Vaccine Protocols
Published on 20. May 1996
Book
Spiral bound
328 pages
978-0-89603-334-4 (ISBN)
Description
Expert practitioners present a comprehensive approach to vaccine development, production, and assessment that can be adapted successfully to any vaccine. Their approach not only includes state-of-the-art techniques for developing live viral and bacterial vectors, expressing foreign vaccine antigens, and producing peptide and conjugate vaccines, but also offers advice and guidance on clinical trials and regulatory requirements. Additional techniques describe such powerful tools as the use of adjuvants, freeze drying vaccines, microencapsulation of vaccines, the full assessment of immunogenicity and potency of vaccines in animal models, and the creation of DNA vaccines, chimeric proteins, and recombinant toxoids.
Reviews / Votes
...a valuable basic reference manual of vaccine related laboratory procedures...strongest in the area of vaccine development and delivery technology...especially valuable to those new to the field of vaccine development and formulation. - Doody's Health Sciences Book Review Journal ...this book should prove to be a valuable aid to all those seeking to produce improved or novel vaccines. - Unlisted DrugsMore details
Series
Language
English
Place of publication
Totowa, NJ
United States
Target group
College/higher education
Professional and scholarly
Product notice
Loose leaf - sheets & binder
Dimensions
Height: 152 mm
Width: 229 mm
Weight
607 gr
ISBN-13
978-0-89603-334-4 (9780896033344)
Copyright in bibliographic data is held by Nielsen Book Services Limited or its licensors: all rights reserved.
Schweitzer Classification
Other editions
New editions
Book
08/2003
2nd Edition
Humana Press Inc.
€160.49
Shipment within 15-20 days
Content
Overview of Vaccines. Temperature-Sensitive Mutant Vaccines. Live Viral Vectors: Construction of a Replication-Deficient Recombinant Adenovirus. Development of Attenuated Salmonella Strains that Express Heterologous Antigens. Chimeric Proteins. Synthetic Peptides. Genetic Detoxification of Bacterial Toxins. Polysaccharide-Conjugate Vaccines. The Use of Adjuvants in Experimental Vaccines: I. Aluminum Hydroxide Gels. The Use of Adjuvants in Experimental Vaccines: II. Water-in-Oil Emulsions: Freund's Complete and Incomplete Adjuvants. The Use of Adjuvants in Experimental Vaccines: III. Liposomes. The Use of Adjuvants in Experimental Vaccines: IV. ISCOMS. Microencapsulation of Vaccines. Lyophilization of Vaccines. Stimulation of Mucosal Immunity. Induction and Detection of T-Cell Responses. Immunological Characterization. Severe Combined Immunodeficient (SCID) Mice in Vaccine Assessment. Clinical Trials. Assuring the Quality of Vaccines: Regulatory Requirements for Licensing and Batch Release. DNA Vaccines. Cancer Vaccines. Index.