
Softcover
XIV, 373 Seiten
978-3-319-82074-3 (ISBN)
Beschreibung
A comprehensive and detailed overview of the current state of preclinical research on histamine and histamine receptors. Part of the book focuses on novel approaches to the study of histamine receptors such as polymorphism, genetic linkage, and computational analysis, and on the use of new histaminergic ligands in diseases such as asthma and dermatitis. Several chapters will be devoted to the role of histamine in the control of homeostatic and behavioral responses such as the sleep-wake cycle, regulation of the blood brain barrier, food intake, alertness, itch, and memory formation and consolidation.
Weitere Details
Reihe
Auflage
Softcover Reprint of the Original 1st 2016 ed.
Sprache
Englisch
Verlagsort
Cham
Schweiz
Verlagsgruppe
Springer International Publishing
Zielgruppe
Für Beruf und Forschung
Illustrationen
52 farbige Abbildungen, 59 s/w Abbildungen
XIV, 373 p. 111 illus., 52 illus. in color.
Maße
Höhe: 235 mm
Breite: 155 mm
Dicke: 21 mm
Gewicht
587 gr
ISBN-13
978-3-319-82074-3 (9783319820743)
DOI
10.1007/978-3-319-40308-3
Schweitzer Klassifikation
Weitere Ausgaben
Andere Ausgaben
Buch
11/2016
Humana
160,49 €
Artikel ist vergriffen; siehe Neuauflage
Inhalt
Molecular aspects of histamine receptors.- Genetic polymorphisms in the histamine receptor family.- The role of the histamine H4 receptor in asthma and atopic dermatitis.- Identification and roles of zebrafish histamine receptors.- Histamine H3r antagonists: from scaffold hopping to clinical candidates.- Clinical significance of histamine H1 receptor gene expression and drug action of antihistamines.- Histamine and its receptors as a module of the biogenic amine diseasome.- Histaminergic regulation of blood-brain barrier activity.- Histamine function in nervous systems.- Heterogeneity of histaminergic neurons.- Modulation by histamine H3 receptors of neurotransmitter release in the basal ganglia.- Interaction of brain histaminergic and dopaminergic systems.- Histamine H1 Receptor Occupancy in Human Brain Measured by Positron Emission Tomography.- Modulation of memory consolidation and extinction by brain histamine.- Histamine and appetite.