Designs for Clinical Trials
Perspectives on Current Issues
Published on 8. October 2011
Book
Hardback
XIV, 206 pages
978-1-4614-0139-1 (ISBN)
Description
This book will examine current issues and controversies in the design of clinical trials, including topics in adaptive and sequential designs, the design of correlative genomic studies, the design of studies in which missing data is anticipated. Each chapter will be written by an expert conducting research in the topic of that chapter. As a collection, the chapters would be intended to serve as a guidance for statisticians designing trials.
Reviews / Votes
From the reviews:
"'Designs for Clinical Trials: Perspectives on Current Issues' fills the gap between professional journals and school textbooks by addressing a few important, rapidly evolving statistical topics. The book is intended for statistical practitioners like clinical trialists who actively use statistics but do not follow the literature on recent biostatistical thinking." (Norman M. Goldfarb, Journal of Clinical Research Best Practices, Vol. 9 (2), February, 2013)More details
Series
Edition
2012
Language
English
Place of publication
New York
United States
Target group
Professional and scholarly
Research
Illustrations
21 s/w Abbildungen, 7 farbige Abbildungen
XIV, 206 p.
Dimensions
Height: 241 mm
Width: 160 mm
Thickness: 17 mm
Weight
500 gr
ISBN-13
978-1-4614-0139-1 (9781461401391)
DOI
10.1007/978-1-4614-0140-7
Schweitzer Classification
Other editions
Additional editions
Book
11/2013
Springer
€160.49
Shipment within 15-20 days
E-Book
10/2011
1st Edition
Springer
€149.79
Available for download
Content
New designs for phase I dose finding studies.- Phase II/III designs for trials.- Design issues for clinical studies with genomic measurements.- Designing studies with longitudinal measurements subject to dropout.- Issues in sample size re-estimation.- Adaptive designs.- The design of non-inferiority trials.- Issues in the design of HIV prevention trials.- Randomization algorithms.- Sequential designs for phase III studies.- Case studies of difficult designs.- Ethical issues in the design of trials.- Index.