Handbook of the Biology of Aging
9th Edition
Published on 22. January 2021
Book
Paperback/Softback
468 pages
978-0-12-815962-0 (ISBN)
Description
Handbook of the Biology of Aging, Ninth Edition, provides a comprehensive synthesis and review of the latest and most important advances and themes in modern biogerontology. The book focuses on the trend of 'big data' approaches in the biological sciences, presenting new strategies to analyze, interpret and understand the enormous amounts of information being generated through DNA sequencing, transcriptomic, proteomic, and metabolomics methodologies applied to aging related problems. Sections cover longevity pathways and interventions that modulate aging, innovative tools that facilitate systems-level approaches to aging research, the mTOR pathway and its importance in age-related phenotypes, and much more.
More details
Series
Edition
9th edition
Language
English
Place of publication
San Diego
United States
Publishing group
Elsevier Science Publishing Co Inc
Target group
College/higher education
Clinicians, researchers, and students in gerontology, developmental psychology, psychiatry, biology, and other related health care professions tasked with caring for the aging population.
Product notice
Paperback (trade)
Dimensions
Height: 276 mm
Width: 218 mm
Thickness: 27 mm
Weight
1318 gr
ISBN-13
978-0-12-815962-0 (9780128159620)
Copyright in bibliographic data and cover images is held by Nielsen Book Services Limited or by the publishers or by their respective licensors: all rights reserved.
Schweitzer Classification
Other editions
Additional editions
Nicolas Musi | Peter Hornsby
Handbook of the Biology of Aging
E-Book
01/2021
9th Edition
Academic Press
€115.00
Available for download
Previous edition
Nicolas Musi | Peter Hornsby
Handbook of the Biology of Aging
Book
10/2015
8th Edition
Academic Press
€115.50
Shipment within 15-20 days
Persons
Dr. Nicolas Musi is a tenured Professor of Medicine (Division of Geriatrics and Gerontology and Division of Diabetes) and Director of the Barshop Institute for Longevity and Aging Studies, the San Antonio Claude D. Pepper Older Americans Independence Center, and the San Antonio Geriatric Research, Education and Clinical Center. He is an active educator and research mentor, and supervises clinical and research fellows, residents and graduate students. In this role, he also functions as Director of a T32 Training Grant on the Biology of Aging. Dr. Peter Hornsby obtained a Ph.D. in Cell Biology at the Institute of Cancer Research of the University of London. He has held faculty positions at the University of California SanDiego, the Medical College of Georgia, and Baylor College of Medicine. Currently he is Professor in Department of Physiology and Barshop Institute for Longevity and Aging Studies, University of Texas Health Science Center, San Antonio.
Content
Part I: Basic mechanisms, underlying physiological changes, model organisms and interventions
1. Longevity as a complex genetic trait
2. DNA damage and repair in aging
3. Mechanisms of cell senescence in aging
4. The nature of aging and the geroscience hypothesis
5. Sirtuins, healthspan, and longevity in mammals
6. Integrative genomics of aging
7. Thermogenesis and aging
8. Yeast as a model organism for aging research
9. Model organisms (invertebrates)
10. NIA Interventions Testing Program: A collaborative approach for investigating interventions to promote healthy aging
11. Aging in nonhuman primates
Part II: Organ systems in humans and other animals, human health and longevity
12. Senotherapeutics: Experimental therapy of cellular senescence
13. The role of neurosensory systems in the modulation of aging
14. Aging of the sensory systems: hearing and vision disorders
15. Cardiac aging
16. The aging immune system: Dysregulation, compensatory mechanisms, and prospects for intervention
17. Microbiome changes in aging
18. Lipidomics of aging
19. Trends in morbidity, healthy life expectancy, and the compression of morbidity
1. Longevity as a complex genetic trait
2. DNA damage and repair in aging
3. Mechanisms of cell senescence in aging
4. The nature of aging and the geroscience hypothesis
5. Sirtuins, healthspan, and longevity in mammals
6. Integrative genomics of aging
7. Thermogenesis and aging
8. Yeast as a model organism for aging research
9. Model organisms (invertebrates)
10. NIA Interventions Testing Program: A collaborative approach for investigating interventions to promote healthy aging
11. Aging in nonhuman primates
Part II: Organ systems in humans and other animals, human health and longevity
12. Senotherapeutics: Experimental therapy of cellular senescence
13. The role of neurosensory systems in the modulation of aging
14. Aging of the sensory systems: hearing and vision disorders
15. Cardiac aging
16. The aging immune system: Dysregulation, compensatory mechanisms, and prospects for intervention
17. Microbiome changes in aging
18. Lipidomics of aging
19. Trends in morbidity, healthy life expectancy, and the compression of morbidity