
Body Composition and Aging
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Content
- Cover
- Contents
- Preface
- Contribution of Adipose Tissue to Health Span and Longevity
- Abstract
- Obesity and Disease
- Can Subcutaneous Fat Be Beneficial?
- Obesity and Mortality Risk in Humans
- Role of Adiposity in Caloric Restriction-Mediated Longevity
- Conclusions
- Acknowledgements
- References
- Obesity Paradox during Aging
- Abstract
- Prevalence of Overweight and Obesity among Older People
- Changes in Body Weight and Body Composition with Increasing Age
- Causes of Overweight and Obesity in Older People
- Consequences of Obesity in Older People
- Management of Obesity in Older People
- Conclusions
- References
- Central Control of Food Intake in Aging
- Abstract
- Main Components of Central Regulatory Mechanisms of Food Intake
- Leptin and Central Leptin Resistance during Aging
- Insulin Action on Hypothalamic Centers Controlling Feeding Behavior Is Decreasedin Aging
- Acknowledgement
- References
- Changes in Food Intake and Its Relationship to Weight Loss during Advanced Age
- Abstract
- Introduction
- Declining Food Intake during Aging: The Satiety Factor
- Hypothalamic Correlates of Declining Body Weight during Aging
- Neuropeptide Y
- Gamma-Amino Butyric Acid
- Leptin
- Insulin
- Cholecystokinin
- Conclusion
- Acknowledgements
- References
- Changes in Body Composition in Response to Challenges during Aging in Rats
- Abstract
- Measurement of Body Composition in Aging Rodents
- Body Weights in Three Rat Models of Aging
- Patterns of Body Composition Changes with Normal Aging in Brown Norway Rats
- Changes in Body Composition in Response to Negative Energy Balance
- Surgical Challenge in Senescent Brown Norway Rats
- Metabolic Challenge: 72 Hours of Food Deprivation
- Changes in Body Composition in Response to Positive Energy Balance
- Fat Depot Weights
- Conclusions
- Acknowledgement
- References
- New Haystacks Reveal New Needles: Using Caenorhabditis elegans to Identify Novel Targets for Ameliorating Body Composition Changes during Human Aging
- Abstract
- Introduction to Caenorhabditis elegans
- Muscle Aging and Sarcopenia in C. elegans
- Concluding Remarks
- References
- Sarcopenia: Prevalence, Mechanisms, and Functional Consequences
- Abstract
- Age-Related Decline in Strength
- Age-Related Loss of Skeletal Muscle Mass
- Mechanisms Underlying Sarcopenia
- Age-Related Changes in Power
- Muscle Weakness and Osteoarthritis of the Knee
- References
- mTOR Signaling as a Target of Amino Acid Treatment of the Age-Related Sarcopenia
- Abstract
- Intracellular Mechanisms of Protein Synthesis Regulation: mTOR as a Downstream Target of PKB/Akt
- Much More than Bricks: Branched-Chain Amino Acids as Possible Regulators of Protein Synthesis through the mTOR Pathway
- mTOR Signaling in Aging
- mTOR, Mitochondrial Biogenesis, and Sarcopenia
- References
- Mitochondrial Theory of Aging in Human Age-Related Sarcopenia
- Abstract
- Evidence of the Mitochondrial Theory of Aging in Human Skeletal Muscle
- Resistance Exercise and Mitochondrial Adaptation in Human Skeletal Muscle
- Muscle Stem Cells and Mitochondria: A Crossroads in the Treatment of Age-Related Sarcopenia?
- Muscle Stem Cells
- Perspectives
- References
- Exercise as a Calorie Restriction Mimetic: Implications for Improving Healthy Aging and Longevity
- Abstract
- Exercise, Energy Balance and Longevity in Rodents
- Disparate Effects of Exercise and Calorie Restriction on Longevity: Potential Mechanisms
- Exercise and Longevity in Humans
- Conclusions
- Acknowledgements
- References
- Clinical, Cellular and Molecular Phenotypes of Aging Bone
- Abstract
- Quantitative and Qualitative Changes in the Aging Bone
- Genetics of Peak Bone Mass Accrual in Subsequent Bone Loss with Aging
- Impact of Environmental Factors on Bone Loss with Age
- Patterns of Age-Related Bone Loss in Men and Women
- Murine Models of Normal Aging
- Gonadectomized Models of Bone Loss
- The SAMP6 Mouse: A Model of Impaired Osteoblastogenesis and Bone Formation
- The Klotho-Deficient Mouse: A Model of Disrupted Osteoblasts, Osteoclasts, and Osteocytes and Defects in Mineral Metabolism
- Mouse Models of Laminopathies and Extracellular Matrix Protein Deficiencies
- Mice Genetically Modified for Peptides, Hormones and Transcription Factors: Implications for the Aging Skeleton
- Neural Regulation of the Aging Skeleton
- Cellular and Molecular Changes in Bone Marrow with Aging
- Conclusions
- References
- Author Index
- Subject Index
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The file format PDF always displays a book page identically on any hardware. This makes PDF suitable for complex layouts such as those used in textbooks and reference books (images, tables, columns, footnotes). Unfortunately, on the small screens of e-readers or smartphones, PDFs are rather annoying, requiring too much scrolling.
This eBook uses Adobe-DRM, a „hard” copy protection. If the necessary requirements are not met, unfortunately you will not be able to open the eBook. You will therefore need to prepare your reading hardware before downloading.
Please note: We strongly recommend that you authorise using your personal Adobe ID after installation of any reading software.
For more information, see our eBook Help page.