A Practical Approach to Toxicological Investigations
Cambridge University Press
Published on 14. December 1989
Book
Hardback
208 pages
978-0-521-34118-9 (ISBN)
Article exhausted; check for reprint
Description
First published in 1989, this book acknowledges that new drugs, food additives and other compounds need to be carefully screened for toxic side-effects. The bulk of this study is devoted to the practical questions of 'what toxicological studies should we perform?' and 'how should we perform them?' Compounds which undergo toxicity testing may be conveniently categorised as those which are intended for administration to man and those which are not. The former include pharmaceuticals to be used medicinally or prophylactically and chemicals which are added to our food, drinks or medicine to improve their stability, appearance or palatability. Since it is on pharmaceuticals that the most comprehensive toxicological evaluations are generally performed, this book has been directed primarily towards to toxicological evaluation of potential new drugs. The principles and methodology of toxicological evaluation of other types of compounds are essentially similar.
More details
Language
English
Place of publication
Cambridge
United Kingdom
Target group
Professional and scholarly
Dimensions
Height: 216 mm
Width: 138 mm
Thickness: 20 mm
Weight
380 gr
ISBN-13
978-0-521-34118-9 (9780521341189)
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Schweitzer Classification
Other editions
New editions

Alan Poole | George B. Leslie
A Practical Approach to Toxicological Investigations
Book
03/2009
Cambridge University Press
€49.20
Shipment within 15-20 days
Additional editions

Alan Poole | George B. Leslie
A Practical Approach to Toxicological Investigations
Book
03/2009
Cambridge University Press
€49.20
Shipment within 15-20 days
Content
1. Introduction; 2. Regulatory requirements; 3. Animals: sources, selection, husbandry; 4. Standard studies in animals; 5. Measurements and observations made in living animals; 6. Terminal studies; 7. Specialised routes of exposure; 8. Reproductive toxicology; 9. Genotoxicity; Appendices; Index.