Oxford Textbook of Rheumatology

SECTION 1: CLINICAL PRESENTATION OF RHEUMATIC DISEASE; 1.1 Clinical presentation in different age groups; 1.1.1 Assessment and management of the adult patient; 1.1.2 Approach to children and adolescents with arthritis and other rheumatic diseases; 1.1.3 The geriatric age group; 1.1.4 Principles of examination of the musculoskeletal system; 1.1.5 Outcome assessment in rheumatology; 1.1.6 Psychological aspects of rheumatic disease; 1.1.7 Growth and skeletal maturation; 1.2 Common clinical problem; 1.2.1 Spinal problems; 1.2.1.1 Spine - adults; 1.2.1.2 Spinal problems in children; 1.2.2 Regional problems; 1.2.2.1 Regional disorders of the upper limbs in adults; 1.2.2.2 Regional problems of the lower extremeties; 1.2.3.4 Regional problems of the arm and leg in children; 1.2.3 Extra-articular presentation of rheumatic diseases; 1.3 Views from different perspectives; 1.3.1 Pregnancy; 1.3.1.2 Antirheumatic drugs in pregnancy and lactation; 1.3.2 The skin and rheumatic disease; 1.3.3 Neurological complications of rheumatic diseases; 1.3.4 Cardiovascular complications of rheumatic diseases; 1.3.5 Respiratory; 1.3.6 Gastroenterology; 1.3.7 Endocrinology in the rheumatic diseases; 1.3.8 Haematology and oncology in rheumatology; 1.3.9 An anesthetic perspective of rheumatic disease; 1.3.10 An ophthalmological perspective of rheumatological disease; 1.3.11 Nephrology; 1.3.12 Psychiatric issues in rheumatology; SECTION 2: PATHOPHYSIOLOGY OF MUSCULOSKELETAL DISEASE; 2.1 Molecular genetics and its relevance in rheumatology; 2.2 Molecular abnormalities of collagen and connective tissue; 2.3 Articular cartilage; 2.4 Bone in health and disease; 2.5 The physiology of the joint and its disturbance in inflammation; 2.6 Skeletal muscle damage; 2.7 Biomechanics of articulation and derangements in disease; 2.8 The neurophysiology of pain; SECTION 3: THE PROCESS OF INFLAMMATION; 3.1 Cells and mediators; 3.2 Lymphocyte traffic in inflammation; 3.3 Specific immune responses; 3.4 Animal models of arthritis; 3.5 Modification of inflammation; 3.5.1 Non-steroidal anti-inflammatory drugs; 3.5.2 Antirheumatic drugs; 3.5.3 Therapeutic immunomodulation; SECTION 4: INVESTIGATION OF THE RHEUMATIC DISEASES; 4.1 Acute phase response; 4.2 Haematology; 4.3 Biochemistry; 4.4 Microbiology and diagnostic serology; 4.5 Autoantibody profile; 4.6 Joint fluid; 4.7 Gene marker analysis; 4.8 Immune complex detection; 4.9 Imaging; 4.9.1 Imaging of adult musculoskeletal disease; 4.9.2 Imaging of childhood joint disease; 4.10 Histopathological diagnosis; 4.11 Electrophysiology; SECTION 5: THE SCOPE OF RHEUMATIC DISEASES; 5.1 Epidemiology; 5.1.1 Epidemiology and the rheumatic diseases; 5.1.2 Epidemiology of rheumatic diseases in selected non-European populations; 5.2 Nosology of the chronic inflammatory rheumatic diseases; 5.3 Infections; 5.3.1 Pyogenic arthritis in adults; 5.3.2 Pyogenic arthritis in children; 5.3.3 Osteomyelitis and associated conditions; 5.3.4 Lyme disease; 5.3.5 Viral arthritis; 5.3.6 Rheumatological aspects of HIV infection; 5.3.7 Mycobacterial; 5.3.8 Brucellar arthritis; 5.3.9 Parasites; 5.3.10 Fungal arthritis; 5.3.11 Immunodeficiency; 5.3.12 Rheumatic fever: aetiology, diagnosis, and treatment; 5.4 Rheumatoid arthritis; 5.4.1 Immunopathogenesis of rheumatoid arthritis; 5.4.2 Rheumatoid arthritis - the clinical picture; 5.4.3 Juvenile rheumatoid arthritis (rheumatoid factor positive polyarthritis); 5.5 Spondylarthropathies; 5.5.1 Spondylarthropathy, undifferentiated spondylarthritis, and overlap; 5.5.2 Spondyarthropathy in children; 5.5.3 Ankylosing spondylitis; 5.5.4 Psoriatic arthritis; 5.5.5 Reactive arthropathy, Reiter's syndrome, and enteric arthropathy in adults; 5.6 Arthropathies primarily occurring in childhood; 5.6.1 Pauciarticular-onset juvenile chronic arthritis; 5.6.2 Systemic-onset juvenile chronic arthritis; 5.6.3 Rheumatoid factor (RF) negative polyarthritis in children ('seronegative polyarthritis'); 5.7 Systemic lupus erythematosus; 5.7.1 Systemic lupus erythematosus in adults; 5.7.2 Paediatric systemic lupus erythematosus; 5.7.3 The antiphospholipid antibody syndrome; 5.8 Scleroderma and related disorders; 5.9.1 Polymyositis and dermatomyositis in adults; 5.9.2 Polymyositis and dermatomyositis: paediatric aspects; 5.10 Sjogren's syndrome; 5.11 Primary vasculitides; 5.11.1 Classification of vasculitis; 5.11.2 Wegener's granulomatosis; 5.11.3 Classical polyarteritis nodosa, microscopic polyarteritis, and Churg-Strauss syndrome; 5.11.4 Small vessel vasculitis; 5.11.5 Polymyalgia rheumatica; 5.11.6 Large vessel vasculitis; 5.11.7 Behcet's syndrome; 5.11.8 Primary vasculitis in children; 5.12 Overlap syndromes in adults and children; 5.13 Miscellaneous inflammatory conditions; 5.13.1 Amyloidosis; 5.13.2 Familial Mediterranean fever; 5.13.3 Panniculitis; 5.13.4 Neutrophilic dermatoses; 5.13.5 Sarcoidosis; 5.13.6 The chronic, infantile, neurological, cutaneous and articular syndrome (CINCA); 5.13.7 Multicentric reticulohistiocytosis; 5.13.8 Hyperlipidaemias; 5.13.9 Coagulation arthropathies; 5.14 Soft-tissue rheumatism; 5.15 Osteoarthritis; 5.16 Crystal arthropathies; 5.17 Diseases of the bone and cartilage; 5.17.1 Osteoporosis and osteomalacia; 5.17.2 Paget's disease of the bone; 5.17.3 Miscellaneous diseases of bone, cartilage, and synovium; 5.17.4 Diseases of bone and cartilage: paediatric aspects; 5.18 Disorders of the spine; 5.18.1 Intervertebral disc disease and other mechanical disorders of the back; 5.18.2 Cervical pain syndromes; 5.19.1 Neoplasia; 5.19.2 Algodystrophy (reflex sympathetic dystrophy syndrome); 5.19.3 Rheumatic complications of drugs and toxins; SECTION 6: INTERVENTION, REHABILITATION, AND SPORTS MEDICINE; 6.1 The surgery of rheumatic disease in adults; 6.2 The role of surgery in the management of rheumatic diseases in children; 6.3 Rehabilitation in inflammatory joint disease; 6.4 Non-surgical rehabiliation of children with rheumatic diseases; 6.5 Corticosteroid injection therapy; 6.6 Sports medicine; 6.7 Sports injuries