Metabolic Pathways
3rd Edition
Published on 2. December 2012
512 pages
978-0-323-16213-5 (ISBN)
Description
Metabolic Pathways, Third Edition: Volume IV: Nucleic Acids, Protein Synthesis, and Coenzymes focuses on the metabolic pathways of the major biological constituents of living organisms, namely, nucleic acids, proteins, and coenzymes. The biosynthesis and metabolism of purines and pyrimidines, nucleotides, riboflavin and related compounds, and vitamin B6 are discussed. The biogenesis and metabolism of thiamine and folic acid are also considered. This volume is comprised of seven chapters and begins with an analysis of metabolic control and enzymology of purines and pyrimidines such as inosinic acid and nucleotides. The next chapter is devoted to the biosynthesis and metabolism of nucleotides and nucleic acids, making reference to deoxyribonucleotides as well as RNA and DNA. Some of the reactions involving nucleotides are classified and briefly discussed. The reader is then introduced to protein synthesis, paying particular attention to the chemical features of the synthesis of the peptide bond and the characteristics of the genetic code implicated in this process. The remaining chapters focus on riboflavin and related compounds, thiamine, folic acid, and vitamin B6. This book will be a useful resource for biochemists and biologists.
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D.M. Greenberg
Metabolic Pathways: v. 4
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12/1967
3rd Edition
Academic Press
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05/2014
2nd Edition
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Content
PrefaceList of ContributorsContents of Other VolumesChapter 19 Purines and Pyrimidines Glossary I. Introduction II. Biosynthesis of Inosinic Acid III. Metabolism of Purine Derivatives IV. Biosynthesis of Pyrimidine Nucleotides V. Pyrimidine Catabolism VI. Control of Pyrimidine Metabolism-Summary ReferencesChapter 20 Nucleotides and Nucleic Acids I. General Introduction II. Ribonucleotide Metabolism III. Biosynthesis of Deoxyribonucleotides IV. Metabolism of Deoxyribonucleotides V. Ribonucleic Acid VI. Deoxyribonucleic Acid (DNA) VII. Biosynthesis of Nucleic Acids VIII. Nucleotides as Allosteric Effectors IX. Coenzymes and Group Activation ReferencesChapter 21 Protein Synthesis I. Introduction II. A General Model of Protein Synthesis III. Synthesis of Aminoacyl-tRNA IV. Ribosome Structure V. Binding of Aminoacyl-tRNA to Ribosomes VI. The Genetic Code VII. Initiation VIII. Elongation IX. Termination X. Conclusions References Addendum Addendum ReferencesChapter 22 Biosynthesis of Riboflavin and Related Compounds I. Introduction II. Flavinogenic Microorganisms III. Mechanism of Biosynthesis of Riboflavin IV. Riboflavin 5'-Phosphate (FMN) V. Flavin Adenine Dinucleotide (FAD) ReferencesChapter 23 Biogenesis and Metabolism of Thiamine I. Introduction II. Functions of Thiamine III. Biogenesis of Thiamine and Thiamine Pyrophosphate IV. Thiaminases V. Addendum ReferencesChapter 24 Biogenesis and Metabolism of Folic Acid I. Biogenesis of Folic Acid and Related Compounds II. Formation of Metabolically Functional Forms of Folic Acid III. Addendum ReferencesChapter 25 Metabolism of Vitamin B6 I. Introduction II. Biosynthesis III. Catabolism ReferencesAuthor IndexSubject Index
