Bioseparation and Bioprocessing
A Handbook
2nd Edition
Published on 19. September 2007
Book
Hardback
XXVIII, 770 pages
978-3-527-31585-7 (ISBN)
Description
In this new edition of the only resource to systematically cover all post-production issues, over 70 % of the content is new or rewritten in line with the rapidly evolving technology in the field. By combining the experience of academic experts, managers from the pharmaceutical and biotech industry, as well as independent consultants, biological product recovery is viewed from every possible angle, including biosafety and regulatory issues.
More details
Edition
2., vollständig überarbeitete Auflage
Language
English
Place of publication
Weinheim
Germany
Target group
Professional and scholarly
Edition type
Revised edition
Illustrations
194
12 farbige Abbildungen, 96 s/w Tabellen, 194 s/w Abbildungen
Illustrations
Dimensions
Height: 24 cm
Width: 17 cm
Thickness: 51 mm
Weight
1888 gr
ISBN-13
978-3-527-31585-7 (9783527315857)
Schweitzer Classification
Other editions
Previous edition
Ganapathy Subramanian
Bioseparation and Bioprocessing
A Handbook. Volume I: Biochromatography - Membrane Separations - Modeling - Validation. Volume II: Processing - Quality and Characterisation - Economics, Safety and Hygiene
Book
10/1998
1st Edition
Wiley-VCH
€399.00
Article exhausted; check for reprint
Person
Dr. Ganapathy Subramanian is a biotechnology consultant with over 30 years experience in both industry and academia, in the application and development of processing, purification methodologies and chromatographic systems for large-scale use in environmental science, food science, perfumery cosmetics and pharmaceuticals. He has also taught extensively in the area of food and medical technology.
A chemistry graduate from Madras, India, Dr Subramanian was awarded his Doctorate from the University of Glasgow, for work on natural products, and his main research interests lie in the utilisation of natural material separation processes and bio-conversions.
Dr. Subramanian has written and edited a number of books and articles in the field of biotechnology. For the last 10 years, he has been organizing conferences promoting the integration and sharing of knowledge between academia and industry.
A chemistry graduate from Madras, India, Dr Subramanian was awarded his Doctorate from the University of Glasgow, for work on natural products, and his main research interests lie in the utilisation of natural material separation processes and bio-conversions.
Dr. Subramanian has written and edited a number of books and articles in the field of biotechnology. For the last 10 years, he has been organizing conferences promoting the integration and sharing of knowledge between academia and industry.
Content
VOLUME 1
STRATEGY AND DEVELOPMENT
Process Development: when to start, when to stop
Strategies in downstream processing
BIOPROCESS AND EARLY DSP
Process Development and Optimization for Biotechnology Production -- Monoclonal Antibodies
Dynamics of cellular response to recombinant protein overexpression in Esscherichia coli
PREPARATIVE (CHROMATOGRAPHIC) METHODS
Ion Exchange Chromatography in Biopharmaceutical Manufacturing
Displacement chromatography of biomacromolecules
The Purification of Biomolecules by Countercurrent Chromatography
Continuous chromatography in the down-stream processing of compounds from biotechnological and natural origin
Continuous Annular Chromatography
Principles of membrane separation processes
Affinity Precipitation
VOLUME 2
SPECIFIC BIOPROCESSES AND SEPARATION METHODS
Biological fuel cells
Removal and Analysis of Contaminants and Impurities
High throughput RNAi: Emerging technology for functional Genomics
Developing an Antibody Purification Process
The Many Ways to Purify Plasmis DNA -- Choosing the right purification strategy based on the downstream application
Advanced Fractionation methods and analysis for proteomics applications
SAFETY, QUALITY CONTROL, VALIDATION AND REGUATORY CONSIDERATIONS
Biosafety
The Manufacture of Gene Therapy Products and Viral Vaccines
The Virus and Prion safety of Biopharmaceuticals
Protein Glycosylation: Analysis and Characterization
High Throughput glycoanalysis for use in Bioprocessing
Quality Control of Impantable Drug Delivery Systems?
ANALYTICAL METHODS AND TECHNOLOGIES
Polymerase Chain Reaction: an Analytical Tool in Bioprocessing
Electrokinetic Separations
Capillary Isoelectric Focusing Methods for Charge-Based Analysis of Biopharmaceuticals
STRATEGY AND DEVELOPMENT
Process Development: when to start, when to stop
Strategies in downstream processing
BIOPROCESS AND EARLY DSP
Process Development and Optimization for Biotechnology Production -- Monoclonal Antibodies
Dynamics of cellular response to recombinant protein overexpression in Esscherichia coli
PREPARATIVE (CHROMATOGRAPHIC) METHODS
Ion Exchange Chromatography in Biopharmaceutical Manufacturing
Displacement chromatography of biomacromolecules
The Purification of Biomolecules by Countercurrent Chromatography
Continuous chromatography in the down-stream processing of compounds from biotechnological and natural origin
Continuous Annular Chromatography
Principles of membrane separation processes
Affinity Precipitation
VOLUME 2
SPECIFIC BIOPROCESSES AND SEPARATION METHODS
Biological fuel cells
Removal and Analysis of Contaminants and Impurities
High throughput RNAi: Emerging technology for functional Genomics
Developing an Antibody Purification Process
The Many Ways to Purify Plasmis DNA -- Choosing the right purification strategy based on the downstream application
Advanced Fractionation methods and analysis for proteomics applications
SAFETY, QUALITY CONTROL, VALIDATION AND REGUATORY CONSIDERATIONS
Biosafety
The Manufacture of Gene Therapy Products and Viral Vaccines
The Virus and Prion safety of Biopharmaceuticals
Protein Glycosylation: Analysis and Characterization
High Throughput glycoanalysis for use in Bioprocessing
Quality Control of Impantable Drug Delivery Systems?
ANALYTICAL METHODS AND TECHNOLOGIES
Polymerase Chain Reaction: an Analytical Tool in Bioprocessing
Electrokinetic Separations
Capillary Isoelectric Focusing Methods for Charge-Based Analysis of Biopharmaceuticals