Prostate Cancer
Biology, Genetics, and the New Therapeutics
Published on 1. January 2001
Book
Hardback
XVIII, 531 pages
978-0-89603-868-4 (ISBN)
Description
This book embraces the wide field of prostate cancer genetics, biology, and therapy. It seems most appropriate to dedicate it to Donald S. Coffey, PhD, whose research vision is an inspiration to his colleagues and friends. Unraveling the secrets of prostate cancer is an intricate and sometimes frustrating process involving many researchers and many institutions. No one has seen through to the end of this road, and the list of researchers who have contributed to our understanding of the disease processes of prostate cancer is already a long one. But Donald Coffey stands out in his personal qualities as surely as in his roles as teacher and researcher. In the dedicatory article that begins this volume, Dr. Ward has spoken for all of us about Don Coffey's unique determination to build the road to defeat prostate cancer. This book is divided into three sections: Cancer Genetics, Cancer Biology, and Cancer Therapeutics. These sections, like the skill and knowledge of the contributors, overlap in many dimensions. The divisions between sections are somewhat arbitrary and have been made expressly for the convenience of the reader. The reader will find chapters in each section that illuminate aspects ofthe genetics, biology, and therapy of prostate cancer. Nothing better illustrates the breadth of the research being conducted today by these distinguished groups, who truly understand and appreciate the power of multi disciplinary and translational approaches to deciphering the intricacy of the object of this research.
Reviews / Votes
the editors have done a remarkable job in selecting the topics and compiling the various articles into a comprehensive and easily accessible volume. The chapters are concise and informative, covering highly innovative studies being conducted in the field of recent years the complexity of prostate cancer biology is well represented in the book, and the resourceful information can benefit not only those who are interested in prostate biology, but also those researchers employing molecular and cellular approaches to solve other important biological questions. - Quarterly Review of Biology a welcome addition to the literature The main strength of this book is that experts from several disciplines have contributed their thoughts on recent advances in prostate cancer I strongly recommend this book to researchers who study prostate cancer, whether at the bench or at the bedside, and to clinicians who treat patients with prostate the book covers our current knowledge of prostate cancer and its treatment and helps define the foundation for future directions. - New England Journal of Medicine Well researched and extensively referenced, the book provides a valuable source of information on the current state of understanding of the molecular biology of prostate cancer, and the treatment modalities in routine clinical practice. - ACP News Each chapter is presented in a way that provides all available knowledge on the subject and the book structure allows readers to use a single section or chapter according to their interests. All these characteristics make the book a valuable tool to general oncologists or urologists interested in updating their basic knowledge of prostate cancer. Annals of OncologyMore details
Series
Language
English
Place of publication
NJ
United States
Target group
College/higher education
Professional and scholarly
Illustrations
58
1 farbige Abbildung, 58 s/w Abbildungen
Dimensions
Height: 25.4 cm
Width: 17.8 cm
Weight
1343 gr
ISBN-13
978-0-89603-868-4 (9780896038684)
DOI
10.1007/978-1-59259-009-4
Schweitzer Classification
Other editions
New editions
Leland W. K. Chung | William B. Isaacs | Jonathan W. Simons
Prostate Cancer
Biology, Genetics, and the New Therapeutics
Book
07/2007
2nd Edition
Humana Press Inc.
