Pharmaceutical Bioassays
Methods and Applications
Will be published approx. on 24. November 2009
Book
Hardback
498 pages
978-0-470-22760-2 (ISBN)
Description
The definitive compendium of bioassay procedures and applications
A virtual encyclopedia of key bioassay protocols, this up-to-date, essential resource reviews the methods and applications of bioassays that quantify drug activity and evaluate the validity of pharmacological models.
Demonstrating the specific ways in which various pharmaceutical bioassays interpret the activity of drug molecules, the book covers the evaluation and screening of drug compounds in a wide spectrum of therapeutic categories.
Throughout, the authors use various models to link experimental observations with findings that clarify the effect of drug compounds on cellular biology and measure the pharmacological activity of chemical substances. This provides an important technological platform for successful drug research and clinical therapy, making Pharmaceutical Bioassays an ideal sourcebook for pharmacologists, pharmaceutical and medical researchers, analytical chemists, toxicologists, and students.
Just as a fundamental knowledge of pharmaceutical bioassays is vital to understanding how bioactive agents and new drugs are defined, discovered, and developed, so too is this indispensable reference, which:
* Offers a complete reference on pharmaceutical bioassays and their specific applications in the assessment of therapies for cancer, Alzheimer's, diabetes, epilepsy, inflammation, antimalarials, pharmacogenomics, and other major therapeutic areas
* Covers bioassays that measure toxicity, including those for chemical toxicity and hepatoxicity--a particularly significant consideration in the development of safe and tolerable medications
* Highlights clinically relevant methods, ideas, and techniques to support any pharmaceutical researcher
* Suggests guidelines and systems to enhance communication between pharmacologists, chemists, and biologists
* Provides an informative analysis of pharmaceutical bioassay technologies and lab applications
Reviews / Votes
"In summary, "Pharmaceutical Bioassays" is a useful reference book for research scientists in drug discovery and medicinal chemistry, providing a comprehensive overview of currently available bioassays." (ChemMedChem, 2010)More details
Product info
gebunden
Edition
1. Auflage
Language
English
Place of publication
New York
United States
Target group
Professional and scholarly
Product notice
sewn/stitched
Paper over boards
Dimensions
Height: 240 mm
Width: 161 mm
Thickness: 32 mm
Weight
944 gr
ISBN-13
978-0-470-22760-2 (9780470227602)
Schweitzer Classification
Other editions
Additional editions
E-Book
12/2009
Wiley
€145.99
Available for download
Persons
Shiqi Peng is a Professor and Dean at the School of Chemical Biology and Pharmaceutical Sciences of Capital Medical University in Beijing. He is the author of over 220 journal articles, seven books in China, and over 110 Chinese patents.
Ming Zhao is a Professor and Vice Dean at the School of Chemical Biology and Pharmaceutical Sciences of Capital Medical University in Beijing. She is the author of over 120 journal articles, seven books in China, and over 110 Chinese patents.
Content
Preface.
Contributors.
1. Methods and Application of Anticancer Bioassays (Shiqi Peng).
References and Notes.
2. Methods and Application Antiviral Assay (Chunying Cui, Shiqi Peng and Ming Zhao).
References and Notes.
3. Methods and Application of Antitubercular Assay (Chunying Cui, Shiqi Peng and Ming Zhao).
Reference and Notes.
4. Methods and Application of Thrombus Related Assays (Ming Zhao).
References and Notes.
5. Methods and Application of Anticoagulation Assays (Ming Zhao).
References and Notes.
6. Methods and Application of Blood Pressure Related Assay (Ming Zhao).
References and Notes.
7. Methods and Application of Assays Related to Parkinson's Disease and Graves' Disease (Shiqi Peng).
References and Notes.
8. Methods and Application of Alzheimer's Disease Assay (Shiqi Peng).
References and Notes.
9. Methods and Application of Antiosteoporosis Assay (Ming Zhao).
References and Notes.
10. Methods and Application of Immunomodulating Assay (Shiqi Peng).
References and Notes.
11. Methods and Application of Anti-inflammatory Assays (Ming Zhao).
References and Notes.
12. Methods and Application of Antioxidant Activity Assay (Shiqi Peng).
References and Notes.
13. Methods and Application of Analgesic Assays (Ming Zhao).
References and Notes.
14. Methods and Application of Epilepsy Assays (Ming Zhao, Shiqi Peng and Guohui Cui, ).
References and Notes.
15. Methods and Application of Diabetes Assay (Ming Zhao, Shiqi Peng and Guohui Cui).
References.
16. Methods and Application of Assay for Toxins from Microorganism (Shiqi Peng).
References and Notes.
17. Methods and Application of Toxicity Assay for Chemicals (Shiqi Peng).
References and Notes.
18 Methods and Application of Hepatoxicity and Hepatoprotective Assay (Shiqi Peng).
References and Notes.
19 Methods and Applications of Estrogen Assays (Shiqi Peng).
References and Notes.
20 Methods and Applications of Antimalarial Assays (Shiqi Peng).
References.
21 Methods and Applications of Cytogenetic Receptor and Enzyme Assays (Shiqi Peng).
References and Notes.