Quantitative Structure-Activity Relationship (QSAR) Models of Mutagens and Carcinogens
Published on 26. February 2003
304 pages
978-0-203-01082-2 (ISBN)
Description
Applied with success in a number of areas, QSAR studies have become particularly popular in the rational design of drugs and pesticides. Much has been published on the principles of QSAR in this area, but not on their application s to toxic chemicals.
This book provides the first comprehensive, interdisciplinary presentation of QSAR studies on
This book provides the first comprehensive, interdisciplinary presentation of QSAR studies on
More details
Language
English
Place of publication
Baton Rouge
United States
Publishing group
Taylor & Francis Inc
Target group
Professional and scholarly
Medicinal chemists, Theoretical and computational chemists and biochemists, Scientists in regulatory bodies, Cancer researchers, Toxicologists
Illustrations
43 s/w Abbildungen, 30 s/w Tabellen
43 b/w images and 30 tables
File size
2,33 MB
ISBN-13
978-0-203-01082-2 (9780203010822)
Copyright in bibliographic data and cover images is held by Nielsen Book Services Limited or by the publishers or by their respective licensors: all rights reserved.
Schweitzer Classification
Other editions
Additional editions
Romualdo Benigni
Quantitative Structure-Activity Relationship (QSAR) Models of Mutagens and Carcinogens
Book
02/2003
1st Edition
CRC Press
€285.21
Article exhausted; check different version
Persons
Editor
Instituto Superiore Di Sanita, Roma, Italy
Contributions
Consulting in Drug Design GbR, Basdorf, Germany Consulting in Drug Design GbR, Basdorf, Germany
U.S. EPA, Washington D.C., USA
Instituto Superiore di Sanita, Rome, Italy Instituto Superiore di Sanita, Rome, Italy
U.S. EPA, Research Triangle Park, North Carolina, USA
Florida Atlantic University, Boca Raton, Florida, USA
University of Minnesota, Duluth, Minnesota, USA
Liverpool John Moores University, UK
Consulting in Drug Design GbR, Basdorf, Germany Consulting in Drug Design GbR, Basdorf, Germany
U.S. EPA, Washington D.C., USA
Content
General Introduction to QSAR R. Franke and A. Gruska Mechanisms of Action of Chemical Carcinogens and their Role in Structure-Activity Relationships (SAR) Analysis and Risk Assessment Yin-Tak Woo and David Y. Lai QSARs for Individual Classes of Chemical Mutagens and Carcinogens L. Passerini QSARs for the Mutagenicity and Carcinogenicity of the Aromatic Amines R. Benigni, A. Giuliani, A. Gruska, R. Franke Public Sources of Mutagenicity and Carcinogenicity Data: Use in Structure-Activity Relationship Models A. M. Richard and C. R. Williams SAR in the Assessment of Carcinogenesis: the MultiCASE Approach H.S. Rosenkranz Predicting Mutagenicity of Congeneric and Diverse Sets of Chemicals Using Computed Molecular Descriptors: A Hierarchical Approach S.C.Basak, D. Mills, B.D. Gute, D. M. Hawkins Quantitative Structure-Activity Relationships for Acute Aquatic Toxicity: the Role of Mechanisms of Toxic Action in Successful Modelling M T.D. Cronin SARs and QSARs of Mutagens and Carcinogens: Understanding Action Mechanisms And Improving Risk Assessment R. Benigni