€160.49
Shipment within 15-20 days
Additional editions
E-Book
12/2000
1st Edition
Humana
€85.59
Available for download
Content
Part I. Introduction. Building the Road to Defeat Prostate Cancer: A Dedication to Donald S. Coffey, W. Steven Ward. Part II. Cancer Genetics. Hereditary Prostate Cancer, William B. Isaacs, Jianfeng Xu, and Patrick C. Walsh. AR Gene Alterations in Prostate Cancer Progression, Tapio Visakorpi. Lethal Metastatic Human Prostate Cancer: Autopsy Studies and Characteristics of Metastases, G. Steven Bova, Kirk M. Chan-Tack, and William W. LeCates. Tumor Suppressor Genes in Prostate Cancer, Robert Bookstein. Androgen Receptor Polymorphisms and Prostate Cancer Risk, Phillip G. Febbo and Philip W. Kantoff. The Genetic Epidemiology of Prostate Cancer: Closing in on a Complex Disease, Ronald K. Ross, Juergen K. V. Reichardt, Sue Ann Ingles, and Gerhard A. Coetzee. Determination of Gene and Chromosome Dosage in Prostatic Intraepithelial Neoplasia and Prostatic Carcinoma by Molecular Cytogenetic Techniques, Junqi Qian and Robert B. Jenkins. Genetic Alterations in Prostatic Intraepithelial Neoplasia (PIN), Paul H. Duray, David K. Ornstein, Cathy D. Vocke, Stephen M. Hewitt, Kristina A. Cole, John W. Gillespie, Chad R. Englert, Emanuel F. Petricoin, David B. Krizman, W. Marston Linehan, and Michael R. Emmert-Buck. Xenograft Models and the Molecular Biology of Human Prostate Cancer, Robert E. Reiter and Charles L. Sawyers. Comprehensive Analyses of Prostate Gene Expression, Peter S. Nelson. Part III. Cancer Biology. The Role of Nuclear Matrix and Cytoskeleton in Cancer, Robert H. Getzenberg. The Role of Cell Adhesion Molecules in Prostate Development and Carcinogenesis, Jer-Tsong Hsieh. Ligand Dependent and Independent Activation of Androgen Receptor, Gloria R. Mora and Donald J. Tindall. Tyrosine Kinases and Cellular Signaling in Prostate Cancer, Hsing-Jien Kung, Clifford G. Tepper, and Ralph W. deVere White. Molecular Pathways that Underlie Prostate Cancer Progression: The Role of Caveolin-1, Timothy C. Thompson, Terry L. Timme, Likun Li, Chengzen Ren, Alexi Goltsov, Salahaldin Tahir, and Guang Yang. Angiogenesis and Prostate Cancer, Ingrid B. J. K. Joseph and John T. Isaacs. Prostate Specific Membrane Antigen, Denise S. O'Keefe, Dean J. Bacich, and Warren W. D. Heston. Targeting Antiapoptotic Genes Upregulated by Androgen Withdrawal Using Antisense Oligodeoxynucleotides to Enhance Androgen- and Chemo-Sensitivity in Prostate Cancer, Martin E. Gleave, Hideaki Miyake, Colleen Nelson, Paul Rennie, and Simon Leung. Stromal-Epithelial Interaction: From Bench to Bedside, Leland W. K. Chung and Haiyen E. Zhau. Part IV. Cancer Therapeutics. Chemoprevention of Prostate Cancer, James D. Brooks and William G. Nelson. Anatomic Radical Retropubic Prostatectomy for Prostate Cancer, Misop Han and Alan W. Partin. Radiation Therapy as Applied to Prostate Cancer: Clinical, Technical, and Biologic Considerations, Naren R. Ramakrishna and Theodore L. DeWeese. Prostate Cancer Chemotherapy: Closing Out a Century and Opening a New One, Jeffrey M. Kamradt and Kenneth J. Pienta. The Role of Small Bioactive Peptides and Cell Surface Peptidases in Androgen Independent Prostate Cancer, Joel B. Nelson. Development of Dendritic Cell-Based Prostate Cancer Vaccine, Benjamin A. Tjoa and Gerald P. Murphy. Antiprogression Agents for Prostate Cancer, Hadley M. Wood and Michael A. Carducci. Human Gene Therapy for Urological Oncology, Fernando Ferrer, Jonathan W. Simons, and Ronald Rodriguez. Chemoprevention Trials for Prostate Cancer, Peter Greenwald and Ronald Lieberman. Index.