Designs for Clinical Trials
Perspectives on Current Issues
Published on 29. November 2013
Book
Paperback/Softback
XIV, 206 pages
978-1-4614-2953-1 (ISBN)
Description
This book will examine current issues and controversies in the design of clinical trials, including topics in adaptive and sequential designs, the design of correlative genomic studies, the design of studies in which missing data is anticipated. Each chapter will be written by an expert conducting research in the topic of that chapter. As a collection, the chapters would be intended to serve as a guidance for statisticians designing trials.
Reviews / Votes
From the reviews:
"'Designs for Clinical Trials: Perspectives on Current Issues' fills the gap between professional journals and school textbooks by addressing a few important, rapidly evolving statistical topics. The book is intended for statistical practitioners like clinical trialists who actively use statistics but do not follow the literature on recent biostatistical thinking." (Norman M. Goldfarb, Journal of Clinical Research Best Practices, Vol. 9 (2), February, 2013)More details
Series
Edition
2012 ed.
Language
English
Place of publication
New York
United States
Target group
Professional and scholarly
Research
Illustrations
XIV, 206 p.
Dimensions
Height: 235 mm
Width: 155 mm
Thickness: 13 mm
Weight
341 gr
ISBN-13
978-1-4614-2953-1 (9781461429531)
DOI
10.1007/978-1-4614-0140-7
Schweitzer Classification
Other editions
Additional editions
E-Book
10/2011
1st Edition
Springer
€149.79
Available for download
Book
10/2011
Springer
€160.49
Shipment within 15-20 days
Content
New designs for phase I dose finding studies.- Phase II/III designs for trials.- Design issues for clinical studies with genomic measurements.- Designing studies with longitudinal measurements subject to dropout.- Issues in sample size re-estimation.- Adaptive designs.- The design of non-inferiority trials.- Issues in the design of HIV prevention trials.- Randomization algorithms.- Sequential designs for phase III studies.- Case studies of difficult designs.- Ethical issues in the design of trials.- Index.