Fundamentals of Forensic DNA Typing
Published on 30. September 2009
519 pages
978-0-08-096176-7 (ISBN)
Description
Fundamentals of Forensic DNA Typing is written with a broad viewpoint. It examines the methods of current forensic DNA typing, focusing on short tandem repeats (STRs). It encompasses current forensic DNA analysis methods, as well as biology, technology and genetic interpretation. This book reviews the methods of forensic DNA testing used in the first two decades since early 1980's, and it offers perspectives on future trends in this field, including new genetic markers and new technologies. Furthermore, it explains the process of DNA testing from collection of samples through DNA extraction, DNA quantitation, DNA amplification, and statistical interpretation. The book also discusses DNA databases, which play an important role in law enforcement investigations. In addition, there is a discussion about ethical concerns in retaining DNA profiles and the issues involved when people use a database to search for close relatives. Students of forensic DNA analysis, forensic scientists, and members of the law enforcement and legal professions who want to know more about STR typing will find this book invaluable.
- Includes a glossary with over 400 terms for quick reference of unfamiliar terms as well as an acronym guide to decipher the DNA dialect
- Continues in the style of Forensic DNA Typing, 2e, with high-profile cases addressed in D.N.A.Boxes-- "Data, Notes & Applications" sections throughout
- Ancillaries include: instructor manual Web site, with tailored set of 1000+ PowerPoint slides (including figures), links to online training websites and a test bank with key
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John M. Butler
Fundamentals of Forensic DNA Typing
Book
09/2009
Academic Press
€50.00
Shipment within 15-20 days
Persons
John M. Butler is a NIST Fellow and Special Assistant to the Director for Forensic Science, Office of Special Programs, at the U.S. National Institute of Standards and Technology, in Gaithersburg, Maryland. Dr. Butler earned his PhD from the University of Virginia while doing DNA research in the FBI Laboratory's Forensic Science Research Unit. He has won numerous scientific awards, including being named Science Watch's #1 world-wide high-impact author in legal medicine and forensic science over the last decade (July 2011). He has over 150 publications in this field and is a frequent presenter on the topic of DNA typing, and has authored four other DNA Typing books including Advanced Topics in Forensic DNA Typing: Methodology. For a detailed CV, visit cstl.nist.gov/strbase/butler.htm.
Content
Foreword IntroductionAcknowledgmentsAbout the author 1 Overview and History of DNA Typing 2 Basics of DNA Biology and Genetics3 Historical Methods4 Sample Collection, Storage and Characterization5 DNA Extraction6 DNA Quantitation7 DNA Amplification (The Polymerase Chain Reaction)8 Short Tandem Repeat Markers9 Fundamentals of DNA separation and Detection10 STR Genotyping and Data Interpretation11 Statistical Interpretation: Evaluating the Strength of Forensic DNA Evidence12 DNA databases13 Quality Assurance14 Forensic Challenges: Degraded DNA, Mixtures, and LCN15 Additional Loci and Non-Human DNA Testing16 Lineage Markers: Y Chromosome and mtDNA Testing17 Applications of DNA Typing18 Future TrendsAppendix 1 Glossary of Terms2 Useful Websites3 Probability and Statistics
