
A Practical Approach to Toxicological Investigations
Cambridge University Press
Published on 19. March 2009
Book
Paperback/Softback
204 pages
978-0-521-10546-0 (ISBN)
Description
First published in 1989, this book acknowledges that new drugs, food additives and other compounds need to be carefully screened for toxic side-effects. The bulk of this study is devoted to the practical questions of 'what toxicological studies should we perform?' and 'how should we perform them?' Compounds which undergo toxicity testing may be conveniently categorised as those which are intended for administration to man and those which are not. The former include pharmaceuticals to be used medicinally or prophylactically and chemicals which are added to our food, drinks or medicine to improve their stability, appearance or palatability. Since it is on pharmaceuticals that the most comprehensive toxicological evaluations are generally performed, this book has been directed primarily towards to toxicological evaluation of potential new drugs. The principles and methodology of toxicological evaluation of other types of compounds are essentially similar.
More details
Language
English
Place of publication
Cambridge
United Kingdom
Target group
Professional and scholarly
Product notice
Paperback (trade)
Illustrations
Worked examples or Exercises
Dimensions
Height: 216 mm
Width: 140 mm
Thickness: 12 mm
Weight
295 gr
ISBN-13
978-0-521-10546-0 (9780521105460)
Copyright in bibliographic data and cover images is held by Nielsen Book Services Limited or by the publishers or by their respective licensors: all rights reserved.
Schweitzer Classification
Other editions
Additional editions
Alan Poole | George B. Leslie
A Practical Approach to Toxicological Investigations
Book
12/1989
Cambridge University Press
€30.94
Article exhausted; check for reprint
Previous edition
Alan Poole | George B. Leslie
A Practical Approach to Toxicological Investigations
Book
12/1989
Cambridge University Press
€30.94
Article exhausted; check for reprint
Content
1. Introduction; 2. Regulatory requirements; 3. Animals: sources, selection, husbandry; 4. Standard studies in animals; 5. Measurements and observations made in living animals; 6. Terminal studies; 7. Specialised routes of exposure; 8. Reproductive toxicology; 9. Genotoxicity; Appendices; Index.