
Advances in Protein Chemistry
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Content
- Cover
- Contents
- Chapter 1. Physical Principles of Protein Crystallization
- I. Introduction
- II. Stages of Crystal Growth
- III. Driving Forces for Crystal Growth
- IV. Nucleation
- V. Crystal Growth Mechanisms
- VI. Competition between Nucleation and Growth
- VII. Cessation of Growth and Crystal Disorder
- VIII. Crystallization Methods
- IX. Protein Purity
- X. Searching for Crystallization Conditions
- XI. New Developments in Protein Crystallization
- XII. Summary Remarks
- References
- Chapter 2. Protein Hydration and Function
- I. Introduction
- II. Thermodynamics
- III. Dynamics
- IV. Structure
- V. Computer Simulation
- VI. Picture of Protein Hydration
- VII. Hydration and Function
- VIII. Conclusion
- Appendix: Percolation Theory
- References
- Chapter 3. Lysozyme and a-Lactalbumin: Structure, Function, and Interrelationships
- I. Introduction
- II. Early History
- III. Some Aspects of the Occurrence, Isolation, and Characterization of Lysozyme and a-Lactalbumin
- IV. Three-Dimensional Structure of Lysozyme
- V. Three-Dimensional Structure of a-Lactalbumin
- VI. Comparative Binding of Metal Ions in Lysozyme and a-Lactalbumin
- VII. Amino Acid Composition and Sequence Homologies in Lysozymeand a-Lactalbumin
- VIII. Galactosyltransferase and the Lactose Synthase System
- IX. Some Additional Physical, Chemical, and Biological Comparisons between Lysozyme and a-Lactalbumin
- X. Evolutionary Origins of Lysozyme and a-Lactalbumin
- XI. Conclusions and the Future
- References
- Note Added in Proof
- Author Index
- Index
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