Comprehensive Organic Synthesis
Elsevier (Publisher)
3rd Edition
Published on 12. September 2025
9500 pages
978-0-323-96024-3 (ISBN)
Available for download
Description
Comprehensive Organic Synthesis will build upon the highly respected previous editions - the 2nd edition won the 2015 PROSE Award for Multivolume Reference/Science from the Association of American Publishers - in drawing together the new common themes that underlie the many disparate areas of organic chemistry. These themes support effective and efficient synthetic strategies, thus providing a comprehensive overview of this important discipline.
Fully revised and updated, comprising of over 220 advanced chapters, this new edition will continue to constitute an essential reference work for all those seeking information on the solution of synthetic problems, whether they are experienced practitioners or chemists whose major interests lie outside organic synthesis. In addition, synthetic chemists requiring the essential facts in new areas, as well as students completely new to the field, will find Comprehensive Organic Synthesis, Third Edition an invaluable source, providing an authoritative overview of core concepts
- Provides a completely revised and expanded new edition of the renowned Comprehensive Organic Synthesis series
- Contains around 200 advanced chapters, each written by distinguished chemists from across the globe who offer in-depth and detailed analysis of core topics such as bonds, oxidation, and reduction
- Includes more than 10,000 schemes and images
- Follows a consistent structure and features elements such as key objective boxes, summaries, figures, references, cross-references, etc.
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Content
1. Additions to C-X p-Bonds: comprehensive coverage of reactions involving carbon-bond formation with various substituents2. Carbon-Carbon Bond Formation: fundamental methods for forming carbon-carbon bonds, essential for synthetic organic chemistry3. Heteroatom Manipulation: techniques for introducing and modifying heteroatoms in organic molecules4. Oxidation: various methodologies for oxidizing organic compounds, a cornerstone of synthetic transformations5. Reduction: detailed approaches for reducing functional groups, providing essential strategies for chemists6. Asymmetric Synthesis: methods for producing enantiomerically enriched compounds, increasingly important in pharmaceuticals7. Photocatalysis: utilization of light to drive chemical reactions, highlighting innovative and sustainable synthetic strategies8. Electrochemistry: emerging techniques for organic synthesis using electrochemical methods, signifying advancements in green chemistryNew Areas of Coverage in the 3rd Edition:1. C-H Activation: new strategies for activating C-H bonds, enabling direct functionalization of hydrocarbons2. Flow Chemistry: Innovative techniques for continuous flow synthesis, enhancing efficiency and scalability in organic synthesis3. Dual Catalysis: recent developments in using two catalysts simultaneously for complex transformations4. Biosynthesis: exploration of natural product synthesis through biological pathways, bridging organic chemistry and biochemistry5. Catalytic Oxidation: Advanced methodologies for oxidation processes using modern catalytic systems6. Photocatalysis: expanded focus on light-driven reactions, reflecting growing interest in sustainable and energy-efficient methods7. Metal Catalysis: new approaches involving transition metals in catalysis, emphasizing their role in modern synthetic strategies8. Asymmetric Synthesis: enhanced coverage of methods to achieve enantioselectivity in synthetic routes
