Clinical Research for Surgeons is a practical guide for understanding, planning, conducting, and evaluating surgical research. It covers the principles of evidence-based surgery and applies these principles to the design of suitable research studies. The reader will come to fully understand important concepts such as case-control study, prospective cohort study, randomized trial, and reliability study. The book provides valuable discussions of the critical appraisal of published clinical studies, allowing the reader to learn how to evaluate the quality of such studies with respect to measuring outcomes and to make effective use of all types of evidence in patient care.Highlights:Insights from experienced surgeons and veteran researchers Easy-to-reference text boxes with Key Concepts, Jargon Simplified, and Examples from the Literature Coverage of both open and minimally-invasive surgical procedures 50 illustrations demonstrating key pointsThis book is a valuable reference for clinicians and residents in a range of disciplines, including general surgery, orthopedic surgery, plastic and reconstructive surgery, urology, neurosurgery, otolaryngology-head and neck surgery, interventional radiology, cardiac surgery.
Rezensionen / Stimmen
Praise for this book:
"Readable, relevant, and interesting...this book cuts through jargon, recapitulates key concepts, and clarifies with current examples from the literature...recommend[ed]."--Doody's Review
A thoughtful introduction and guide to clinical research for surgeons. The book is especially useful because surgical research differs from drug and device research in matters like control treatments, blinding, regulation, and funding. -- Norman M. Goldfarb, Journal of Clinical Research Best Practices, August, 2012.
Reihe
Sprache
Verlagsort
Zielgruppe
Für Beruf und Forschung
Ärzte
Editions-Typ
Illustrationen
- 105 Illustrations, color
Maße
Höhe: 27 cm
Breite: 19.5 cm
Gewicht
ISBN-13
978-3-13-143931-4 (9783131439314)
Schweitzer Klassifikation
Part I Why We Need Clinical Research1 Historical Perspective of Clinical Research2 Evidence-Based Surgery Defined3 Myths and Misconceptions about Evidence-Based Medicine4 Becoming and Evidence-Based SurgeonPart II Principles of Clinical Research5 Various Research Design Classifications6 Hierarchy of Research Studies: From Case Series to Meta-Analyses7 Randomized and Nonrandomized StudiesPart IIA Understanding Research Study Design8 The Clinical Case Series9 The Case&ndsah;Control Study10 The Prospective Cohort Study11 The Randomized Trial12 Meta-Analyses13 Economic Analysis14 The Diagnostic Study15 The Reliability StudyPart IIB Understanding Outcomes Measurement16 The Classification of Outcomes17 What Makes an Outcome Measure Useful18 Common Generic Outcome Scales for Surgeons19 Common Disease-Specific Outcome Scales for SurgeonsPart IIC Understanding Treatment Effects20 Common Ways to Present Treatment Effects21 The Confidence Interval Defined22 The P Value Defined23 Errors in Hypothesis Testing24 Clinical versus Statistical SignificancePart III Practice of Clinical ResearchPart IIIA Planning a Research Study25 The Requirements of a Clinical Research Proposal26 The Identification of a Good Research Question27 How to Conduct a Comprehensive Literature Search28 Guide to Planning a Randomized Trial29 Guide to Planning a Nonrandomized Study30 Study Sample Size31 How to Budget for a Research Study32 Research Ethics, Review Boards, and Consent Forms33 Regulatory Issues in the Evaluation of a New Device or Drug34 Strategies in Research FundingPart IIIB Conducting a Research Study35 The Roles of the Research Team36 The Role of a Central Methods Center37 The Role of a Data Monitoring Committee38 The Need for Separate Adjudication of Outcomes39 Data Management40 Study Case Report Forms41 The Study Manual of OperationsPart IIIC Practical Guide to Statistical Analysis42 Review of Basic Statistical Principles43 Statistical Means and Proportions44 Regression Analysis45 Analysis of Variance46 Correlation Defined
