Bioseparation and Bioprocessing
A Handbook. Volume I: Biochromatography - Membrane Separations - Modeling - Validation. Volume II: Processing - Quality and Characterisation - Economics, Safety and Hygiene
1st Edition
Published on 29. October 1998
Book
Hardback
XL, 1012 pages
978-3-527-28876-2 (ISBN)
Description
Rapid developments in biotechnology create a demand for practical, up-to-date reviews written by and for experts in industry. This compact handbook provides all relevant up-to-date information on important bioseparation and bioprocessing techniques that are actively applied in the biotechnology industries. The handbook presents an applications-orientated overview on
- case studies and general strategies for quality control and characterization
- detailed guidelines on developing economic and technically feasible bioseparation schemes
- strategies and methods for intracellular bioproduct release
- chromatographic and membrane downstream processes used in biotechnology
- applications of modern non-invasive methods such as neural networks for on-line estimation and control of fermentation variables on an industrial scale
- a practical, commercially-relevant guide to biosafety
and many more aspects which are indispensible for present and future industrial success.
- case studies and general strategies for quality control and characterization
- detailed guidelines on developing economic and technically feasible bioseparation schemes
- strategies and methods for intracellular bioproduct release
- chromatographic and membrane downstream processes used in biotechnology
- applications of modern non-invasive methods such as neural networks for on-line estimation and control of fermentation variables on an industrial scale
- a practical, commercially-relevant guide to biosafety
and many more aspects which are indispensible for present and future industrial success.
More details
Edition
1., Aufl.
Language
English
Place of publication
Weinheim
Germany
Target group
College/higher education
Professional and scholarly
Illustrations
386
115 s/w Tabellen, 386 s/w Abbildungen
Illustrations
Dimensions
Height: 24 cm
Width: 17 cm
Weight
2267 gr
ISBN-13
978-3-527-28876-2 (9783527288762)
Schweitzer Classification
Other editions
New editions
Book
09/2007
2nd Edition
Wiley-VCH
€365.00
Article is exhausted; no reprint
Content
PROCESSING. Strategies in Downstream Processing (Y. Chisti). Protein Stability in Downstream Processing (K. Hejnaes, et al.). Production of Transgenic Protein (G. Wright & J. Noble). Harvesting Recombinant Protein Inclusion Bodies (A. Middelberg & B. O'Neill). The Application of Glycobiology for the Generation of Recombinant Glycoprotein Therapeutics (J. Damm). The Release of Intracellular Bioproducts (A. Middelberg). Microcarriers in Cell Culture Produktion (B. Lundgren & G. Bloml). Purification and Characterization of Monoclonal Antibodies (P. Matejtschuk, et al. ). QUALITY AND CHARACTERIZATION. Biological Standardization of Interferons and Other Cytokines (A. Meager). The Strategic Role of Assays in Process Development: A Case Study of Matrix-Assisted Laser Desorption Ionization Mass Spectroscopy as a Tool for Biopharmaceutical Development (T. Meyers, et al. ). Quality Control of protein Primary Structure by Automated Sequencing and Mass Spectrometry (P. Jackson & S. Bayne). General Strategies for the Characterization of Carbohydrates from Recombinant Glycoprotein Therapeutics (G. Gerwig & J. Damm). ECONOMICS, SAFETY AND HYGIENE. Biosafety (Y. Chisti). Process Hygiene in Production Chromatography and Bioseparation (G. Kemp). Strategies and Considerations for Advanced Economy in Downstream Processing of Biopharmaceutical Proteins (J. Walter).